K. Mechtler

Publication List Details

Period

2005 - 2008

Number

15

Co-Authors

Spatial organization of a ubiquitous eukaryotic kinetochore protein network in Drosophila chromosomes. (2007)

Schittenhelm, R B, Heeger, S, Althoff, F, Walter, A, Heidmann, S, Mechtler, K, ...

Chromosome segregation during meiosis and mitosis depends on the assembly of functional kinetochores within centromeric regions. Centromeric DNA and kinetochore proteins show surprisingly little...

Transloading of tumor cells with foreign major histocompatibility complex class I peptide ligand: a novel general strategy for the generation of potent cancer vaccines.

Schmidt, W, Steinlein, P, Buschle, M, Schweighoffer, T, Herbst, E, Mechtler, K, ...

The major hurdle to be cleared in active immunotherapy of cancer is the poor immunogenicity of cancer cells. In previous attempts to overcome this problem, whole tumor cells have been used as...

Coupling of adenovirus to transferrin-polylysine/DNA complexes greatly enhances receptor-mediated gene delivery and expression of transfected genes.

Wagner, E, Zatloukal, K, Cotten, M, Kirlappos, H, Mechtler, K, Curiel, D T, ...

We are developing efficient methods for gene transfer into tissue culture cells. We have previously shown that coupling of a chimeric adenovirus with polylysine allowed the construction of an...

Transferrin-polycation-mediated introduction of DNA into human leukemic cells: stimulation by agents that affect the survival of transfected DNA or modulate transferrin receptor levels.

Cotten, M, Längle-Rouault, F, Kirlappos, H, Wagner, E, Mechtler, K, Zenke, M, ...

We have subverted a receptor-mediated endocytosis event to transport genes into human leukemic cells. By coupling the natural iron-delivery protein transferrin to the DNA-binding polycations...

Transloading of tumor cells with foreign major histocompatibility complex class I peptide ligand: a novel general strategy for the generation of potent cancer vaccines.

Schmidt, W, Steinlein, P, Buschle, M, Schweighoffer, T, Herbst, E, Mechtler, K, ...

The major hurdle to be cleared in active immunotherapy of cancer is the poor immunogenicity of cancer cells. In previous attempts to overcome this problem, whole tumor cells have been used as...

Coupling of adenovirus to transferrin-polylysine/DNA complexes greatly enhances receptor-mediated gene delivery and expression of transfected genes.

Wagner, E, Zatloukal, K, Cotten, M, Kirlappos, H, Mechtler, K, Curiel, D T, ...

We are developing efficient methods for gene transfer into tissue culture cells. We have previously shown that coupling of a chimeric adenovirus with polylysine allowed the construction of an...

Transferrin-polycation-mediated introduction of DNA into human leukemic cells: stimulation by agents that affect the survival of transfected DNA or modulate transferrin receptor levels.

Cotten, M, Längle-Rouault, F, Kirlappos, H, Wagner, E, Mechtler, K, Zenke, M, ...

We have subverted a receptor-mediated endocytosis event to transport genes into human leukemic cells. By coupling the natural iron-delivery protein transferrin to the DNA-binding polycations...