Yousry, T.A., Habil, M., Major, E.O., Ryschkewitsch, C., Fahle, G., Fischer, S., ...
Background: Progressive multifocal leukoencephalopathy (PML) was reported to have developed in three patients treated with natalizumab. We conducted an evaluation to determine whether PML had...
Radiological and clinicopathological features of orbital xanthogranuloma
Miszkiel, K, Sohaib, S, Rose, G, Cree, I, Moseley, I
BACKGROUND—Orbital xanthogranuloma, a diagnosis confirmed histologically, occurs rarely in adults and children. With its characteristic macroscopic appearance the adult form may be associated with...
Brex, P, Miszkiel, K, O'Riordan, J, Plant, G, Moseley, I, Thompson, A, ...
OBJECTIVES—With increasing evidence that permanent tissue damage occurs early in the course of multiple sclerosis, it is important that treatment trials include patients in the earliest stages of...
Measurement of spinal cord area in clinically isolated syndromes suggestive of multiple sclerosis
Brex, P, Leary, S, O'Riordan, J, Miszkiel, K, Plant, G, Thompson, A, ...
Atrophy of the spinal cord is known to occur in multiple sclerosis but the cause and the timing of its onset are not clear. Recent evidence suggests that atrophy may start to occur early in the...
Dalton, C, Brex, P, Jenkins, R, Fox, N, Miszkiel, K, Crum, W, ...
Background: In patients with clinically isolated syndromes (CIS) suggestive of multiple sclerosis (MS), the extent of brain magnetic resonance imaging (MRI) lesion load influences the probability and...
Spinal cord MRI in clinically isolated optic neuritis
Dalton, C, Brex, P, Miszkiel, K, Fernando, K, MacManus, D, Plant, G, ...
Results: Eighty one (70%) patients had brain lesions and 31 (27%) had cord lesions. Cord lesions were seen in 12% with a normal brain MRI, 21% with between one and eight brain lesions, and 45% with...
Wilkinson, I., Lunn, S., Miszkiel, K., Miller, R., Paley, M., Williams, I., ...
OBJECTIVE—To investigate MRI and proton spectroscopy changes in five patients with HIV associated dementia complex (HADC) treated with antiretroviral therapy. METHODS—Three markers were...