K. Miura

Publication List Details

Period

1979 - 2009

Number

236

Co-Authors

MgO barrier-perpendicular magnetic tunnel junctions with CoFe/Pd multilayers and ferromagnetic insertion layers (2009)

Mizunuma, K., Ikeda, S., Park, J. H., Yamamoto, H., Gan, H., Miura, K., ...

The authors studied an effect of ferromagnetic (Co20Fe60B20 or Fe) layer insertion on tunnel magnetoresistance (TMR) properties of MgO-barrier magnetic tunnel junctions (MTJs) with CoFe/Pd multilayer...

Brown-Rho Scaling in the Strong Coupling Lattice QCD (2008)

Ohnishi, A., Kawamoto, N., Miura, K.

We examine the Brown-Rho scaling for meson masses in the strong coupling limit of lattice QCD with one species of staggered fermion. Analytical expression of meson masses is derived at finite...

Correlates of Capture of Attention and Inhibition of Return across Stages of Visual Processing (2008)

Michael C. Dorris, Tracy L. Taylor, Raymond M. Klein, Douglas P. Munoz, J Neurophysiol, H. Tabata, ...

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Canceling Planned Action: An fMRI Study of Countermanding Saccades (2008)

Krista Kornylo, Natalie Dill, Melissa Saenz, Richard J. Krauzlis, J Neurophysiol, H. Tabata, ...

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[Abstract]   [Full Text]   [PDF] Learning-Induced Enduring Changes in Functional Connectivity among Prefrontal Cortical Neurons (2008)

Stuart N. Baker, Roger N. Lemon, J Neurophysiol, K. Miura, Y. Tsubo, M. Okada, ...

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Phase diagram at finite temperature and quark density in the strong coupling region of lattice QCD for colour SU(3) (2007)

Ohnishi, A ., Kawamoto, N., Miura, K.

We study the phase diagram of quark matter at finite temperature (T) and chemical potential (μ) in the strong coupling region of lattice QCD for colour SU(3). Baryon has effects to extend the hadron...

Phase diagram at finite temperature and quark density in the strong coupling region of lattice QCD for colour SU(3) (2007)

Ohnishi, A ., Kawamoto, N., Miura, K.

We study the phase diagram of quark matter at finite temperature (T) and chemical potential (μ) in the strong coupling region of lattice QCD for colour SU(3). Baryon has effects to extend the hadron...

Strong coupling limit/region of lattice QCD (2007)

Ohnishi, A., Kawamoto, N., Miura, K., Tsubakihara, K., Maekawa, H.

We study the phase diagram of quark matter and nuclear properties based on the strong coupling expansion of lattice QCD. Both of baryon and finite coupling correction are found to have effects to...

"Quill" writing with ultrashort light pulses in transparent materials (2007)

Kazansky, P.G., Yang, W., Bricchi, E., Bovatsek, J., Arai, A., Shimotsuma, Y., ...

A remarkable phenomenon in ultrafast laser processing of transparent materials, in particular, silica glass, manifested as a change in material modification by reversing the writing direction is...

Phase diagram at finite temperature and quark density in the strong coupling region of lattice QCD for color SU(3) (2007)

Ohnishi, A., Kawamoto, N., Miura, K.

We study the phase diagram of quark matter at finite temperature (T) and chemical potential (mu) in the strong coupling region of lattice QCD for color SU(3). Baryon has effects to extend the hadron...

Phase diagram at finite temperature and quark density in the strong coupling limit of lattice QCD for color SU(3) (2007)

Kawamoto, N., Miura, K., Ohnishi, A., Ohnuma, T.

We study the phase diagram of quark matter at finite temperature (T) and chemical potential (µ) in the strong coupling limit of lattice QCD for color SU(3). We derive an analytical expression of the...

Phase diagram at finite temperature and quark density in the strong coupling limit of lattice QCD for color SU(3) (2007)

Kawamoto, N., Miura, K., Ohnishi, A., Ohnuma, T.

We study the phase diagram of quark matter at finite temperature (T) and chemical potential (µ) in the strong coupling limit of lattice QCD for color SU(3). We derive an analytical expression of the...

Powder diffraction studies on proteins: An overview of data collection approaches (2007)

Margiolaki, I., Wright, J. P., Fitch, A. N., Fox, G. C., Labrador, A., Von Dreele, R. B., ...

Following the seminal work of Von Dreele, high quality powder X-ray diffraction studies on proteins are being established as a valuable complementary technique to single-crystal measurements. Several...

Quill writing with ultrashort light pulses in transparent optical materials (2007)

Kazansky, P.G., Yang, W., Bricchi, E., Bovatsek, J., Arai, A., Shimotsuma, Y., ...

Writing in silica glass in opposite directions can be different. The phenomenon resembles quill writing and is interpreted in terms of anisotropic trapping of electron plasma by a tilted front of the...

Joint LIGO and TAMA300 search for gravitational waves from inspiralling neutron star binaries (2006)

Abbott, B., Abbott, R., Adhikari, R., Ageev, A., Agresti, J., Ajith, P., ...

We search for coincident gravitational wave signals from inspiralling neutron star binaries using LIGO and TAMA300 data taken during early 2003. Using a simple trigger exchange method, we perform an...

Joint LIGO and TAMA300 search for gravitational waves from inspiralling neutron star binaries (2006)

Abbott, B., Abbott, R., Adhikari, R., Ageev, A., Agresti, Juri, Ajith, P., ...

We search for coincident gravitational wave signals from inspiralling neutron star binaries using LIGO and TAMA300 data taken during early 2003. Using a simple trigger exchange method, we perform an...

Results of the search for inspiraling compact star binaries from TAMA300's observation in 2000-2004 (2006)

Akutsu, Tomomi, Akutsu, Tomotadu, Ando, Masaki, Arai, Koji, Araya, Akito, Asada, H., ...

We analyze the data of the TAMA300 detector to search for gravitational waves from inspiraling compact star binaries with masses of the component stars in the range 1M[sun]–3M[sun]. In this...

Comparison of the incidence of sibling cannibalism between male-killing Spiroplasma infected and uninfected clutches of a predatory ladybird beetle, Harmonia axyridis (Coleoptera: Coccinellidae) (2006)

Nakamura, K., Miura, K., Ueno, H.

The incidence of sibling cannibalism in clutches of Harmonia axyridis infected by the male-killing Spiroplasma was compared with that in uninfected clutches, and the way in which fitness compensation...

Network-based de-noising improves prediction from microarray data (2006)

Kato, T., Murata, Y., Miura, K., Asai, K., Horton, P.B., Tsuda, K., ...

Prediction of human cell response to anti-cancer drugs (compounds) from microarray data is a challenging problem, due to the noise properties of microarrays as well as the high variance of living...

Phase diagram at finite temperature and quark density in the strong coupling limit of lattice QCD for color SU(3) (2005)

Kawamoto, N., Miura, K., Ohnishi, A., Ohnuma, T.

We study the phase diagram of quark matter at finite temperature (T) and finite chemical potential (mu) in the strong coupling limit of lattice QCD for color SU(3). We derive an analytical expression...

Search for optimal measure for discriminating spike trains with different randomness (2005)

Miura, K., Okada, M., Shinomoto, S.

We wish to discriminate spike sequences based on the degree of irregularity. For this purpose, we search for a rational expressions of quadratic functions of consecutive interspike intervals that...

Regional and laminar differences in in vivo firing patterns of primate cortical neurons (2005)

Y. Tsubo, T. Fukai, H. Shimazaki, S. Shinomoto, D. Durstewitz, T. Gabriel, ...

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Effect of re-expansion after short-period lung collapse on pulmonary capillary permeability and pro-inflammatory cytokine gene expression in isolated rabbit lungs (2004)

Funakoshi, T., Ishibe, Y., Okazaki, N., Miura, K., Liu, R., Nagai, S., ...

Background. Re‐expansion pulmonary oedema is a rare complication caused by rapid re‐expansion of a chronically collapsed lung. Several cases of pulmonary oedema associated with...

Effect of re-expansion after short-period lung collapse on pulmonary capillary permeability and pro-inflammatory cytokine gene expression in isolated rabbit lungs (2004)

Funakoshi, T., Ishibe, Y., Okazaki, N., Miura, K., Liu, R., Nagai, S., ...

Background. Re-expansion pulmonary oedema is a rare complication caused by rapid re-expansion of a chronically collapsed lung. Several cases of pulmonary oedema associated with one-lung ventilation...

Effect of re-expansion after short-period lung collapse on pulmonary capillary permeability and pro-inflammatory cytokine gene expression in isolated rabbit lungs (2004)

Funakoshi, T., Ishibe, Y., Okazaki, N., Miura, K., Liu, R., Nagai, S., ...

Background. Re-expansion pulmonary oedema is a rare complication caused by rapid re-expansion of a chronically collapsed lung. Several cases of pulmonary oedema associated with one-lung ventilation...

Study of blind thrust faults underlying Tokyo and Osaka urban areas using a combination of high-resolution seismic reflection profiling and continuous coring (2003)

Sugiyama, Y., Mizuno, K., Nanayama, F., Sugai, T., Yokota, H., Hosoya, T., ...

We acquired high-resolution seismic reflection profiles and continuously cored boreholes to evaluate active flexures produced by major blind thrust fault systems within two densely populated...

How does infection with parthenogenesis-inducing Wolbachia reduce the fitness of Trichogramma? (2001)

Tagami, Y., Miura, K., Stouthamer, R.

We analyzed the survival rate of the immature stages of Trichogramma species and lines that differed in their mode of reproduction. Specifically, we compared the mortality of arrhenotokous (W-),...

Memorized polarization-dependent light scattering in rare-earth-ion-doped glass (2000)

Qui, J., Kazansky, P.G., Si, J., Miura, K., Mitsuyu, T., Hirao, K., ...

We report the observation of memorized polarization-dependent light scattering in a Eu2 + -doped fluoroaluminate glass sample. Anisotropic light scattering along the plane of the light polarization...

The relationship between waist-to-hip ratio and occupational status and life-style factors among middle-aged male and female Japanese workers (1999)

Ishizaki, M., Yamada, Y., Morikawa, Y., Noborisaka, Y., Ishida, M., Miura, K., ...

As a marker of body fat distribution and therefore level of obesity, the waist-to-hip ratio (W:H) is a good indicator of coronary heart disease risk status. The present study investigated the...

Human Basophils and Mast Cells. (1998)

Lavens-Phillips, Sandra, Miura, K., Schroeder, J. T.

Critical progress has been made in the identification and characterization of cells and mediators involved in allergic inflammation. Accumulating evidence supports the importance of cell adhesion...

Structural analysis of SiO2 gel films by high energy electron diffraction (1994)

Ohsaki, H., Miura, K., Imai, A., Tada, M., Aegerter, Michel A.

The structure of SiO2 gel-films prepared from acid and basic TEOS solutions is analyzed by high energy transmission electron diffraction method. The Si-O bond length of gel-films is 1.58 to 1.60 Å,...

Studies on nucleic acid interactions I. Stabilities of mini-duplexes (dG2A4XA4G2.dC2T4YT4C2) and self-complementary d(GGGAAXYTTCCC) containing deoxyinosine and other mismatched bases (1986)

Kawase, Y., Iwai, S., Inoue, H., Miura, K., Ohtsuka, E.

The thermal stability of DNA duplexes containing deoxyinosine in a pairing position in turn with each of the four major deoxynucleotides has been investigated by measuring ultraviolet-absorbance at...

BRI LLOUIN SCATTERING STUDY OF THE INCOMMENSURATE (ANTIFERROELECTRIC) PHASE TRANSITION IN SODIUM NITRITE (1981)

Yagi, T., Hidaka, Y., Miura, K.

The Brillouin scattering spectra of NaNO2 have been observed as a function of temperature near the two phase transition points ; normal (paraelectric)-incomensurate (antiferroelectric) and...

BRI LLOUIN SCATTERING STUDY OF THE INCOMMENSURATE (ANTIFERROELECTRIC) PHASE TRANSITION IN SODIUM NITRITE (1981)

Yagi, T., Hidaka, Y., Miura, K.

The Brillouin scattering spectra of NaNO2 have been observed as a function of temperature near the two phase transition points ; normal (paraelectric)-incomensurate (antiferroelectric) and...

BRI LLOUIN SCATTERING STUDY OF THE INCOMMENSURATE (ANTIFERROELECTRIC) PHASE TRANSITION IN SODIUM NITRITE (1981)

Yagi, T., Hidaka, Y., Miura, K.

The Brillouin scattering spectra of NaNO2 have been observed as a function of temperature near the two phase transition points ; normal (paraelectric)-incomensurate (antiferroelectric) and...

Crystal structure of an engineered subtilisin inhibitor complexed with bovine trypsin.

Takeuchi, Y, Nonaka, T, Nakamura, K T, Kojima, S, Miura, K, Mitsui, Y

Proteinase specificity of a proteinaceous inhibitor of subtilisin (SSI; Streptomyces subtilisin inhibitor) can be altered so as to strongly inhibit trypsin simply by replacing P1 methionine with...

Functional conversion of the homologous proteins alpha-lactalbumin and lysozyme by exon exchange.

Kumagai, I, Takeda, S, Miura, K

Exons of eukaryotic genes that encode proteins frequently appear to encode structural and/or functional protein units [Gilbert, W. (1978) Nature (London) 271, 501; Blake, C.C.F. (1979) Nature...

Streptomyces serine protease (SAM-P20): recombinant production, characterization, and interaction with endogenous protease inhibitor.

Taguchi, S, Suzuki, M, Kojima, S, Miura, K, Momose, H

Previously, we isolated a candidate for an endogenous target enzyme(s) of the Streptomyces subtilisin inhibitor (SSI), termed SAM-P20, from a non-SSI-producing mutant strain (S. Taguchi, A. Odaka, Y....

Streptomyces subtilisin inhibitor-like proteins are distributed widely in streptomycetes.

Taguchi, S, Kikuchi, H, Suzuki, M, Kojima, S, Terabe, M, Miura, K, ...

Streptomyces subtilisin inhibitor-like proteins were found to be distributed widely in streptomycetes by using the combination of the convenient, newly developed plate assay system and an established...

Phosphatidylinositol 4,5-bisphosphate phosphatase regulates the rearrangement of actin filaments.

Sakisaka, T, Itoh, T, Miura, K, Takenawa, T

Phosphatidylinositol 4,5-bisphosphate (PIP2) reorganizes actin filaments by modulating the functions of a variety of actin-regulatory proteins. Until now, it was thought that bound PIP2 is hydrolyzed...

Lack of correlation between interferon production of mononuclear cells and virus replication in chronic hepatitis B virus infection.

Kinoshita, R, Miura, K, Suzuki, S, Uchino, H

Interferon production in hepatitis B virus carriers with normal liver functions was preserved, whereas in carriers with chronic hepatitis it was depressed. The lower interferon production in...

Synthesis and hybridization studies on two complementary nona(2'-O-methyl)ribonucleotides.

Inoue, H, Hayase, Y, Imura, A, Iwai, S, Miura, K, Ohtsuka, E

2'-O-Methyl derivatives of the common ribonucleosides except for guanosine were synthesized via the 2'-O-methylation of appropriately-protected nucleosides with CH3I in the presence of Ag2O. The...

Unusual anticodon loop structure found in E.coli lysine tRNA.

Watanabe, K, Hayashi, N, Oyama, A, Nishikawa, K, Ueda, T, Miura, K

Although both tRNA(Lys) and tRNA(Glu) of E. coli possess similar anticodon loop sequences, with the same hypermodified nucleoside 5-methylaminomethyl-2-thiouridine (mnm5s2U) at the first position of...

Most compact hairpin-turn structure exerted by a short DNA fragment, d(GCGAAGC) in solution: an extraordinarily stable structure resistant to nucleases and heat.

Hirao, I, Kawai, G, Yoshizawa, S, Nishimura, Y, Ishido, Y, Watanabe, K, ...

The three-dimensional structure of a short DNA fragment, d(GCGAAGC) exhibiting an extraordinarily stable hairpin structure was determined by nuclear magnetic resonance spectroscopy. Two possible...

Studies on nucleic acid interactions. I. Stabilities of mini-duplexes (dG2A4XA4G2-dC2T4YT4C2) and self-complementary d(GGGAAXYTTCCC) containing deoxyinosine and other mismatched bases.

Kawase, Y, Iwai, S, Inoue, H, Miura, K, Ohtsuka, E

The thermal stability of DNA duplexes containing deoxyinosine in a pairing position in turn with each of the four major deoxynucleotides has been investigated by measuring ultraviolet-absorbance at...

Molecular design of a eukaryotic messenger RNA and its chemical synthesis.

Iwase, R, Maeda, M, Fujiwara, T, Sekine, M, Hata, T, Miura, K

A designed mRNA consisting of 42 ribonucleotides having the cap structure was synthesized. The capped leader sequence of the brome mosaic virus (BMV) mRNA 4, m7G5'pppGUAUUAAUA (F-1), was synthesized...

Extraordinary stable structure of short single-stranded DNA fragments containing a specific base sequence: d(GCGAAAGC).

Hirao, I, Nishimura, Y, Naraoka, T, Watanabe, K, Arata, Y, Miura, K

Short single-stranded DNA fragments carrying a GCGAAAGC sequence were found to move unexpectedly faster than other fragments of the same length in electrophoresis on a polyacrylamide gel containing a...

Purification and characterization of two serine isoacceptor tRNAs from bovine mitochondria by using a hybridization assay method.

Yokogawa, T, Kumazawa, Y, Miura, K, Watanabe, K

For large scale preparation of mitochondrial tRNAs, a new hybridization assay method using synthetic oligodeoxyribonucleotide probes (16-17mer) complementary to individual tRNA sequences was...

Chemical synthesis of the 5'-terminal part bearing cap structure of messenger RNA of cytoplasmic polyhedrosis virus (CPV): m7G5'pppAmpG and m7G5'pppAmpGpU.

Yamaguchi, K, Nakagawa, I, Sekine, M, Hata, T, Shimotohno, K, Hiruta, M, ...

The 5'-terminal structures of mRNA bearing the so-called 'cap' from cytoplasmic polyhedrosis virus (CPV), m7G5' pppAmpG and m7G5' pppAmpGpU, were first chemically synthesized. S,S-Di(4-methoxyphenyl)...

Ozonolysis of supercoiled pBR322 DNA resulting in strand scission to open circular DNA.

Sawadaishi, K, Miura, K, Ohtsuka, E, Ueda, T, Ishizaki, K, Shinriki, N

Treatment of supercoiled pBR322 DNA with ozone resulted in the conversion of closed circular DNA to open circular DNA. Restriction analysis of the resulting open circular DNA showed that ozonolysis...

On the base-stacking in the 5'-terminal cap structure of mRNA: a fluorescence study.

Nishimura, Y, Takahashi, S, Yamamoto, T, Tsuboi, M, Hattori, M, Miura, K, ...

The fluorescence at 370 nm of the 7-methylguanosine residue (m7G) is found to be quenched when the base residue is involved in a stacking interaction with the adenosine residue in the cap structure...

Chemical modification of cytosine residues of U6 snRNA with hydrogen sulfide (nucleosides and nucleotides. Part 49 [1]).

Miura, K, Tsuda, S, Harada, F, Ueda, T

Sulfhydrolysis of cytosine residues to 4-thiouracil residues in mouse U6 snRNA was carried out to examine the secondary structure of U6 snRNA. The cytosine residues at positions 6, 42 and 68 were...

A novel cloverleaf structure found in mammalian mitochondrial tRNA(Ser) (UCN).

Yokogawa, T, Watanabe, Y, Kumazawa, Y, Ueda, T, Hirao, I, Miura, K, ...

Bovine mitochondrial tRNA(Ser) (UCN) has been thought to have two U-U mismatches at the top of the acceptor stem, as inferred from its gene sequence. However, this unusual structure has not been...

Higher-order structure of bovine mitochondrial tRNA(SerUGA): chemical modification and computer modeling.

Watanabe, Y, Kawai, G, Yokogawa, T, Hayashi, N, Kumazawa, Y, Ueda, T, ...

On the basis of enzymatic probing and phylogenetic comparison, we have previously proposed that mammalian mitochondrial tRNA(sSer) (anticodon UGA) possess a slightly altered cloverleaf structure in...

Extraordinarily stable mini-hairpins: electrophoretical and thermal properties of the various sequence variants of d(GCGAAAGC) and their effect on DNA sequencing.

Hirao, I, Nishimura, Y, Tagawa, Y, Watanabe, K, Miura, K

A small DNA fragment having a characteristic sequence d(GCGAAAGC) has been shown to form an extraordinarily stable mini-hairpin structure and to have an unusually rapid mobility in polyacrylamide gel...

The effects of a unique D-loop structure of a minor tRNA(UUALeu) from Streptomyces on its structural stability and amino acid accepting activity.

Ueda, Y, Kumagai, I, Miura, K

Streptomyces bldA gene, which encodes a tRNA corresponding to a very minor leucine codon, UUA, regulates pleiotropic gene expression which is involved in sporulation and secondary metabolism. The...

Role of the extra G-C pair at the end of the acceptor stem of tRNA(His) in aminoacylation.

Himeno, H, Hasegawa, T, Ueda, T, Watanabe, K, Miura, K, Shimizu, M

All sequenced histidine tRNAs have one additional nucleotide at the 5' end compared with other tRNA species. To investigate the role of this unique structure in aminoacylation, we constructed in...

Structure- and sequence-specificity of ozone degradation of supercoiled plasmid DNA.

Sawadaishi, K, Miura, K, Ohtsuka, E, Ueda, T, Shinriki, N, Ishizaki, K

Ozone-reactive sites on the nucleobase moieties in supercoiled pBR322 DNA were investigated by using sequencing procedures. Ozonolysis in the absence of salt resulted in degradation of thymine...

Relationship between structure of the 5' noncoding region of viral mRNA and efficiency in the initiation step of protein synthesis in a eukaryotic system.

Yamaguchi, K, Hidaka, S, Miura, K

To determine whether the rate of protein synthesis is controlled by the structure of mRNA near its 5' terminus, protein-synthesizing ability, especially in its initial stage, was compared among RNAs...

Comparative studies with various substrains of Mycobacterium bovis BCG on the production of an antigenic protein, MPB70.

Miura, K, Nagai, S, Kinomoto, M, Haga, S, Tokunaga, T

A protein, isolated and purified from the unheated culture filtrate of Mycobacterium bovis BCG (substrain Tokyo 172) and designated MPB70, elicited a delayed skin reaction in guinea pigs sensitized...

c-Ha-ras down regulates the alpha-fetoprotein gene but not the albumin gene in human hepatoma cells.

Nakao, K, Lawless, D, Ohe, Y, Miyao, Y, Nakabayashi, H, Kamiya, H, ...

We studied the effects of transfection of the normal c-Ha-ras gene, rasGly-12, and its oncogenic mutant, rasVal-12, on expression of the alpha-fetoprotein (AFP) and albumin genes in a human hepatoma...

Double-stranded Ribonucleic Acid from Cytoplasmic Polyhedrosis Virus of the Silkworm

Miura, K., Fujii, I., Sakaki, T., Fuke, M., Kawase, S.

Ribonucleic acid (RNA) was extracted by phenol treatment from cytoplasmic polyhedrosis virus isolated from the midgut of infected silkworms. This RNA appears as threads when precipitated in alcohol....

Similarity of nucleotide sequences around the origin of DNA replication in mouse polyoma virus and simian virus 40.

Soeda, E, Kimura, G, Miura, K

The nucleotide sequence around the origin of replication in DNA of mouse polyoma virus was determined by 32P labeling of the 3' terminus of the Hap II-5/Alu I-1 DNA fragment, with the use of DNA...

N-WASP, a novel actin-depolymerizing protein, regulates the cortical cytoskeletal rearrangement in a PIP2-dependent manner downstream of tyrosine kinases.

Miki, H, Miura, K, Takenawa, T

Here we identify a 65 kDa protein (N-WASP) from brain that binds the SH3 domains of Ash/Grb2. The sequence is homologous to Wiskott-Aldrich syndrome protein (WASP). N-WASP has several functional...

Nuclease resistance of an extraordinarily thermostable mini-hairpin DNA fragment, d(GCGAAGC) and its application to in vitro protein synthesis.

Yoshizawa, S, Ueda, T, Ishido, Y, Miura, K, Watanabe, K, Hirao, I

The nuclease resistance of a short, thermostable mini-hairpin, d(GCGAAGC), and other related hairpins was examined. Hairpins possessing a purine-rich (GAA) or (GAAA) loop appeared to be more...

A major role for phospholipase A2 in antigen-induced arachidonic acid release in rat mast cells.

Yamada, K, Okano, Y, Miura, K, Nozawa, Y

Cross-linking of IgE receptors by antigen stimulation leads to histamine release and arachidonic acid release in rat peritoneal mast cells. Investigators have reported a diverse distribution of...

Interaction of Ash/Grb-2 via its SH3 domains with neuron-specific p150 and p65.

Miura, K, Miki, H, Shimazaki, K, Kawai, N, Takenawa, T

We found that 180 kDa, 150 kDa (p150), 110 kDa, 100 kDa and 65 kDa (p65) proteins comprise the major Ash/Grb-2-binding proteins in bovine brain. Among these proteins, 180 kDa and 100 kDa proteins...

Methylation Imprinting of H19 and SNRPN Genes in Human Benign Ovarian Teratomas

Miura, K., Obama, M., Yun, K., Masuzaki, H., Ikeda, Y., Yoshimura, S., ...

In humans, studies of female germ cells are very limited by ethics. The current study investigated the usefulness of benign ovarian teratomas as a substitute for ova in analyses of imprinted genes....

Effect of the higher-order structure of tRNAs on the stability of hybrids with oligodeoxyribonucleotides: separation of tRNA by an efficient solution hybridization.

Kumazawa, Y, Yokogawa, T, Tsurui, H, Miura, K, Watanabe, K

In the course of developing a method to purify a single tRNA species efficiently, we have examined hybridization efficiencies between some tRNAs and short oligodeoxyribonucleotide probes both by the...

Establishment and characterization of methylmercury-resistant PC12 cell line.

Miura, K, Clarkson, T W, Ikeda, K, Naganuma, A, Imura, N

Methylmercury (MeHg)-resistant sublines of rat pheochromocytoma (PC12) cells were isolated by repeated exposure to stepwise increased concentrations of MeHg. One of the sublines (PC12/TM) showed an...

Crystal structure of an engineered subtilisin inhibitor complexed with bovine trypsin.

Takeuchi, Y, Nonaka, T, Nakamura, K T, Kojima, S, Miura, K, Mitsui, Y

Proteinase specificity of a proteinaceous inhibitor of subtilisin (SSI; Streptomyces subtilisin inhibitor) can be altered so as to strongly inhibit trypsin simply by replacing P1 methionine with...

Functional conversion of the homologous proteins alpha-lactalbumin and lysozyme by exon exchange.

Kumagai, I, Takeda, S, Miura, K

Exons of eukaryotic genes that encode proteins frequently appear to encode structural and/or functional protein units [Gilbert, W. (1978) Nature (London) 271, 501; Blake, C.C.F. (1979) Nature...

Streptomyces serine protease (SAM-P20): recombinant production, characterization, and interaction with endogenous protease inhibitor.

Taguchi, S, Suzuki, M, Kojima, S, Miura, K, Momose, H

Previously, we isolated a candidate for an endogenous target enzyme(s) of the Streptomyces subtilisin inhibitor (SSI), termed SAM-P20, from a non-SSI-producing mutant strain (S. Taguchi, A. Odaka, Y....

Streptomyces subtilisin inhibitor-like proteins are distributed widely in streptomycetes.

Taguchi, S, Kikuchi, H, Suzuki, M, Kojima, S, Terabe, M, Miura, K, ...

Streptomyces subtilisin inhibitor-like proteins were found to be distributed widely in streptomycetes by using the combination of the convenient, newly developed plate assay system and an established...

Phosphatidylinositol 4,5-bisphosphate phosphatase regulates the rearrangement of actin filaments.

Sakisaka, T, Itoh, T, Miura, K, Takenawa, T

Phosphatidylinositol 4,5-bisphosphate (PIP2) reorganizes actin filaments by modulating the functions of a variety of actin-regulatory proteins. Until now, it was thought that bound PIP2 is hydrolyzed...

Lack of correlation between interferon production of mononuclear cells and virus replication in chronic hepatitis B virus infection.

Kinoshita, R, Miura, K, Suzuki, S, Uchino, H

Interferon production in hepatitis B virus carriers with normal liver functions was preserved, whereas in carriers with chronic hepatitis it was depressed. The lower interferon production in...

Synthesis and hybridization studies on two complementary nona(2'-O-methyl)ribonucleotides.

Inoue, H, Hayase, Y, Imura, A, Iwai, S, Miura, K, Ohtsuka, E

2'-O-Methyl derivatives of the common ribonucleosides except for guanosine were synthesized via the 2'-O-methylation of appropriately-protected nucleosides with CH3I in the presence of Ag2O. The...

Unusual anticodon loop structure found in E.coli lysine tRNA.

Watanabe, K, Hayashi, N, Oyama, A, Nishikawa, K, Ueda, T, Miura, K

Although both tRNA(Lys) and tRNA(Glu) of E. coli possess similar anticodon loop sequences, with the same hypermodified nucleoside 5-methylaminomethyl-2-thiouridine (mnm5s2U) at the first position of...

Most compact hairpin-turn structure exerted by a short DNA fragment, d(GCGAAGC) in solution: an extraordinarily stable structure resistant to nucleases and heat.

Hirao, I, Kawai, G, Yoshizawa, S, Nishimura, Y, Ishido, Y, Watanabe, K, ...

The three-dimensional structure of a short DNA fragment, d(GCGAAGC) exhibiting an extraordinarily stable hairpin structure was determined by nuclear magnetic resonance spectroscopy. Two possible...

Studies on nucleic acid interactions. I. Stabilities of mini-duplexes (dG2A4XA4G2-dC2T4YT4C2) and self-complementary d(GGGAAXYTTCCC) containing deoxyinosine and other mismatched bases.

Kawase, Y, Iwai, S, Inoue, H, Miura, K, Ohtsuka, E

The thermal stability of DNA duplexes containing deoxyinosine in a pairing position in turn with each of the four major deoxynucleotides has been investigated by measuring ultraviolet-absorbance at...

Molecular design of a eukaryotic messenger RNA and its chemical synthesis.

Iwase, R, Maeda, M, Fujiwara, T, Sekine, M, Hata, T, Miura, K

A designed mRNA consisting of 42 ribonucleotides having the cap structure was synthesized. The capped leader sequence of the brome mosaic virus (BMV) mRNA 4, m7G5'pppGUAUUAAUA (F-1), was synthesized...

Effect of the higher-order structure of tRNAs on the stability of hybrids with oligodeoxyribonucleotides: separation of tRNA by an efficient solution hybridization.

Kumazawa, Y, Yokogawa, T, Tsurui, H, Miura, K, Watanabe, K

In the course of developing a method to purify a single tRNA species efficiently, we have examined hybridization efficiencies between some tRNAs and short oligodeoxyribonucleotide probes both by the...

Extraordinary stable structure of short single-stranded DNA fragments containing a specific base sequence: d(GCGAAAGC).

Hirao, I, Nishimura, Y, Naraoka, T, Watanabe, K, Arata, Y, Miura, K

Short single-stranded DNA fragments carrying a GCGAAAGC sequence were found to move unexpectedly faster than other fragments of the same length in electrophoresis on a polyacrylamide gel containing a...

Purification and characterization of two serine isoacceptor tRNAs from bovine mitochondria by using a hybridization assay method.

Yokogawa, T, Kumazawa, Y, Miura, K, Watanabe, K

For large scale preparation of mitochondrial tRNAs, a new hybridization assay method using synthetic oligodeoxyribonucleotide probes (16-17mer) complementary to individual tRNA sequences was...

Chemical synthesis of the 5'-terminal part bearing cap structure of messenger RNA of cytoplasmic polyhedrosis virus (CPV): m7G5'pppAmpG and m7G5'pppAmpGpU.

Yamaguchi, K, Nakagawa, I, Sekine, M, Hata, T, Shimotohno, K, Hiruta, M, ...

The 5'-terminal structures of mRNA bearing the so-called 'cap' from cytoplasmic polyhedrosis virus (CPV), m7G5' pppAmpG and m7G5' pppAmpGpU, were first chemically synthesized. S,S-Di(4-methoxyphenyl)...

Ozonolysis of supercoiled pBR322 DNA resulting in strand scission to open circular DNA.

Sawadaishi, K, Miura, K, Ohtsuka, E, Ueda, T, Ishizaki, K, Shinriki, N

Treatment of supercoiled pBR322 DNA with ozone resulted in the conversion of closed circular DNA to open circular DNA. Restriction analysis of the resulting open circular DNA showed that ozonolysis...

On the base-stacking in the 5'-terminal cap structure of mRNA: a fluorescence study.

Nishimura, Y, Takahashi, S, Yamamoto, T, Tsuboi, M, Hattori, M, Miura, K, ...

The fluorescence at 370 nm of the 7-methylguanosine residue (m7G) is found to be quenched when the base residue is involved in a stacking interaction with the adenosine residue in the cap structure...

Chemical modification of cytosine residues of U6 snRNA with hydrogen sulfide (nucleosides and nucleotides. Part 49 [1]).

Miura, K, Tsuda, S, Harada, F, Ueda, T

Sulfhydrolysis of cytosine residues to 4-thiouracil residues in mouse U6 snRNA was carried out to examine the secondary structure of U6 snRNA. The cytosine residues at positions 6, 42 and 68 were...

A novel cloverleaf structure found in mammalian mitochondrial tRNA(Ser) (UCN).

Yokogawa, T, Watanabe, Y, Kumazawa, Y, Ueda, T, Hirao, I, Miura, K, ...

Bovine mitochondrial tRNA(Ser) (UCN) has been thought to have two U-U mismatches at the top of the acceptor stem, as inferred from its gene sequence. However, this unusual structure has not been...

Higher-order structure of bovine mitochondrial tRNA(SerUGA): chemical modification and computer modeling.

Watanabe, Y, Kawai, G, Yokogawa, T, Hayashi, N, Kumazawa, Y, Ueda, T, ...

On the basis of enzymatic probing and phylogenetic comparison, we have previously proposed that mammalian mitochondrial tRNA(sSer) (anticodon UGA) possess a slightly altered cloverleaf structure in...

Extraordinarily stable mini-hairpins: electrophoretical and thermal properties of the various sequence variants of d(GCGAAAGC) and their effect on DNA sequencing.

Hirao, I, Nishimura, Y, Tagawa, Y, Watanabe, K, Miura, K

A small DNA fragment having a characteristic sequence d(GCGAAAGC) has been shown to form an extraordinarily stable mini-hairpin structure and to have an unusually rapid mobility in polyacrylamide gel...

The effects of a unique D-loop structure of a minor tRNA(UUALeu) from Streptomyces on its structural stability and amino acid accepting activity.

Ueda, Y, Kumagai, I, Miura, K

Streptomyces bldA gene, which encodes a tRNA corresponding to a very minor leucine codon, UUA, regulates pleiotropic gene expression which is involved in sporulation and secondary metabolism. The...

Role of the extra G-C pair at the end of the acceptor stem of tRNA(His) in aminoacylation.

Himeno, H, Hasegawa, T, Ueda, T, Watanabe, K, Miura, K, Shimizu, M

All sequenced histidine tRNAs have one additional nucleotide at the 5' end compared with other tRNA species. To investigate the role of this unique structure in aminoacylation, we constructed in...

Structure- and sequence-specificity of ozone degradation of supercoiled plasmid DNA.

Sawadaishi, K, Miura, K, Ohtsuka, E, Ueda, T, Shinriki, N, Ishizaki, K

Ozone-reactive sites on the nucleobase moieties in supercoiled pBR322 DNA were investigated by using sequencing procedures. Ozonolysis in the absence of salt resulted in degradation of thymine...

Relationship between structure of the 5' noncoding region of viral mRNA and efficiency in the initiation step of protein synthesis in a eukaryotic system.

Yamaguchi, K, Hidaka, S, Miura, K

To determine whether the rate of protein synthesis is controlled by the structure of mRNA near its 5' terminus, protein-synthesizing ability, especially in its initial stage, was compared among RNAs...

Comparative studies with various substrains of Mycobacterium bovis BCG on the production of an antigenic protein, MPB70.

Miura, K, Nagai, S, Kinomoto, M, Haga, S, Tokunaga, T

A protein, isolated and purified from the unheated culture filtrate of Mycobacterium bovis BCG (substrain Tokyo 172) and designated MPB70, elicited a delayed skin reaction in guinea pigs sensitized...

c-Ha-ras down regulates the alpha-fetoprotein gene but not the albumin gene in human hepatoma cells.

Nakao, K, Lawless, D, Ohe, Y, Miyao, Y, Nakabayashi, H, Kamiya, H, ...

We studied the effects of transfection of the normal c-Ha-ras gene, rasGly-12, and its oncogenic mutant, rasVal-12, on expression of the alpha-fetoprotein (AFP) and albumin genes in a human hepatoma...

Double-stranded Ribonucleic Acid from Cytoplasmic Polyhedrosis Virus of the Silkworm

Miura, K., Fujii, I., Sakaki, T., Fuke, M., Kawase, S.

Ribonucleic acid (RNA) was extracted by phenol treatment from cytoplasmic polyhedrosis virus isolated from the midgut of infected silkworms. This RNA appears as threads when precipitated in alcohol....

Similarity of nucleotide sequences around the origin of DNA replication in mouse polyoma virus and simian virus 40.

Soeda, E, Kimura, G, Miura, K

The nucleotide sequence around the origin of replication in DNA of mouse polyoma virus was determined by 32P labeling of the 3' terminus of the Hap II-5/Alu I-1 DNA fragment, with the use of DNA...

N-WASP, a novel actin-depolymerizing protein, regulates the cortical cytoskeletal rearrangement in a PIP2-dependent manner downstream of tyrosine kinases.

Miki, H, Miura, K, Takenawa, T

Here we identify a 65 kDa protein (N-WASP) from brain that binds the SH3 domains of Ash/Grb2. The sequence is homologous to Wiskott-Aldrich syndrome protein (WASP). N-WASP has several functional...

Nuclease resistance of an extraordinarily thermostable mini-hairpin DNA fragment, d(GCGAAGC) and its application to in vitro protein synthesis.

Yoshizawa, S, Ueda, T, Ishido, Y, Miura, K, Watanabe, K, Hirao, I

The nuclease resistance of a short, thermostable mini-hairpin, d(GCGAAGC), and other related hairpins was examined. Hairpins possessing a purine-rich (GAA) or (GAAA) loop appeared to be more...

A major role for phospholipase A2 in antigen-induced arachidonic acid release in rat mast cells.

Yamada, K, Okano, Y, Miura, K, Nozawa, Y

Cross-linking of IgE receptors by antigen stimulation leads to histamine release and arachidonic acid release in rat peritoneal mast cells. Investigators have reported a diverse distribution of...

Interaction of Ash/Grb-2 via its SH3 domains with neuron-specific p150 and p65.

Miura, K, Miki, H, Shimazaki, K, Kawai, N, Takenawa, T

We found that 180 kDa, 150 kDa (p150), 110 kDa, 100 kDa and 65 kDa (p65) proteins comprise the major Ash/Grb-2-binding proteins in bovine brain. Among these proteins, 180 kDa and 100 kDa proteins...

Methylation Imprinting of H19 and SNRPN Genes in Human Benign Ovarian Teratomas

Miura, K., Obama, M., Yun, K., Masuzaki, H., Ikeda, Y., Yoshimura, S., ...

In humans, studies of female germ cells are very limited by ethics. The current study investigated the usefulness of benign ovarian teratomas as a substitute for ova in analyses of imprinted genes....

Establishment and characterization of methylmercury-resistant PC12 cell line.

Miura, K, Clarkson, T W, Ikeda, K, Naganuma, A, Imura, N

Methylmercury (MeHg)-resistant sublines of rat pheochromocytoma (PC12) cells were isolated by repeated exposure to stepwise increased concentrations of MeHg. One of the sublines (PC12/TM) showed an...

Lymphocyte chemotaxis in inflammation. VI. Lyt phenotype analysis of effector cells responsible for producing murine lymphocyte chemotactic factor.

Shimokawa, Y, Miura, K, Hifumi, M, Hayashi, H

Murine lymphocyte chemotactic factor (LCF) was demonstrated in various culture fluids of C3H/HeN lymphoid cells stimulated with specific soluble protein antigen, mitogen or alloantigenic cells....

Selective chemotaxis of Ia antigen-positive macrophages by macrophage chemotactic lymphokine produced by concanavalin A stimulation.

Miura, K, Honda, M, Yoshimura, T, Hayashi, H

M1- cells (leukaemic cell line cells established from SL/Am mouse), Mm1 cells (macrophage-like cells subcloned from M1- cells), and undifferentiated B24 cells (subcloned from M1- cells) were...

Epidemiology of idiopathic cardiomyopathy in Japan: results from a nationwide survey

Miura, K, Nakagawa, H, Morikawa, Y, Sasayama, S, Matsumori, A, Hasegawa, K, ...

Objective: To estimate the total number of patients with idiopathic cardiomyopathy in Japan and the prevalence of the disorder.

Recombination activating genes (RAG) induce secondary Ig gene rearrangement in and subsequent apoptosis of human peripheral blood circulating B lymphocytes

NAGAFUCHI, H, YOSHIKAWA, H, TAKEBA, Y, NARA, K, MIURA, K, KUROKAWA, M S, ...

Recombination activating gene (RAG) re-expression and secondary Ig gene rearrangement in mature B lymphocytes have been reported. Here, we have studied RAG expression of peripheral blood B...

AT1 receptor-mediated stimulation by angiotensin II of rat aortic fibronectin gene expression in vivo.

Kim, S, Ohta, K, Hamaguchi, A, Omura, T, Tominaga, K, Yukimura, T, ...

Fibronectin plays an important role in various vascular diseases. A subpressor (200 ng kg-1 min-1) or pressor (1000 ng kg-1 min-1) dose of angiotensin II was continuously infused into rats by osmotic...

Attenuation of adrenomedullin-induced renal vasodilatation by NG-nitro L-arginine but not glibenclamide.

Miura, K., Ebara, T., Okumura, M., Matsuura, T., Kim, S., Yukimura, T., ...

1. The present study was conducted in order to elucidate the in vivo contribution of nitric oxide (NO) and the glibenclamide-sensitive potassium channel in the renal action of adrenomedullin in...

Effects of an AT1 receptor antagonist, an ACE inhibitor and a calcium channel antagonist on cardiac gene expressions in hypertensive rats.

Kim, S., Ohta, K., Hamaguchi, A., Yukimura, T., Miura, K., Iwao, H.

1. This study was undertaken to determine whether the AT1 receptor directly contributes to hypertension-induced cardiac hypertrophy and gene expressions. 2. Stroke-prone spontaneously hypertensive...

A case of sinus arrest caused by opening the mouth under general anesthesia.

Seo, K., Takayama, H., Araya, Y., Miura, K., Someya, G.

We report a case in which transient sinus arrest was observed under general anesthesia. This was associated with opening the mouth and was thought to be caused by a trigeminovagal reflex. The reflex...

Electromagnetic interference of an external temporary pacemaker during maxillofacial and neck surgery.

Seo, K., Takayama, H., Araya, Y., Miura, K., Tanaka, Y., Kobayashi, Y., ...

Indirect inhibition of an external temporary pacemaker by electrocautery is reported. Before induction of general anesthesia for a hemimaxillectomy and radical neck dissection, a temporary...

Effect of the platelet-activating factor antagonist, TCV-309, and the cyclo-oxygenase inhibitor, ibuprofen, on the haemodynamic changes in canine experimental endotoxic shock.

Yamanaka, S., Iwao, H., Yukimura, T., Kim, S., Miura, K.

1. The present study was conducted in order to examine the effects of the platelet-activating factor (PAF) antagonist, TCV-309, and the cyclo-oxygenase inhibitor, ibuprofen, on the acute haemodynamic...

Mortality of inhabitants in an area polluted by cadmium: 15 year follow up.

Nishijo, M, Nakagawa, H, Morikawa, Y, Tabata, M, Senma, M, Miura, K, ...

OBJECTIVE--To assess the influence of environmental exposure to cadmium (Cd) on long term outcome of inhabitants living in an area polluted by Cd. METHODS--A follow up study for 15 years (from 1974-5...

Involvement of Epstein-Barr virus latent membrane protein 1 in disease progression in patients with idiopathic pulmonary fibrosis

Tsukamoto, K, Hayakawa, H, Sato, A, Chida, K, Nakamura, H, Miura, K

BACKGROUND—The role of Epstein-Barr virus (EBV) in idiopathic pulmonary fibrosis (IPF) is uncertain. A study was undertaken to detect the virus in IPF as well as to clarify the influence of EBV on...

Interleukin-6 cDNA transfected Lewis lung carcinoma cells show unaltered net tumour growth rate but cause weight loss and shortened survival in syngeneic mice.

Ohe, Y., Podack, E. R., Olsen, K. J., Miyahara, Y., Miura, K., Saito, H., ...

HuIL-6 cDNA, cloned into a neomycin resistant conferring expression vector, BMGNeo, was transfected into Lewis Lung Carcinoma (LLC) cells. LLC cells (5 x 10(6) ml-1) transfected with IL-6 cDNA...

Glycosaminoglycan content and synthesis in gastric carcinoma.

Sobue, M., Takeuchi, J., Miura, K., Kawase, K., Mizuno, F., Sato, E.

The glycosaminoglycan (GAG) content of stomach carcinoma tissue was compared with that of non-neoplastic mucosa. GAG synthesis was also studied, by an analysis of 35S-labelled material after...

Prognostic value of vascular endothelial growth factor (VEGF) in head and neck squamous cell carcinomas

Mineta, H, Miura, K, Ogino, T, Takebayashi, S, Misawa, K, Ueda, Y, ...

Vascular endothelial growth factor (VEGF) has been identified as the substance that increases the permeability and proliferation of vascular endothelial cells. We examined the clinical significance...

The Initial Disparity Vergence Elicited With Single and Dual Grating Stimuli in Monkeys: Evidence for Disparity Energy Sensing and Nonlinear Interactions

Miura, K., Sugita, Y., Matsuura, K., Inaba, N., Kawano, K., Miles, F. A.

We recorded the initial vertical vergence eye movements elicited in monkeys at short latency (∼70 ms) when the two eyes see one-dimensional (1D) horizontal grating patterns that are identical...