K. Mizuno

Publication List Details

Period

1983 - 9999

Number

94

Co-Authors

Annual and Interannual Variability in the Kuroshio Current System, (9999)

Mizuno,K., White,W. B.

Individual, seasonal, 300-m temperature maps were constructed over the Kuroshio Current System from 130 E to 170 W, for a four-year period from summer 1976 through spring 1980, by using TRANSPAC XBT...

ABSTRACTS (2009)

Abdelwahab, A., Gardner, M., Parkash, R., Basta, M., Sapp, J., Veltmann, C., ...

Introduction: Scar-related ventricular tachycardia (VT) is often unmappable. Data regarding the outcomes of ablation for mappable vs unmappable VT are lacking. Methods: Catheter ablation of...

Mismo field experiment in the equatorial Indian Ocean (2008)

Masumoto, Y., Kuroda, Y., Katsumata, M., Mizuno, K., Takayabu, Y.N., Yoshizaki, M., ...

The Mirai Indian Ocean cruise for the Study of the Madden–Julian oscillation (MJO)-convection Onset (MISMO) was a field experiment that took place in the central equatorial Indian Ocean during...

Transient decreases in Bispectral Index without associated changes in the level of consciousness during photic stimulation in an epileptic patient (2007)

Ohshima, N., Chinzei, M., Mizuno, K., Hayashida, M., Kitamura, T., Shibuya, H., ...

This case report describes a patient with a history of epileptic seizures who showed unusual decreases in the Bispectral Index (BIS) attributable to the induction of abnormal slow...

Study of blind thrust faults underlying Tokyo and Osaka urban areas using a combination of high-resolution seismic reflection profiling and continuous coring (2003)

Sugiyama, Y., Mizuno, K., Nanayama, F., Sugai, T., Yokota, H., Hosoya, T., ...

We acquired high-resolution seismic reflection profiles and continuously cored boreholes to evaluate active flexures produced by major blind thrust fault systems within two densely populated...

Transition of electron heating mode in a planar microwave discharge at low pressures (2000)

Sugai, H., Ghanashev, I., Mizuno, K.

Spatial distributions of electron density n_e , electron temperature T_e , and wave field intensity in a planar microwave discharge at low pressures (10–100 mTorr) are measured with the discharge...

CORRIGENDUM: PCR analysis of the Y chromosome long arm in azoospermic patients: evidence for a second locus required for spermatogenesis (1995)

Kobayashi, K., Mizuno, K., Hida, A., Komaki, R., Tomita, K., Matsushita, I., ...

The authors wish to correct an error in the sequence of one of the primers for the YRRMI locus. A letter A is missing from the Fl9 primer sequence, the correct sequence being: F19,...

DOUBLE FERROMAGNETISM IN SINGLE CRYSTAL Gd0.75Y0.175Sc0.075 ALLOY (1988)

Ito, T., Mizuno, K., Ito, K., Beaudry, B.

Magnetization, electrical resistivity, thermal expansion and specific heat measurements on Gd0.75Y0.175Sc0.075 single crystal show two anomalies at the transition temperatures and two different...

DOUBLE FERROMAGNETISM IN SINGLE CRYSTAL Gd0.75Y0.175Sc0.075 ALLOY (1988)

Ito, T., Mizuno, K., Ito, K., Beaudry, B.

Magnetization, electrical resistivity, thermal expansion and specific heat measurements on Gd0.75Y0.175Sc0.075 single crystal show two anomalies at the transition temperatures and two different...

DOUBLE FERROMAGNETISM IN SINGLE CRYSTAL Gd0.75Y0.175Sc0.075 ALLOY (1988)

Ito, T., Mizuno, K., Ito, K., Beaudry, B.

Magnetization, electrical resistivity, thermal expansion and specific heat measurements on Gd0.75Y0.175Sc0.075 single crystal show two anomalies at the transition temperatures and two different...

ANISOTROPY OF ENERGY GAP IN SUPERCONDUCTING ALUMINUM (1985)

Kogure, Y., Takeuchi, N., Hiki, Y., Mizuno, K., Kino, T.

The attenuation of 10 MHz ultrasound in aluminum single crystals of high purity (99.9999 %) with the [100], [110], and [111] orientations has been measured in the temperature range 0.4 - 1.2 K. The...

EXCITON DYNAMICS IN ORGANIC MOLECULAR CRYSTALS (1985)

Matsui, A., Mizuno, K., Kobayashi, M.

Dynamical behavior of Frenkel excitons in aromatic hydrocarbon crystals, pyrene, α-perylene, β-perylene, and tetracene are overviewed based on the published references and in terms of the...

ANISOTROPY OF ENERGY GAP IN SUPERCONDUCTING ALUMINUM (1985)

Kogure, Y., Takeuchi, N., Hiki, Y., Mizuno, K., Kino, T.

The attenuation of 10 MHz ultrasound in aluminum single crystals of high purity (99.9999 %) with the [100], [110], and [111] orientations has been measured in the temperature range 0.4 - 1.2 K. The...

EXCITON DYNAMICS IN ORGANIC MOLECULAR CRYSTALS (1985)

Matsui, A., Mizuno, K., Kobayashi, M.

Dynamical behavior of Frenkel excitons in aromatic hydrocarbon crystals, pyrene, α-perylene, β-perylene, and tetracene are overviewed based on the published references and in terms of the...

ANISOTROPY OF ENERGY GAP IN SUPERCONDUCTING ALUMINUM (1985)

Kogure, Y., Takeuchi, N., Hiki, Y., Mizuno, K., Kino, T.

The attenuation of 10 MHz ultrasound in aluminum single crystals of high purity (99.9999 %) with the [100], [110], and [111] orientations has been measured in the temperature range 0.4 - 1.2 K. The...

EXCITON DYNAMICS IN ORGANIC MOLECULAR CRYSTALS (1985)

Matsui, A., Mizuno, K., Kobayashi, M.

Dynamical behavior of Frenkel excitons in aromatic hydrocarbon crystals, pyrene, α-perylene, β-perylene, and tetracene are overviewed based on the published references and in terms of the...

TEMPERATURE DEPENDENCE OF NMR T1 AND χ IN Br3, AsF6-DOPED (CH)x (1983)

Kume, K., Mizuno, K., Mizoguchi, K., Nomura, K., Takayama, H., Ishihara, S., ...

We have measured the temperature dependence of proton NMR T1 and Pauli paramagnetic susceptibility χp in Br3- and AsF6-doped (CH)x. The microscopic conductivity σNMR has been calculated...

TEMPERATURE DEPENDENCE OF NMR T1 AND χ IN Br3, AsF6-DOPED (CH)x (1983)

Kume, K., Mizuno, K., Mizoguchi, K., Nomura, K., Takayama, H., Ishihara, S., ...

We have measured the temperature dependence of proton NMR T1 and Pauli paramagnetic susceptibility χp in Br3- and AsF6-doped (CH)x. The microscopic conductivity σNMR has been calculated...

TEMPERATURE DEPENDENCE OF NMR T1 AND χ IN Br3, AsF6-DOPED (CH)x (1983)

Kume, K., Mizuno, K., Mizoguchi, K., Nomura, K., Takayama, H., Ishihara, S., ...

We have measured the temperature dependence of proton NMR T1 and Pauli paramagnetic susceptibility χp in Br3- and AsF6-doped (CH)x. The microscopic conductivity σNMR has been calculated...

Platelet-derived growth factor activates protein kinase C epsilon through redundant and independent signaling pathways involving phospholipase C gamma or phosphatidylinositol 3-kinase.

Moriya, S, Kazlauskas, A, Akimoto, K, Hirai, S, Mizuno, K, Takenawa, T, ...

Protein kinase C (PKC), a major cellular receptor for tumor-promoting phorbol esters and diacylglycerols (DGs), appears to be involved in a variety of cellular functions, although its activation...

Direct effect of basic fibroblast growth factor on gene transcription in a cell-free system.

Nakanishi, Y, Kihara, K, Mizuno, K, Masamune, Y, Yoshitake, Y, Nishikawa, K

Recent findings on the translocation of intact fibroblast growth factor (FGF) into the cell nucleus suggest that it functions directly in nuclear events. We examined the effect of human basic FGF...

Coordinated Regulation of the Genes Participating in Starch Biosynthesis by the Rice Floury-2 Locus.

Kawasaki, T., Mizuno, K., Shimada, H., Satoh, H., Kishimoto, N., Okumura, S., ...

The recessive floury-2 (flo-2) locus of rice (Oryza sativa L.), which is located on chromosome 4, causes a strong reduction in expression of the gene encoding an isoform of branching enzyme RBE1 in...

Identification, cDNA cloning, and gene expression of soluble starch synthase in rice (Oryza sativa L.) immature seeds.

Baba, T, Nishihara, M, Mizuno, K, Kawasaki, T, Shimada, H, Kobayashi, E, ...

Three forms of soluble starch synthase were resolved by anion-exchange chromatography of soluble extracts from immature rice (Oryza sativa L.) seeds, and each of these forms was further purified by...

Genetic control of the immune responsiveness to Streptococcus mutans by the major histocompatibility complex of the rat (RT1).

Niiyama, T, Kojima, H, Mizuno, K, Matsuno, Y, Fujii, H, Misonou, J, ...

The lymph node cells from 11 strains of rats, differing in the genotype of the major histocompatibility complex of the rat (RT1), were examined on the basis of their proliferative response to the...

Susceptibility of hepatitis B virus to disinfectants or heat.

Kobayashi, H, Tsuzuki, M, Koshimizu, K, Toyama, H, Yoshihara, N, Shikata, T, ...

Using direct chimpanzee inoculation as an assay method, we tested the abilities of the following chemical or physical treatments to inactivate hepatitis B virus in human plasma: 1% aqueous...

Presence of renin secretory granules in rat adrenal gland and stimulation of renin secretion by angiotensin II but not by adrenocorticotropin.

Mizuno, K, Hoffman, L H, McKenzie, J C, Inagami, T

Renin has been identified biochemically and immunohistochemically in the adrenal gland. We examined the subcellular distribution and behavior of adrenal renin. By differential centrifugation of...

A cDNA clone closely associated with non-A, non-B hepatitis.

Maéno, M, Kaminaka, K, Sugimoto, H, Esumi, M, Hayashi, N, Komatsu, K, ...

A lambda gt11 cDNA library was constructed from RNA purified from hepatitis B viral surface antigen-negative human plasma with high alanine aminotransferase activity. A cDNA clone, designated as...

MPTP delta, a putative murine homolog of HPTP delta, is expressed in specialized regions of the brain and in the B-cell lineage.

Mizuno, K, Hasegawa, K, Katagiri, T, Ogimoto, M, Ichikawa, T, Yakura, H

Protein tyrosine phosphatases (PTPs), together with protein tyrosine kinases (PTKs), are involved in the regulation of cell activation, growth, and differentiation. To further elucidate the fine...

A new member of the protein kinase C family, nPKC theta, predominantly expressed in skeletal muscle.

Osada, S, Mizuno, K, Saido, T C, Suzuki, K, Kuroki, T, Ohno, S

A new protein kinase C (PKC)-related cDNA with unique tissue distribution has been isolated and characterized. This cDNA encodes a protein, nPKC theta, which consists of 707 amino acid residues and...

Tumorigenicity of the met proto-oncogene and the gene for hepatocyte growth factor.

Rong, S, Bodescot, M, Blair, D, Dunn, J, Nakamura, T, Mizuno, K, ...

The met proto-oncogene is the tyrosine kinase growth factor receptor for hepatocyte growth factor/scatter factor (HGF/SF). It was previously shown that, like the oncogenic tpr-met, the mouse met...

Thyroid-specific enhancer-binding protein (T/EBP): cDNA cloning, functional characterization, and structural identity with thyroid transcription factor TTF-1.

Mizuno, K, Gonzalez, F J, Kimura, S

A cDNA clone encoding a thyroid-specific enhancer-binding protein (T/EBP) was isolated from a rat thyroid-derived FRTL-5 cell lambda gt 11 expression library, using a double-stranded oligonucleotide...

A small nuclear RNA, U5, can transform cells in vitro.

Hamada, K, Kumazaki, T, Mizuno, K, Yokoro, K

Low-molecular-weight RNA exhibiting transforming potential was identified in chemically induced lymphoma cells by the transformation of mink lung cells after transfection. The RNA was sequenced by...

Ras-dependent signal transduction is indispensable but not sufficient for the activation of AP1/Jun by PKC delta.

Hirai, S, Izumi, Y, Higa, K, Kaibuchi, K, Mizuno, K, Osada, S, ...

Modulation of gene expression by 12-O-tetradecanoylphorbol-13-acetate (TPA) is thought to be mediated by protein kinase C (PKC), a major cellular receptor for TPA. We confirm this by showing that the...

EGF or PDGF receptors activate atypical PKClambda through phosphatidylinositol 3-kinase.

Akimoto, K, Takahashi, R, Moriya, S, Nishioka, N, Takayanagi, J, Kimura, K, ...

Overexpression of a TPA-insensitive PKC member, an atypical protein kinase C (aPKClambda), results in an enhancement of the transcriptional activation of TPA response element (TRE) in cells...

Nuclear export of LIM-kinase 1, mediated by two leucine-rich nuclear-export signals within the PDZ domain.

Yang, N, Mizuno, K

LIM-kinase 1 (LIMK1) is a serine/threonine kinase that phosphorylates cofilin and regulates actin-filament dynamics. LIMK1, which contains two LIM domains and a single PDZ domain, localizes...

The N-terminal LIM domain negatively regulates the kinase activity of LIM-kinase 1.

Nagata, K, Ohashi, K, Yang, N, Mizuno, K

LIM-kinase 1 (LIMK1, where LIM is an acronym of the three gene products Lin-11, Isl-1 and Mec-3) is a serine/threonine kinase that phosphorylates cofilin and regulates actin cytoskeletal...

LIM-kinase 2 induces formation of stress fibres, focal adhesions and membrane blebs, dependent on its activation by Rho-associated kinase-catalysed phosphorylation at threonine-505.

Amano, T, Tanabe, K, Eto, T, Narumiya, S, Mizuno, K

LIM-kinase 1 and 2 (LIMK1 and LIMK2) phosphorylate cofilin and induce actin cytoskeletal reorganization. LIMK1 is activated by Rho-associated, coiled-coil-forming protein kinase (ROCK) and...

Counteracting regulation of chromatin remodeling at a fission yeast cAMP response element-related recombination hotspot by stress-activated protein kinase, cAMP-dependent kinase and meiosis regulators.

Mizuno, K, Hasemi, T, Ubukata, T, Yamada, T, Lehmann, E, Kohli, J, ...

In fission yeast, an ATF/CREB-family transcription factor Atf1-Pcr1 plays important roles in the activation of early meiotic processes via the stress-activated protein kinase (SAPK) and the...

Platelet-derived growth factor activates protein kinase C epsilon through redundant and independent signaling pathways involving phospholipase C gamma or phosphatidylinositol 3-kinase.

Moriya, S, Kazlauskas, A, Akimoto, K, Hirai, S, Mizuno, K, Takenawa, T, ...

Protein kinase C (PKC), a major cellular receptor for tumor-promoting phorbol esters and diacylglycerols (DGs), appears to be involved in a variety of cellular functions, although its activation...

Direct effect of basic fibroblast growth factor on gene transcription in a cell-free system.

Nakanishi, Y, Kihara, K, Mizuno, K, Masamune, Y, Yoshitake, Y, Nishikawa, K

Recent findings on the translocation of intact fibroblast growth factor (FGF) into the cell nucleus suggest that it functions directly in nuclear events. We examined the effect of human basic FGF...

Coordinated Regulation of the Genes Participating in Starch Biosynthesis by the Rice Floury-2 Locus.

Kawasaki, T., Mizuno, K., Shimada, H., Satoh, H., Kishimoto, N., Okumura, S., ...

The recessive floury-2 (flo-2) locus of rice (Oryza sativa L.), which is located on chromosome 4, causes a strong reduction in expression of the gene encoding an isoform of branching enzyme RBE1 in...

Identification, cDNA cloning, and gene expression of soluble starch synthase in rice (Oryza sativa L.) immature seeds.

Baba, T, Nishihara, M, Mizuno, K, Kawasaki, T, Shimada, H, Kobayashi, E, ...

Three forms of soluble starch synthase were resolved by anion-exchange chromatography of soluble extracts from immature rice (Oryza sativa L.) seeds, and each of these forms was further purified by...

Genetic control of the immune responsiveness to Streptococcus mutans by the major histocompatibility complex of the rat (RT1).

Niiyama, T, Kojima, H, Mizuno, K, Matsuno, Y, Fujii, H, Misonou, J, ...

The lymph node cells from 11 strains of rats, differing in the genotype of the major histocompatibility complex of the rat (RT1), were examined on the basis of their proliferative response to the...

Susceptibility of hepatitis B virus to disinfectants or heat.

Kobayashi, H, Tsuzuki, M, Koshimizu, K, Toyama, H, Yoshihara, N, Shikata, T, ...

Using direct chimpanzee inoculation as an assay method, we tested the abilities of the following chemical or physical treatments to inactivate hepatitis B virus in human plasma: 1% aqueous...

Presence of renin secretory granules in rat adrenal gland and stimulation of renin secretion by angiotensin II but not by adrenocorticotropin.

Mizuno, K, Hoffman, L H, McKenzie, J C, Inagami, T

Renin has been identified biochemically and immunohistochemically in the adrenal gland. We examined the subcellular distribution and behavior of adrenal renin. By differential centrifugation of...

A cDNA clone closely associated with non-A, non-B hepatitis.

Maéno, M, Kaminaka, K, Sugimoto, H, Esumi, M, Hayashi, N, Komatsu, K, ...

A lambda gt11 cDNA library was constructed from RNA purified from hepatitis B viral surface antigen-negative human plasma with high alanine aminotransferase activity. A cDNA clone, designated as...

MPTP delta, a putative murine homolog of HPTP delta, is expressed in specialized regions of the brain and in the B-cell lineage.

Mizuno, K, Hasegawa, K, Katagiri, T, Ogimoto, M, Ichikawa, T, Yakura, H

Protein tyrosine phosphatases (PTPs), together with protein tyrosine kinases (PTKs), are involved in the regulation of cell activation, growth, and differentiation. To further elucidate the fine...

A new member of the protein kinase C family, nPKC theta, predominantly expressed in skeletal muscle.

Osada, S, Mizuno, K, Saido, T C, Suzuki, K, Kuroki, T, Ohno, S

A new protein kinase C (PKC)-related cDNA with unique tissue distribution has been isolated and characterized. This cDNA encodes a protein, nPKC theta, which consists of 707 amino acid residues and...

Tumorigenicity of the met proto-oncogene and the gene for hepatocyte growth factor.

Rong, S, Bodescot, M, Blair, D, Dunn, J, Nakamura, T, Mizuno, K, ...

The met proto-oncogene is the tyrosine kinase growth factor receptor for hepatocyte growth factor/scatter factor (HGF/SF). It was previously shown that, like the oncogenic tpr-met, the mouse met...

Thyroid-specific enhancer-binding protein (T/EBP): cDNA cloning, functional characterization, and structural identity with thyroid transcription factor TTF-1.

Mizuno, K, Gonzalez, F J, Kimura, S

A cDNA clone encoding a thyroid-specific enhancer-binding protein (T/EBP) was isolated from a rat thyroid-derived FRTL-5 cell lambda gt 11 expression library, using a double-stranded oligonucleotide...

A small nuclear RNA, U5, can transform cells in vitro.

Hamada, K, Kumazaki, T, Mizuno, K, Yokoro, K

Low-molecular-weight RNA exhibiting transforming potential was identified in chemically induced lymphoma cells by the transformation of mink lung cells after transfection. The RNA was sequenced by...

Ras-dependent signal transduction is indispensable but not sufficient for the activation of AP1/Jun by PKC delta.

Hirai, S, Izumi, Y, Higa, K, Kaibuchi, K, Mizuno, K, Osada, S, ...

Modulation of gene expression by 12-O-tetradecanoylphorbol-13-acetate (TPA) is thought to be mediated by protein kinase C (PKC), a major cellular receptor for TPA. We confirm this by showing that the...

EGF or PDGF receptors activate atypical PKClambda through phosphatidylinositol 3-kinase.

Akimoto, K, Takahashi, R, Moriya, S, Nishioka, N, Takayanagi, J, Kimura, K, ...

Overexpression of a TPA-insensitive PKC member, an atypical protein kinase C (aPKClambda), results in an enhancement of the transcriptional activation of TPA response element (TRE) in cells...

Nuclear export of LIM-kinase 1, mediated by two leucine-rich nuclear-export signals within the PDZ domain.

Yang, N, Mizuno, K

LIM-kinase 1 (LIMK1) is a serine/threonine kinase that phosphorylates cofilin and regulates actin-filament dynamics. LIMK1, which contains two LIM domains and a single PDZ domain, localizes...

The N-terminal LIM domain negatively regulates the kinase activity of LIM-kinase 1.

Nagata, K, Ohashi, K, Yang, N, Mizuno, K

LIM-kinase 1 (LIMK1, where LIM is an acronym of the three gene products Lin-11, Isl-1 and Mec-3) is a serine/threonine kinase that phosphorylates cofilin and regulates actin cytoskeletal...

LIM-kinase 2 induces formation of stress fibres, focal adhesions and membrane blebs, dependent on its activation by Rho-associated kinase-catalysed phosphorylation at threonine-505.

Amano, T, Tanabe, K, Eto, T, Narumiya, S, Mizuno, K

LIM-kinase 1 and 2 (LIMK1 and LIMK2) phosphorylate cofilin and induce actin cytoskeletal reorganization. LIMK1 is activated by Rho-associated, coiled-coil-forming protein kinase (ROCK) and...

Counteracting regulation of chromatin remodeling at a fission yeast cAMP response element-related recombination hotspot by stress-activated protein kinase, cAMP-dependent kinase and meiosis regulators.

Mizuno, K, Hasemi, T, Ubukata, T, Yamada, T, Lehmann, E, Kohli, J, ...

In fission yeast, an ATF/CREB-family transcription factor Atf1-Pcr1 plays important roles in the activation of early meiotic processes via the stress-activated protein kinase (SAPK) and the...

Increased plasma cyclic nucleotide concentrations in congestive heart failure.

Ogawa, K, Shiozu, H, Mizuno, K, Ban, M, Ito, T, Satake, T

Plasma concentrations of cyclic nucleotides (adenosine monophosphate (AMP) and guanosine monophosphate (GMP) were measured by an ultrasensitive radioimmunoassay in 138 patients with heart failure due...

Pathological findings after percutaneous transluminal coronary angioplasty.

Mizuno, K, Kurita, A, Imazeki, N

Ten serial pathological cross sections at 1 mm intervals of both the left anterior descending artery at the site of a percutaneous transluminal coronary angioplasty and of the circumflex artery in...

Binocular indirect argon laser photocoagulator.

Mizuno, K

The binocular indirect argon laser photocoagulator was newly designed to enable visualisation of the entire fundus during panretinal laser photocoagulation and to treat retinal tears immediately...

Gyrate atrophy with hyperornithinaemia: different types of responsiveness to vitamin B6.

Hayasaka, S, Saito, T, Nakajima, H, Takaku, Y, Shiono, T, Mizuno, K, ...

Three cases of Japanese patients with gyrate atrophy of the choroid and retina with hyperornithinaemia were studied clinically and biochemically. The types of disease differed in responsiveness to...

Scanning electron microscopic study of Dacron degradation by ocular tissue extracts.

Hayasaka, S, Ishiguro, S, Shiono, T, Mizuno, K

A scanning electron microscopic study showed that the surface of Dacron thread became significantly roughened after treatment with bovine iris-ciliary body extracts. The Dacron-degrading factor in...

Clinical trials of vitamin B6 and proline supplementation for gyrate atrophy of the choroid and retina.

Hayasaka, S., Saito, T., Nakajima, H., Takahashi, O., Mizuno, K., Tada, K.

Five patients with gyrate atrophy of the choroid and retina were examined ophthalmologically, especially ophthalmoscopically, to evaluate trials of vitamin B6 (pyridoxine) or supplementary proline....

Gyrate atrophy of the choroid and retina: 15 Japanese patients.

Hayasaka, S, Shiono, T, Mizuno, K, Sasayama, C, Akiya, S, Tanaka, Y, ...

We examined 15 Japanese patients who had gyrate atrophy of the choroid and retina with hyperornithinaemia. Their visual acuities fell to 0.2 or worse in the second or third decade of life. Myopia...

A case of partial 5q trisomy associated with partial 7q monosomy.

Hara, S, Yamada, T, Nakai, H, Ohtani, A, Mizuno, K

A 1-year-old girl with partial 5q trisomy and partial 7q monosomy had ocular abnormalities that included bilateral blepharoptosis and Leber's congenital amaurosis. A single bright-flash...

Malignant melanoma of the choroid in a mother and retinoblastoma in her son.

Hayasaka, S, Mizuno, K

A 31-year-old woman was diagnosed as having a malignant melanoma of the choroid in the right eye. Twenty months later her 7-year-old son was diagnosed as having retinoblastoma in the right eye. Both...

Temporary corneal oedema after acute intake of alcohol.

Shiono, T, Asano, Y, Hashimoto, T, Mizuno, K

A 65-year-old man had diffuse, bilateral corneal oedema after acute intake of alcohol. Three days later the total opacification began to clear from the peripheral area towards the centre of the...

Oligoclonal expansion of circulating and tissue-infiltrating CD8+ T Cells with killer/effector phenotypes in juvenile dermatomyositis syndrome

MIZUNO, K, YACHIE, A, NAGAOKI, S, WADA, H, OKADA, K, KAWACHI, M, ...

Although triggering by infectious agents and abnormal immune responses may play some role in the pathogenesis of juvenile dermatomyositis syndrome (JDMS), the precise mechanism of muscle destruction...

Clinical investigation: increased serum stromal derived factor 1 alpha levels in pulmonary tuberculosis

Mizuno, K, Matsuyama, W, Mitsuyama, H, Watanabe, M, Higashimoto, I, Osame, M, ...

Pulmonary tuberculosis, a granulomatous disease, has few serological markers for its activity. Recently, an increased plasma level of stromal derived factor 1 alpha (SDF-1α), which can induce strong...

Selective expansion of CD16highCCR2− subpopulation of circulating monocytes with preferential production of haem oxygenase (HO)-1 in response to acute inflammation

Mizuno, K, Toma, T, Tsukiji, H, Okamoto, H, Yamazaki, H, Ohta, K, ...

Monocytes are composed of two distinct subpopulations in the peripheral blood as determined by their surface antigen expressions, profiles of cytokine production and functional roles played in vivo....

Heightened ability of monocytes from sarcoidosis patients to form multi-nucleated giant cells in vitro by supernatants of concanavalin A-stimulated mononuclear cells

Mizuno, K, Okamoto, H, Horio, T

The main immunocompetent cells in sarcoidal lesions are epithelioid cells and multi-nucleated giant cells (MGC), both of which are derived from monocyte-macrophage lineage cells. To understand...

Linkage-disequilibrium mapping narrows the Fukuyama-type congenital muscular dystrophy (FCMD) candidate region to

Toda, T., Miyake, M., Kobayashi, K., Mizuno, K., Saito, K., Osawa, M., ...

Fukuyama-type congenital muscular dystrophy (FCMD), the second most common form of muscular dystrophy in Japan, is an autosomal recessive severe muscular dystrophy associated with brain anomalies....

Mastoparan-induced phosphatidylcholine hydrolysis by phospholipase D activation in human astrocytoma cells.

Mizuno, K., Nakahata, N., Ohizumi, Y.

1. The effect of mastoparan on phosphatidylcholine hydrolysis was examined in 1321N1 human astrocytoma cells. Mastoparan (3-30 microM) caused an accumulation of diacylglycerol (DG) and phosphatidic...

Dual effects of mastoparan on intracellular free Ca2+ concentrations in human astrocytoma cells.

Nakahata, N., Ishimoto, H., Mizuno, K., Ohizumi, Y., Nakanishi, H.

1. The effect of mastoparan, a wasp venom toxin, on intracellular free Ca2+ concentration ([Ca2+]i) was examined in human astrocytoma cells. Mastoparan inhibited [Ca2+]i induced by carbachol (100...

Cooperative alpha-helix formation of beta-lactoglobulin and melittin induced by hexafluoroisopropanol.

Hirota, N., Mizuno, K., Goto, Y.

Alcohols denature the native state of proteins, and also stabilize the alpha-helical conformation in unfolded proteins and peptides. Among various alcohols, trifluoroethanol (TFE) and...