K. Murali-Krishna

Quantifying cell turnover using CFSE data (2005)

Ganusov, V.V., Pilyugin, S.S., Boer, R.J. De, Murali-Krishna, K., Ahmed, R., Antia, R.

The CFSE dye dilution assay is widely used to determine the number of divisions a given CFSE labelled cell has undergone in vitro and in vivo. In this paper, we consider how the data obtained with...

Recruitment Times, Proliferation, and Apoptosis Rates during the CD8+ T-Cell Response to Lymphocytic Choriomeningitis Virus (2001)

Boer, R.J. De, Oprea, M. (Mihaela), Antia, R. (Rustom), Murali-Krishna, K. (Kaja), Ahmed, R. (Rafi), Perelson, A.S. (Alan)

The specific CD8+ T-cell response during acute lymphocytic choriomeningitis virus (LCMV) infection of mice is characterized by a rapid proliferation phase, followed by a rapid death phase and...

Antiviral CD4 and CD8 T-cell memory: differences in the size of the response and activation requirements.

Whitmire, J K, Murali-Krishna, K, Altman, J, Ahmed, R

Following acute lymphocytic choriomeningitis virus (LCMV) infection, there is a potent antiviral CD8 T-cell response that eliminates the infection. This initial CD8 T-cell response is followed by a...