K. Muroya

Epidermal growth factor-receptor mutant lacking the autophosphorylation sites induces phosphorylation of Shc protein and Shc-Grb2/ASH association and retains mitogenic activity.

Gotoh, N, Tojo, A, Muroya, K, Hashimoto, Y, Hattori, S, Nakamura, S, ...

Epidermal growth factor (EGF) receptor (EGFR) can induce cell growth and transformation in a ligand-dependent manner. To examine whether the autophosphorylation of EGFR correlates with the capacity...

CRK protein binds to two guanine nucleotide-releasing proteins for the Ras family and modulates nerve growth factor-induced activation of Ras in PC12 cells.

Matsuda, M, Hashimoto, Y, Muroya, K, Hasegawa, H, Kurata, T, Tanaka, S, ...

It has been reported that growth factors activate Ras through a complex of an adaptor type SH2-containing molecule, Grb2, and a Ras guanine nucleotide-releasing protein (GNRP), mSos. We report on the...

Epidermal growth factor-receptor mutant lacking the autophosphorylation sites induces phosphorylation of Shc protein and Shc-Grb2/ASH association and retains mitogenic activity.

Gotoh, N, Tojo, A, Muroya, K, Hashimoto, Y, Hattori, S, Nakamura, S, ...

Epidermal growth factor (EGF) receptor (EGFR) can induce cell growth and transformation in a ligand-dependent manner. To examine whether the autophosphorylation of EGFR correlates with the capacity...

CRK protein binds to two guanine nucleotide-releasing proteins for the Ras family and modulates nerve growth factor-induced activation of Ras in PC12 cells.

Matsuda, M, Hashimoto, Y, Muroya, K, Hasegawa, H, Kurata, T, Tanaka, S, ...

It has been reported that growth factors activate Ras through a complex of an adaptor type SH2-containing molecule, Grb2, and a Ras guanine nucleotide-releasing protein (GNRP), mSos. We report on the...

Impaired male sex development in an infant with molecularly defined partial 9p monosomy: implication for a testis forming gene(s) on 9p.

Ogata, T, Muroya, K, Matsuo, N, Hata, J, Fukushima, Y, Suzuki, Y

This paper describes a genetically male infant with impaired male sex development and partial 9p monosomy. The external genitalia were ambiguous with microphallus (penile length at birth 10 mm, mean...

Deletion mapping and X inactivation analysis of a non-specific mental retardation gene at Xp21.3-Xp22.11

Muroya, K., Kinoshita, E., Kamimaki, T., Matsuo, N., Yorifugi, T., Ogata, T.

We report on deletion mapping and X inactivation analysis of a gene for X linked non-specific mental retardation (MRX) at Xp21.3-Xp22.11, on the basis of molecular studies in two families with Xp...

GATA3 abnormalities and the phenotypic spectrum of HDR syndrome

Muroya, K., Hasegawa, T., Ito, Y., Nagai, T., Isotani, H., Iwata, Y., ...

We report on GATA3 analysis and the phenotypic spectrum in nine Japanese families with the HDR syndrome (hypoparathyroidism, sensorineural deafness, and renal dysplasia) (MIM 146255). Fluorescence in...

Refined mapping of the gene for otopalatodigital syndrome type I

Kosho, T, Uemura, T, Tanimura, M, Ohashi, H, Muroya, K, Ogata, T