K. N. Westlund

The role of glutamate and GABA receptors in the generation of dorsal root reflexes by acute arthritis in the anaesthetized rat.

Rees, H, Sluka, K A, Westlund, K N, Willis, W D

1. In rats anaesthetized with pentobarbitone sodium, a unilateral acute arthritis was produced by the injection of kaolin and carrageenan into one knee-joint cavity. Four hours after injection, the...

The role of glutamate and GABA receptors in the generation of dorsal root reflexes by acute arthritis in the anaesthetized rat.

Rees, H, Sluka, K A, Westlund, K N, Willis, W D

1. In rats anaesthetized with pentobarbitone sodium, a unilateral acute arthritis was produced by the injection of kaolin and carrageenan into one knee-joint cavity. Four hours after injection, the...

Joint inflammation is reduced by dorsal rhizotomy and not by sympathectomy or spinal cord transection.

Sluka, K A, Lawand, N B, Westlund, K N

OBJECTIVES--To investigate the role of primary afferents, sympathetic postganglionic efferents and descending systems on the central control of peripheral inflammation. METHODS--Acute inflammation...

Excitatory amino acids, TNF-α, and chemokine levels in synovial fluids of patients with active arthropathies

MCNEARNEY, T, BAETHGE, B A, CAO, S, ALAM, R, LISSE, J R, WESTLUND, K N

The aim of this study was to assess the synovial fluid (SF) neurotransmitter excitatory amino acid (EAA) levels, including glutamate (Glu) and aspartate (Asp), in the context of SF levels of other...

Differential roles of neurokinin 1 and neurokinin 2 receptors in the development and maintenance of heat hyperalgesia induced by acute inflammation

Sluka, K A, Milton, M A, Willis, W D, Westlund, K N

Following induction of acute inflammation by intraarticular injection of kaolin and carrageenan into the knee joint in rats, there was a significant decrease in the withdrawal latency to radiant heat...