Isozaki, Y., Tada, R., Sun, Y., Nagashima, K., Zheng, H., Toyoda, S., ...
It is suggested that the uplift of Himalaya-Tibetan Plateau enhanced interior aridity in East Asia and resulted in development of middle latitude gobi and sandy deserts and accumulation of the eolian...
Isozaki, Y., Tada, R., Sun, Y., Nagashima, K., Zheng, H., Toyoda, S., ...
It is suggested that the uplift of Himalaya-Tibetan Plateau enhanced interior aridity in East Asia and resulted in development of middle latitude gobi and sandy deserts and accumulation of the eolian...
Okazaki, Y., Furuno, M., Kasukawa, T., Adachi, J., Bona, H., Kondo, S., ...
Only a small proportion of the mouse genome is transcribed into mature messenger RNA transcripts. There is an international collaborative effort to identify all full-length mRNA transcripts from the...
Okazaki, Y., Furuno, M., Kasukawa, T., Adachi, J., Bona, H., Kondo, S., ...
Only a small proportion of the mouse genome is transcribed into mature messenger RNA transcripts. There is an international collaborative effort to identify all full-length mRNA transcripts from the...
Okazaki, Y., Furuno, M., Kasukawa, T., Adachi, J., Bona, H., Kondo, S., ...
Only a small proportion of the mouse genome is transcribed into mature messenger RNA transcripts. There is an international collaborative effort to identify all full-length mRNA transcripts from the...
Takahashi, H, Matsuda, M, Kojima, A, Sata, T, Andoh, T, Kurata, T, ...
A number of studies have suggested that topoisomerase I (topo I) activity may be important in human immunodeficiency virus type 1 (HIV-1) replication. Specifically it has been reported that purified...
Tanaka, S, Morishita, T, Hashimoto, Y, Hattori, S, Nakamura, S, Shibuya, M, ...
CRK protein, together with GRB2/ASH and Nck proteins, belongs to the adaptor-type Src homology (SH)2-containing molecules, which transduce signals from tyrosine kinases. Here another guanine...
Origin of JC polyomavirus variants associated with progressive multifocal leukoencephalopathy.
Iida, T, Kitamura, T, Guo, J, Taguchi, F, Aso, Y, Nagashima, K, ...
JC polyomavirus (JCV) DNAs from the urine of nonimmunocompromised individuals (designated archetypal isolates) regularly contain a regulatory sequence that may have generated various regulatory...
Cloning of the cellulase gene from Ruminococcus albus and its expression in Escherichia coli.
Ohmiya, K, Nagashima, K, Kajino, T, Goto, E, Tsukada, A, Shimizu, S
The gene for cellulase from Ruminococcus albus F-40 was cloned in Escherichia coli HB101 with pBR322. A 3.4-kilobase-pair HindIII fragment encoding cellulase hybridized with the chromosomal DNA of R....
Hasegawa, H, Kiyokawa, E, Tanaka, S, Nagashima, K, Gotoh, N, Shibuya, M, ...
CRK belongs to a family of adaptor proteins that consist mostly of SH2 and SH3 domains. Far Western blotting with CRK SH3 has demonstrated that it binds to 135- to 145-, 160-, and 180-kDa proteins....
Rein, A, Mirro, J, Haynes, J G, Ernst, S M, Nagashima, K
In the murine leukemia viruses (MuLVs), the Env complex is initially cleaved by a cellular protease into gp70SU and pre15ETM. After the virus particle is released from the cell, the C-terminal 16...
Oberste, M S, Williamson, J C, Greenwood, J D, Nagashima, K, Copeland, T D, Gonda, M A
One of the six putative accessory genes of bovine immunodeficiency virus (BIV) is similar to those identified as rev in the human immunodeficiency virus and visna virus genomes. To further analyze...
Japanese encephalitis virus neurotropism is dependent on the degree of neuronal maturity.
Ogata, A, Nagashima, K, Hall, W W, Ichikawa, M, Kimura-Kuroda, J, Yasui, K
In a study on Fischer rats, all animals infected with Japanese encephalitis virus (JEV) before the age of 13 days died, but animals infected after the age of 14 days did not die, confirming the...
Gonda, M A, Kaminchick, J, Oliff, A, Menke, J, Nagashima, K, Scolnick, E M
The pathogenic Friend virus complex is of considerable interest in that, although members of this group are genetically related, they differ markedly in biochemical and biological properties....
Gonda, M A, Young, H A, Elser, J E, Rasheed, S, Talmadge, C B, Nagashima, K, ...
Rasheed rat sarcoma virus (RaSV) has been shown to code for a protein of 29,000 Mr not present in replication-competent rat type C helper virus (RaLV)-infected cells. This protein is a fused gene...
Nagashima, K, Yoshida, M, Seiki, M
Human T-cell leukemia virus type I (HTLV-I) contains the pX sequence which codes for the trans-activator of the long terminal repeat (LTR) and is thus postulated to be associated with leukemogenesis...
Multiple isolates and characteristics of human T-cell leukemia virus type II.
Hall, W W, Takahashi, H, Liu, C, Kaplan, M H, Scheewind, O, Ijichi, S, ...
Human T-cell leukemia (or lymphotropic) virus type II (HTLV-II) was isolated from eight HTLV-seropositive patients, six of whom were also infected with human immunodeficiency virus, by cocultivation...
Human immunodeficiency virus-like particles produced by a vaccinia virus expression vector.
Karacostas, V, Nagashima, K, Gonda, M A, Moss, B
Infectious retrovirus particles consist of a core structure containing RNA and gag-pol polypeptides surrounded by a lipid membrane studded with env proteins. A recombinant vaccinia virus was designed...
Neurovirulence of murine coronavirus JHM temperature-sensitive mutants in rats.
Wege, H, Koga, M, Watanabe, R, Nagashima, K, Ter Meulen, V
The murine coronavirus strain JHM is highly neurotropic in rats and has a marked tendency to cause demyelinating central nervous system diseases after intracerebral inoculation. The clinical diseases...
Tanaka, S, Hattori, S, Kurata, T, Nagashima, K, Fukui, Y, Nakamura, S, ...
Human CRK protein is a homolog of the chicken v-crk oncogene product and consists mostly of src homology region 2 (SH2) and SH3, which are shared by many proteins, in particular those involved in...
In situ hybridisation with digoxigenin-labelled DNA probes for detection of viral genomes.
Furuta, Y, Shinohara, T, Sano, K, Meguro, M, Nagashima, K
The applicability of a recently developed non-radioactive DNA labelling and detection method, which uses the digoxigenin (DIG) enzyme linked immunosorbent assay (ELISA) system, for the detection of...
Nagata, S, Nagashima, K, Tsunetsugu-Yokota, Y, Fujimura, K, Miyazaki, M, Kaziro, Y
Messenger RNA for yeast cytosolic polypeptide chain elongation factor 1 alpha (EF-1 alpha) was partially purified from Saccharomyces cerevisiae. Double-stranded complementary DNA (cDNA) was...
Béguin, P, Nagashima, K, Nishimura, M, Gonoi, T, Seino, S
ATP-sensitive potassium (K(ATP)) channels play important roles in many cellular functions such as hormone secretion and excitability of muscles and neurons. Classical ATP-sensitive potassium (K(ATP))...
Late viral interference induced by transdominant Gag of an endogenous retrovirus
Mura, M., Murcia, P., Caporale, M., Spencer, T.E., Nagashima, K., Rein, A., ...
The sheep genome harbors 20 copies of endogenous retroviruses (enJSRVs) closely related to the exogenous and oncogenic Jaagsiekte sheep retrovirus (JSRV). One of the enJSRV loci, enJS56A1, has a...
Takahashi, H, Matsuda, M, Kojima, A, Sata, T, Andoh, T, Kurata, T, ...
A number of studies have suggested that topoisomerase I (topo I) activity may be important in human immunodeficiency virus type 1 (HIV-1) replication. Specifically it has been reported that purified...
Tanaka, S, Morishita, T, Hashimoto, Y, Hattori, S, Nakamura, S, Shibuya, M, ...
CRK protein, together with GRB2/ASH and Nck proteins, belongs to the adaptor-type Src homology (SH)2-containing molecules, which transduce signals from tyrosine kinases. Here another guanine...
Origin of JC polyomavirus variants associated with progressive multifocal leukoencephalopathy.
Iida, T, Kitamura, T, Guo, J, Taguchi, F, Aso, Y, Nagashima, K, ...
JC polyomavirus (JCV) DNAs from the urine of nonimmunocompromised individuals (designated archetypal isolates) regularly contain a regulatory sequence that may have generated various regulatory...
Cloning of the cellulase gene from Ruminococcus albus and its expression in Escherichia coli.
Ohmiya, K, Nagashima, K, Kajino, T, Goto, E, Tsukada, A, Shimizu, S
The gene for cellulase from Ruminococcus albus F-40 was cloned in Escherichia coli HB101 with pBR322. A 3.4-kilobase-pair HindIII fragment encoding cellulase hybridized with the chromosomal DNA of R....
Hasegawa, H, Kiyokawa, E, Tanaka, S, Nagashima, K, Gotoh, N, Shibuya, M, ...
CRK belongs to a family of adaptor proteins that consist mostly of SH2 and SH3 domains. Far Western blotting with CRK SH3 has demonstrated that it binds to 135- to 145-, 160-, and 180-kDa proteins....
Rein, A, Mirro, J, Haynes, J G, Ernst, S M, Nagashima, K
In the murine leukemia viruses (MuLVs), the Env complex is initially cleaved by a cellular protease into gp70SU and pre15ETM. After the virus particle is released from the cell, the C-terminal 16...
Oberste, M S, Williamson, J C, Greenwood, J D, Nagashima, K, Copeland, T D, Gonda, M A
One of the six putative accessory genes of bovine immunodeficiency virus (BIV) is similar to those identified as rev in the human immunodeficiency virus and visna virus genomes. To further analyze...
Japanese encephalitis virus neurotropism is dependent on the degree of neuronal maturity.
Ogata, A, Nagashima, K, Hall, W W, Ichikawa, M, Kimura-Kuroda, J, Yasui, K
In a study on Fischer rats, all animals infected with Japanese encephalitis virus (JEV) before the age of 13 days died, but animals infected after the age of 14 days did not die, confirming the...
Gonda, M A, Kaminchick, J, Oliff, A, Menke, J, Nagashima, K, Scolnick, E M
The pathogenic Friend virus complex is of considerable interest in that, although members of this group are genetically related, they differ markedly in biochemical and biological properties....
Gonda, M A, Young, H A, Elser, J E, Rasheed, S, Talmadge, C B, Nagashima, K, ...
Rasheed rat sarcoma virus (RaSV) has been shown to code for a protein of 29,000 Mr not present in replication-competent rat type C helper virus (RaLV)-infected cells. This protein is a fused gene...
Nagashima, K, Yoshida, M, Seiki, M
Human T-cell leukemia virus type I (HTLV-I) contains the pX sequence which codes for the trans-activator of the long terminal repeat (LTR) and is thus postulated to be associated with leukemogenesis...
Multiple isolates and characteristics of human T-cell leukemia virus type II.
Hall, W W, Takahashi, H, Liu, C, Kaplan, M H, Scheewind, O, Ijichi, S, ...
Human T-cell leukemia (or lymphotropic) virus type II (HTLV-II) was isolated from eight HTLV-seropositive patients, six of whom were also infected with human immunodeficiency virus, by cocultivation...
Human immunodeficiency virus-like particles produced by a vaccinia virus expression vector.
Karacostas, V, Nagashima, K, Gonda, M A, Moss, B
Infectious retrovirus particles consist of a core structure containing RNA and gag-pol polypeptides surrounded by a lipid membrane studded with env proteins. A recombinant vaccinia virus was designed...
Neurovirulence of murine coronavirus JHM temperature-sensitive mutants in rats.
Wege, H, Koga, M, Watanabe, R, Nagashima, K, Ter Meulen, V
The murine coronavirus strain JHM is highly neurotropic in rats and has a marked tendency to cause demyelinating central nervous system diseases after intracerebral inoculation. The clinical diseases...
Tanaka, S, Hattori, S, Kurata, T, Nagashima, K, Fukui, Y, Nakamura, S, ...
Human CRK protein is a homolog of the chicken v-crk oncogene product and consists mostly of src homology region 2 (SH2) and SH3, which are shared by many proteins, in particular those involved in...
In situ hybridisation with digoxigenin-labelled DNA probes for detection of viral genomes.
Furuta, Y, Shinohara, T, Sano, K, Meguro, M, Nagashima, K
The applicability of a recently developed non-radioactive DNA labelling and detection method, which uses the digoxigenin (DIG) enzyme linked immunosorbent assay (ELISA) system, for the detection of...
Nagata, S, Nagashima, K, Tsunetsugu-Yokota, Y, Fujimura, K, Miyazaki, M, Kaziro, Y
Messenger RNA for yeast cytosolic polypeptide chain elongation factor 1 alpha (EF-1 alpha) was partially purified from Saccharomyces cerevisiae. Double-stranded complementary DNA (cDNA) was...
Béguin, P, Nagashima, K, Nishimura, M, Gonoi, T, Seino, S
ATP-sensitive potassium (K(ATP)) channels play important roles in many cellular functions such as hormone secretion and excitability of muscles and neurons. Classical ATP-sensitive potassium (K(ATP))...
Late viral interference induced by transdominant Gag of an endogenous retrovirus
Mura, M., Murcia, P., Caporale, M., Spencer, T.E., Nagashima, K., Rein, A., ...
The sheep genome harbors 20 copies of endogenous retroviruses (enJSRVs) closely related to the exogenous and oncogenic Jaagsiekte sheep retrovirus (JSRV). One of the enJSRV loci, enJS56A1, has a...
Induction of brain tumors by a newly isolated JC virus (Tokyo-1 strain).
Nagashima, K., Yasui, K., Kimura, J., Washizu, M., Yamaguchi, K., Mori, W.
A newly isolated virus from a patient with progressive multifocal leukoencephalopathy (PML) (Tokyo-1 strain) was found serologically identical to JC virus (Mad-1 strain) and showed high...
Multifocal angiomyolipoma affecting the liver and lung without tuberous sclerosis
Saito, M, Tsukamoto, T, Takahashi, T, Sai, K, Fujii, H, Nagashima, K
The occurrence of angiomyolipoma (AML) in tissue other than the kidney is uncommon, as is multiple AML developing exclusively in organs other than the kidney. This report describes a case in which...
Ogata, A, Matsuura, T, Tashiro, K, Moriwaka, F, Demura, T, Koyanagi, T, ...
Mannen, T, Iwata, M, Toyokura, Y, Nagashima, K
Histopathological description of a special nerve cell group of the sacral spinal cord in five cases of amyotrophic lateral sclerosis is presented. Remarkable preservation of this group of neurones...
MRI-pathological correlate of brain lesions in a necropsy case of HTLV-I associated myelopathy.
Ogata, A, Nagashima, K, Tashiro, K, Miyakawa, A, Mikuni, C
A postmortem case of HTLV-I associated myelopathy (HAM)/tropical spastic paraparesis (TSP) with a history of remission and exacerbation of neurological signs and symptoms, resembling those of...