Wang, Z.-G., Williams, L. J., Zhang, X.-F., Zatorski, A., Kudryashov, V., Ragupathi, G., ...
We have previously reported on a carbohydrate-based vaccine program for immunotherapy in cancer patients. One such vaccine, based on the globo H antigen conjugated to the protein keyhole limpet...
Slovin, S. F., Ragupathi, G., Adluri, S., Ungers, G., Terry, K., Kim, S., ...
The complex carbohydrate molecule globo H hexasaccharide has been synthesized, conjugated to keyhole limpet hemocyanin, and administered with the immunologic adjuvant QS-21 as a vaccine for patients...
Haraguchi, M, Yamashiro, S, Yamamoto, A, Furukawa, K, Takamiya, K, Lloyd, K O, ...
For the isolation of ganglioside GD3 synthase (EC 2.4.99.8) cDNA, we developed an expression cloning approach that used an anti-GD2 monoclonal antibody for selection. A host recipient cell line that...
Kitamura, K, Stockert, E, Garin-Chesa, P, Welt, S, Lloyd, K O, Armour, K L, ...
Le(y)-reactive monoclonal antibodies (mAbs) were generated in mice by immunization with synthetic Le(y) neoglycoproteins or with Le(y)-expressing cells. Serological analysis indicated that mAbs...
Human monoclonal antibody with dual GM2/GD2 specificity derived from an immunized melanoma patient.
Yamaguchi, H, Furukawa, K, Fortunato, S R, Livingston, P O, Lloyd, K O, Oettgen, H F, ...
GM2 ganglioside is a common cell surface constituent of human melanoma and other tumors of neuroectodermal origin, and vaccination with GM2 ganglioside results in high levels of anti-GM2 antibodies...
Real, F X, Furukawa, K S, Mattes, M J, Gusik, S A, Cordon-Cardo, C, Oettgen, H F, ...
Antibodies present in the serum of melanoma patient FD detect an antigenic determinant (FD) restricted to the autologous melanoma cell line SK-MEL-131. This cell-surface determinant is carried on a...
Schrump, D S, Furukawa, K, Yamaguchi, H, Lloyd, K O, Old, L J
Lymph node lymphocytes from patients with primary lung cancer were immortalized with Epstein-Barr virus, and culture supernatants were screened for cell-surface reactivity against allogeneic cancer...
Cell-surface antigens of melanoma recognized by human monoclonal antibodies.
Yamaguchi, H, Furukawa, K, Fortunato, S R, Livingston, P O, Lloyd, K O, Oettgen, H F, ...
Human monoclonal antibodies (mAbs) were derived from lymph node lymphocytes and peripheral blood lymphocytes (PBL) from patients with melanoma. Four methods for generating human mAbs were compared:...
Two-dimensional polyacrylamide gel electrophoresis has been used to compare the Nonidet P-40 soluble, [3H]glucosamine-labeled glycoproteins of human kidney cancer cell lines and short-term cultures...
Ueda, R, Ogata, S, Morrissey, D M, Finstad, C L, Szkudlarek, J, Whitmore, W F, ...
Seventeen monoclonal antibodies derived from fusions with spleen cells of mice immunized with established culture lines of renal cancers identified nine cell-surface antigenic systems. Six of the...
Cell surface antigens of human bladder cancer defined by mouse monoclonal antibodies.
Fradet, Y, Cordon-Cardo, C, Thomson, T, Daly, M E, Whitmore, W F, Lloyd, K O, ...
Mouse monoclonal antibodies were obtained by immunization with cultured human bladder cancer or lysates of bladder papilloma. They identify 11 distinct antigenic systems as defined by serological...
Mattes, M J, Cordon-Cardo, C, Lewis, J L, Old, L J, Lloyd, K O
Mouse monoclonal antibodies to several cell surface antigens of human ovarian and endometrial carcinomas have been produced. The distribution of the antigens was determined by mixed hemagglutination...
Cairncross, J G, Mattes, M J, Beresford, H R, Albino, A P, Houghton, A N, Lloyd, K O, ...
The surface antigens of cultured human malignant astrocytomas were analyzed by using mouse monoclonal antibodies. BALB/c mice were immunized repeatedly with either SK-MG-1 [a glial fibrillary acidic...
Dippold, W G, Lloyd, K O, Li, L T, Ikeda, H, Oettgen, H F, Old, L J
Eighteen mouse monoclonal antibodies were selected for reactivity with cell surface antigens of the immunizing human melanoma cell line SK-MEL-28. Six distinct antigenic systems were defined by...
AU cell-surface antigen of human malignant melanoma: solubilization and partial characterization.
Carey, T E, Lloyd, K O, Takahashi, T, Travassos, L R, Old, L J
AU antigen is defined by reactions of sera from patient AU with cell-surface antigens of cultured autologous melanoma cells (SK-MEL-28). Past studies established that no available cell type other...
Expression of Ia-like antigens on cultured human malignant melanoma cell lines.
Winchester, R J, Wang, C Y, Gibofsky, A, Kunkel, H G, Lloyd, K O, Old, L J
Human malignant melanoma cell lines were found to bear Ia-like cell surface determinants demonstrable by hetero- or alloantisera and by direct identification of the characteristic bimolecular...
Travassos, L. R., Gorin, P. A. J., Lloyd, K. O.
The proton and 13C magnetic resonance (CMR) spectra of 10 Sporothrix schenckii and three Ceratocystis stenoceras rhamnomannans were studied. On the basis of their CMR spectra, the rhamnomannans from...
Mendonça-Hagler, Leda C., Travassos, L. R., Lloyd, K. O., Phaff, H. J.
Deoxyribonucleic acid (DNA) base composition, as measured by guanine plus cytosine (G + C) content, was determined in 17 strains of Sporothrix schenckii and Ceratocystis species. The average G + C...
Travassos, L. R., Gorin, P. A. J., Lloyd, K. O.
Rhamnomannans from several isolates of Sporothrix schenckii and Ceratocystis species were compared. No major differences emerged in the analysis of the carbohydrate composition of polysaccharides...
Wang, Z.-G., Williams, L. J., Zhang, X.-F., Zatorski, A., Kudryashov, V., Ragupathi, G., ...
We have previously reported on a carbohydrate-based vaccine program for immunotherapy in cancer patients. One such vaccine, based on the globo H antigen conjugated to the protein keyhole limpet...
Slovin, S. F., Ragupathi, G., Adluri, S., Ungers, G., Terry, K., Kim, S., ...
The complex carbohydrate molecule globo H hexasaccharide has been synthesized, conjugated to keyhole limpet hemocyanin, and administered with the immunologic adjuvant QS-21 as a vaccine for patients...
Haraguchi, M, Yamashiro, S, Yamamoto, A, Furukawa, K, Takamiya, K, Lloyd, K O, ...
For the isolation of ganglioside GD3 synthase (EC 2.4.99.8) cDNA, we developed an expression cloning approach that used an anti-GD2 monoclonal antibody for selection. A host recipient cell line that...
Kitamura, K, Stockert, E, Garin-Chesa, P, Welt, S, Lloyd, K O, Armour, K L, ...
Le(y)-reactive monoclonal antibodies (mAbs) were generated in mice by immunization with synthetic Le(y) neoglycoproteins or with Le(y)-expressing cells. Serological analysis indicated that mAbs...
Human monoclonal antibody with dual GM2/GD2 specificity derived from an immunized melanoma patient.
Yamaguchi, H, Furukawa, K, Fortunato, S R, Livingston, P O, Lloyd, K O, Oettgen, H F, ...
GM2 ganglioside is a common cell surface constituent of human melanoma and other tumors of neuroectodermal origin, and vaccination with GM2 ganglioside results in high levels of anti-GM2 antibodies...
Real, F X, Furukawa, K S, Mattes, M J, Gusik, S A, Cordon-Cardo, C, Oettgen, H F, ...
Antibodies present in the serum of melanoma patient FD detect an antigenic determinant (FD) restricted to the autologous melanoma cell line SK-MEL-131. This cell-surface determinant is carried on a...
Schrump, D S, Furukawa, K, Yamaguchi, H, Lloyd, K O, Old, L J
Lymph node lymphocytes from patients with primary lung cancer were immortalized with Epstein-Barr virus, and culture supernatants were screened for cell-surface reactivity against allogeneic cancer...
Cell-surface antigens of melanoma recognized by human monoclonal antibodies.
Yamaguchi, H, Furukawa, K, Fortunato, S R, Livingston, P O, Lloyd, K O, Oettgen, H F, ...
Human monoclonal antibodies (mAbs) were derived from lymph node lymphocytes and peripheral blood lymphocytes (PBL) from patients with melanoma. Four methods for generating human mAbs were compared:...
Two-dimensional polyacrylamide gel electrophoresis has been used to compare the Nonidet P-40 soluble, [3H]glucosamine-labeled glycoproteins of human kidney cancer cell lines and short-term cultures...
Ueda, R, Ogata, S, Morrissey, D M, Finstad, C L, Szkudlarek, J, Whitmore, W F, ...
Seventeen monoclonal antibodies derived from fusions with spleen cells of mice immunized with established culture lines of renal cancers identified nine cell-surface antigenic systems. Six of the...
Cell surface antigens of human bladder cancer defined by mouse monoclonal antibodies.
Fradet, Y, Cordon-Cardo, C, Thomson, T, Daly, M E, Whitmore, W F, Lloyd, K O, ...
Mouse monoclonal antibodies were obtained by immunization with cultured human bladder cancer or lysates of bladder papilloma. They identify 11 distinct antigenic systems as defined by serological...
Mattes, M J, Cordon-Cardo, C, Lewis, J L, Old, L J, Lloyd, K O
Mouse monoclonal antibodies to several cell surface antigens of human ovarian and endometrial carcinomas have been produced. The distribution of the antigens was determined by mixed hemagglutination...
Cairncross, J G, Mattes, M J, Beresford, H R, Albino, A P, Houghton, A N, Lloyd, K O, ...
The surface antigens of cultured human malignant astrocytomas were analyzed by using mouse monoclonal antibodies. BALB/c mice were immunized repeatedly with either SK-MG-1 [a glial fibrillary acidic...
Dippold, W G, Lloyd, K O, Li, L T, Ikeda, H, Oettgen, H F, Old, L J
Eighteen mouse monoclonal antibodies were selected for reactivity with cell surface antigens of the immunizing human melanoma cell line SK-MEL-28. Six distinct antigenic systems were defined by...
AU cell-surface antigen of human malignant melanoma: solubilization and partial characterization.
Carey, T E, Lloyd, K O, Takahashi, T, Travassos, L R, Old, L J
AU antigen is defined by reactions of sera from patient AU with cell-surface antigens of cultured autologous melanoma cells (SK-MEL-28). Past studies established that no available cell type other...
Expression of Ia-like antigens on cultured human malignant melanoma cell lines.
Winchester, R J, Wang, C Y, Gibofsky, A, Kunkel, H G, Lloyd, K O, Old, L J
Human malignant melanoma cell lines were found to bear Ia-like cell surface determinants demonstrable by hetero- or alloantisera and by direct identification of the characteristic bimolecular...
Travassos, L. R., Gorin, P. A. J., Lloyd, K. O.
The proton and 13C magnetic resonance (CMR) spectra of 10 Sporothrix schenckii and three Ceratocystis stenoceras rhamnomannans were studied. On the basis of their CMR spectra, the rhamnomannans from...
Mendonça-Hagler, Leda C., Travassos, L. R., Lloyd, K. O., Phaff, H. J.
Deoxyribonucleic acid (DNA) base composition, as measured by guanine plus cytosine (G + C) content, was determined in 17 strains of Sporothrix schenckii and Ceratocystis species. The average G + C...
Travassos, L. R., Gorin, P. A. J., Lloyd, K. O.
Rhamnomannans from several isolates of Sporothrix schenckii and Ceratocystis species were compared. No major differences emerged in the analysis of the carbohydrate composition of polysaccharides...