K. Patel

Publication List Details

Period

1900 - 2009

Number

152

Co-Authors

Diversity in the student learning experience and time devoted to study: a comparative analysis of the UK and European evidence (2009)

Brennan, J, Patel, K, Tang, W

This report examines international differences in the student experiences including the hours students devote to study activity. The UK data analaysed here is partly drawn from the suvey carried out...

Table of Contents (2009)

Request Comments, K. Patel

This memo provides information for the Internet community. It does not specify an Internet standard of any kind. Distribution of this memo is unlimited. Copyright Notice Copyright (C) The Internet...

Table of Contents (2008)

Request Comments, K. Patel

This memo provides information for the Internet community. It does not specify an Internet standard of any kind. Distribution of this memo is unlimited. Copyright Notice Copyright (C) The Internet...

Xenon in Mercury-Manganese Stars (2008)

Dworetsky, M. M., Persaud, J. L., Patel, K.

Previous studies of elemental abundances in Mercury-Manganese (HgMn) stars have occasionally reported the presence of lines of the ionized rare noble gas Xe II, especially in a few of the hottest...

Student identitites in mass higher education (2008)

Brennan, J, Patel, K, Amoral, A, Bleiklie, I, Musselin, C

Based on interviews with students, which were carried out in the SOMUL project, this paper explores the nature of student identity in increasingly pluralist conditions, when higher education is more...

2 (2007)

I. B. Turksen, A. Esper, K. Patel, S. A. Starks, V. Kreinovich

In classical (two-valued) logic, CNF and DNF forms of each propositional formula are equivalent to each other. In fuzzy logic, CNF and DNF forms are not equivalent, they form an interval that...

Severe periodontitis is associated with systemic inflammation and a dysmetabolic status: a case–control study (2007)

Nibali, L., D'Aiuto, F., Griffiths, G., Patel, K., Suvan, J., Tonetti, M.S.

Background and Aim: A cluster of metabolic factors defines a syndrome that predisposes to diabetes and cardiovascular disease. Chronic infections such as periodontitis might alter these individual...

Daily versus weekly azithromycin in cystic fibrosis patients. (2007)

McCormack, J. G., Bell, S. C., Sharon S., Walmsley, K., Patel, K., Wainwright, C., ...

Four randomised, placebo-controlled trials have previously documented the clinical benefits of azithromycin (AZM) in cystic fibrosis (CF) patients. The present study examined whether the beneficial...

Daily versus weekly azithromycin in cystic fibrosis patients. (2007)

McCormack, J. G., Bell, S. C., Senini, S., Walmsley, K., Patel, K., Wainwright, C., ...

Four randomised, placebo-controlled trials have previously documented the clinical benefits of azithromycin (AZM) in cystic fibrosis (CF) patients. The present study examined whether the beneficial...

Fat oxidation before and after a high fat load in the obese insulin-resistant state (2006)

Blaak, E.E., Hul, G., Verdich, C., Stich, V., Martinez, A., Petersen, M., ...

Background: Obesity may be associated with a lowered use of fat as a fuel, which may contribute to the enlarged adipose tissue stores. Aim: The aim of the present study was to study fatty acid use in...

Constrained Route Distribution for Border Gateway Protocol/MultiProtocol Label Switching (BGP/MPLS) Internet Protocol (IP) Virtual Private Networks (VPNs) (2006)

L. Martini, R. Raszuk, K. Patel, J. Guichard

This document specifies an Internet standards track protocol for the Internet community, and requests discussion and suggestions for improvements. Please refer to the current edition of the...

Combining visualization and statistical analysis to improve operator confidence and efficiency for failure detection and localization (2005)

Bodik, P., Friedman, G., Biewald, L., Levine, H., Candea, G., Patel, K., ...

Web applications suffer from software and configuration faults that lower their availability. Recovering from failure is dominated by the time interval between when these faults appear and when they...

CRT12: MYOCARDIAL VIABILITY IS A BETTER THAN QRS DURATION IN PREDICTING CLINICAL BENFIT FROM CARDIAC RESYNCHRONISATION THERAPY (2005)

Chalil, S, Muhyaldeen, S, Khadjooi, K, Srivastava, S, Ellery, S, Yousef, ZR, ...

Background Although the benefits of cardiac resynchronisation therapy (CRT) are well established, they are difficult to predict from clinical, ECG or echocardiographic parameters. Gadolinium...

Diffusion MR imaging for cerebral abscess (2004)

Jati, A., Venkatesh, S.K., Patel, K., Malik, S.

We report a case of cerebral abscess, which ruptured into the lateral ventricle. The radiological features on conventional MRI, appearance on both diffusion weighted images (DWI) and apparent...

Diffusion MR imaging for cerebral abscess (2004)

Jati, A., Venkatesh, S.K., Patel, K., Malik, S.

We report a case of cerebral abscess, which ruptured into the lateral ventricle. The radiological features on conventional MRI, appearance on both diffusion weighted images (DWI) and apparent...

Diffusion MR imaging for cerebral abscess (2004)

Jati, A., Venkatesh, S.K., Patel, K., Malik, S.

We report a case of cerebral abscess, which ruptured into the lateral ventricle. The radiological features on conventional MRI, appearance on both diffusion weighted images (DWI) and apparent...

High Speed Simulator - A Simulator for All Seasons (2004)

Patel, K., Reinholtz, W., Robinson, W.

This paper will discuss the evolution of the Multimission Ground Systems Office's (MGSO) High Speed Spacecraft Simulator (HSS) development at the Jet Propulsion Laboratory. This paper will examine...

Highly Autonomous Systems Workshop (2004)

Doyle, R., Rasmussen, R., Man, G., Patel, K.

It is our aim by launching a series of workshops on the topic of highly autonomous systems to reach out to the larger community interested in technology development for remotely deployed systems,...

Reducing cache misses by application-specific re-configurable indexing (2004)

K. Patel, L. Benini, E. Macii, M. Poncino

The predictability of memory access patterns in embedded systems can be successfully exploited to devise effective application-specific cache optimizations. In this work, we propose an improved...

Weekly 5-fluorouracil and leucovorin: achieving lower toxicity with higher dose-intensity in adjuvant chemotherapy after colorectal cancer resection (2004)

Patel, K., Anthoney, D. A., Crellin, A. M., Sebag-Montefiore, D., Messruther, J., Seymour, M. T.

Background: Current standard therapy following resection of high-risk colon cancer is intravenous bolus 5-fluorouracil (5-FU) with leucovorin (LV), but there is no consensus on the optimum regimen of...

A randomised clinical trial to assess the effect of total enteral and total parenteral nutritional support on metabolic, inflammatory and oxidative markers in patients with predicted severe acute pancreatitis (APACHE II ≥6) (2003)

Gupta, R., Patel, K., Calder, P.C., Yaqoob, P., Primrose, J.N., Johnson, C.D.

Background: Total enteral nutrition (TEN) within 48 h of admission has recently been shown to be safe and efficacious as part of the management of severe acute pancreatitis. Our aim was to ascertain...

Preliminary Multi-Disciplinary Optimization in Turbomachinery Design (2003)

Panchenko, V., Moustapha, H., Mah, S., Patel, K., Dowhan, M. J.

The gas turbine engine is a complex aerodynamic machine with performance, structural and manufacturability challenges. This paper gives an overview of a multidisciplinary optimization approach...

Mobilizing grassroots' technological innovations and traditional knowledge, values and institutions: articulating social and ethical capital (2003)

A. K. Gupta, R. Sinha, D. Koradia, R. Patel, M. Parmar, P. Rohit, ...

The Honey Bee Network has helped provide a sort of loose platform to converge creative, but uncoordinated individuals across not only Indian states having varying cultural, linguistic and social...

Complex chimeras to map ligand binding sites of GPCRs (2003)

Gearing, K.L., Barnes, A., Barnett, J., Brown, A., Cousens, D., Dowell, S., ...

Family 1a GPCRs are thought to bind small molecule ligands in a pocket comprising sequences from non‐contiguous transmembrane helices. In this study, receptor–ligand binding determinants were...

CD40 and CD86 upregulation with divergent CMRF44 expression on blood dendritic cells in inflammatory bowel diseases (2001)

Vuckovic, S, Florin, THJ, Khalil, D, Zhang, MF, Patel, K, Hamilton, I, ...

OBJECTIVE: Dendritic cells (DC) are the only antigen-presenting cells that can activate naive T lymphocytes and initiate a primary immune response. They are also thought to have a role in immune...

CD40 and CD86 upregulation with divergent CMRF44 expression on blood dendritic cells in inflammatory bowel diseases (2001)

Vuckovic, S, Florin, THJ, Khalil, D, Zhang, MF, Patel, K, Hamilton, I, ...

OBJECTIVE: Dendritic cells (DC) are the only antigen-presenting cells that can activate naive T lymphocytes and initiate a primary immune response. They are also thought to have a role in immune...

Are Galaxies Optically Thin to Their Own Lyman Continuum Radiation? I. M33 (1995)

Patel, K., Wilson, C. D.

Halpha and UBV photometry of the inner kpc of M33 are used to study the distribution of OB stars and HII regions in the galaxy and to determine whether individual regions of the galaxy are in a state...

Are Galaxies Optically Thin to Their Own Lyman Continuum Radiation? II. NGC 6822 (1995)

Patel, K., Wilson, C. D.

Halpha and UBV photometry of NGC 6822 are used to study the distribution of OB stars and HII regions in the galaxy and to determine whether individual regions of the galaxy are in a state of...

Splicing of the VASE exon of neural cell adhesion molecule (NCAM) in human small-cell lung carcinoma (SCLC) (1992)

Helfrich, W, De Leij, L, Healey, K, ...

Expression of the neural cell adhesion molecule (NCAM) on small-cell lung carcinoma (SCLC) cell lines and tumour tissue has been investigated. Cell lines were found to express highly sialylated NCAM....

DSC AND X-RAY DIFFRACTION INVESTIGATIONS OF PHASE TRANSITIONS IN HxBABA AND NBABA (1979)

Usha Deniz, K., Paranjpe, A., Mirza, E., Parvathanathan, P., Patel, K.

The phase transitions and the heats of transformation (ΔH), of the hexyl (HxBABA) and nonyl (NBABA) members of the series of compounds, p-n-Alkoxybenzylidene-p-Aminobenzoic Acids, have been...

DSC AND X-RAY DIFFRACTION INVESTIGATIONS OF PHASE TRANSITIONS IN HxBABA AND NBABA (1979)

Usha Deniz, K., Paranjpe, A., Mirza, E., Parvathanathan, P., Patel, K.

The phase transitions and the heats of transformation (ΔH), of the hexyl (HxBABA) and nonyl (NBABA) members of the series of compounds, p-n-Alkoxybenzylidene-p-Aminobenzoic Acids, have been...

DSC AND X-RAY DIFFRACTION INVESTIGATIONS OF PHASE TRANSITIONS IN HxBABA AND NBABA (1979)

Usha Deniz, K., Paranjpe, A., Mirza, E., Parvathanathan, P., Patel, K.

The phase transitions and the heats of transformation (ΔH), of the hexyl (HxBABA) and nonyl (NBABA) members of the series of compounds, p-n-Alkoxybenzylidene-p-Aminobenzoic Acids, have been...

TUBOCURARINE AND THE NEONATE (1976)

BENNETT, E. J, IGNACIO, A, PATEL, K, GRUNDY, E. M, SALEM, M. R

Tubocurarine, given as a single bolus, may be used safely for neuromuscular blockade in the neonate. The recommended dose is 250 μg/kg at birth, increasing to 500 μg/kg at 28 days of age. This...

Mutation of p53 in primary biopsy material and cell lines from Hodgkin disease.

Gupta, R K, Patel, K, Bodmer, W F, Bodmer, J G

The p53 tumor-suppressor gene encodes a nuclear phosphoprotein that arrests cell cycle progress at G1. It may facilitate DNA damage repair and is frequently mutated in many human tumors. Hodgkin...

Multiple independent defective suppressor-mutator transposon insertions in Arabidopsis: a tool for functional genomics.

Tissier, A F, Marillonnet, S, Klimyuk, V, Patel, K, Torres, M A, Murphy, G, ...

A new system for insertional mutagenesis based on the maize Enhancer/Suppressor-mutator (En/Spm) element was introduced into Arabidopsis. A single T-DNA construct carried a nonautonomous defective...

Function search in a large transcription factor gene family in Arabidopsis: assessing the potential of reverse genetics to identify insertional mutations in R2R3 MYB genes.

Meissner, R C, Jin, H, Cominelli, E, Denekamp, M, Fuertes, A, Greco, R, ...

More than 92 genes encoding MYB transcription factors of the R2R3 class have been described in Arabidopsis. The functions of a few members of this large gene family have been described, indicating...

Comparison of five selective media for identifying fecal carriage of vancomycin-resistant enterococci.

Landman, D, Quale, J M, Oydna, E, Willey, B, Ditore, V, Zaman, M, ...

There is no uniformly accepted method for detecting colonization with vancomycin-resistant enterococci (VRE). The sensitivities of five culture methods were determined for patients known to harbor...

Rapid diagnosis of respiratory syncytial virus infections in immunocompromised adults.

Englund, J A, Piedra, P A, Jewell, A, Patel, K, Baxter, B B, Whimbey, E

Although rapid antigen detection methods for the documentation of respiratory syncytial virus (RSV) infections are widely used with pediatric patients, these tests have not been prospectively...

Activity of herpes simplex virus type 1 latency-associated transcript (LAT) promoter in neuron-derived cells: evidence for neuron specificity and for a large LAT transcript.

Zwaagstra, J C, Ghiasi, H, Slanina, S M, Nesburn, A B, Wheatley, S C, Lillycrop, K, ...

By using chloramphenicol acetyltransferase (CAT) assays in neuron-derived cell lines, we show here that promoter activity associated with the herpes simplex virus type 1 latency-associated transcript...

In vivo study of an antimicrobial surgical drape system.

Conn, J, Bornhoeft, J W, Almgren, C, Mucha, D P, Olderman, J, Patel, K, ...

We performed a double-blind clinical study to determine the efficacy of nonwoven laparotomy drapes in which 3-(trimethoxysilyl)propyldimethyloctadecyl ammonium chloride, an antimicrobial agent, was...

Variability in gas production by Escherichia coli in enrichment media and its relationship to pH.

Meadows, P S, Anderson, J G, Patel, K, Mullins, B W

Variability in gas production in multiple subcultures of Escherichia coli was assessed in two selective enrichment media and in lactose peptone water. Considerable variability occurred with all media...

A novel and rapid method for isolating sequences adjacent to rare cutting sites and their use in physical mapping.

Patel, K, Cox, R, Shipley, J, Kiely, F, Frazer, K, Cox, D R, ...

We describe a simple PCR based technique which can be used to isolate sequences adjacent to rare cutter sites and can subsequently be employed for the construction of long range physical maps. The...

Relationship of oxygen and glutathione in protection against carbon tetrachloride-induced hepatic microsomal lipid peroxidation and covalent binding in the rat. Rationale for the use of hyperbaric oxygen to treat carbon tetrachloride ingestion.

Burk, R F, Lane, J M, Patel, K

CCl4 exerts its toxicity through its metabolites, including the free radicals CCl3. and CCl(3)00.. Oxygen strongly inhibits the hepatic cytochrome P-450-mediated formation of CCl3. from CCl4 and...

Expression of neural cell adhesion molecule (NCAM) isoforms in neuroblastoma.

Phimister, E, Kiely, F, Kemshead, J T, Patel, K

A comparative study on the expression of the neural cell adhesion molecule (NCAM) in human neuroblastoma cell lines and tissues was undertaken. NCAMs are a family of closely related cell surface...

Reduced glutathione protection against rat liver microsomal injury by carbon tetrachloride. Dependence on O2.

Burk, R F, Patel, K, Lane, J M

Rat liver microsomal membranes contain a reduced-glutathione-dependent protein(s) that inhibits lipid peroxidation in the ascorbate/iron microsomal lipid peroxidation system. It appears to exert its...

CA 125 and survival in ovarian cancer: preliminary communication.

Parker, D, Patel, K, Alred, E J, Harnden-Mayor, P, Naylor, B

CA 125 is an epithelial membrane marker which can be detected in the serum of patients with ovarian cancer and which may reflect tumour burden. In a group of 42 patients, the level of this marker has...

An analysis of the relationship between hydration and protein-DNA interactions.

Woda, J, Schneider, B, Patel, K, Mistry, K, Berman, H M

Eleven protein-DNA crystal structures were analyzed to test the hypothesis that hydration sites predicted in the first hydration shell of DNA mark the positions where protein residues hydrogen-bond...

Hydration of the phosphate group in double-helical DNA.

Schneider, B, Patel, K, Berman, H M

Water distributions around phosphate groups in 59 B-, A-, and Z-DNA crystal structures were analyzed. It is shown that the waters are concentrated in six hydration sites per phosphate and that the...

Mutation of p53 in primary biopsy material and cell lines from Hodgkin disease.

Gupta, R K, Patel, K, Bodmer, W F, Bodmer, J G

The p53 tumor-suppressor gene encodes a nuclear phosphoprotein that arrests cell cycle progress at G1. It may facilitate DNA damage repair and is frequently mutated in many human tumors. Hodgkin...

Multiple independent defective suppressor-mutator transposon insertions in Arabidopsis: a tool for functional genomics.

Tissier, A F, Marillonnet, S, Klimyuk, V, Patel, K, Torres, M A, Murphy, G, ...

A new system for insertional mutagenesis based on the maize Enhancer/Suppressor-mutator (En/Spm) element was introduced into Arabidopsis. A single T-DNA construct carried a nonautonomous defective...

Function search in a large transcription factor gene family in Arabidopsis: assessing the potential of reverse genetics to identify insertional mutations in R2R3 MYB genes.

Meissner, R C, Jin, H, Cominelli, E, Denekamp, M, Fuertes, A, Greco, R, ...

More than 92 genes encoding MYB transcription factors of the R2R3 class have been described in Arabidopsis. The functions of a few members of this large gene family have been described, indicating...

Comparison of five selective media for identifying fecal carriage of vancomycin-resistant enterococci.

Landman, D, Quale, J M, Oydna, E, Willey, B, Ditore, V, Zaman, M, ...

There is no uniformly accepted method for detecting colonization with vancomycin-resistant enterococci (VRE). The sensitivities of five culture methods were determined for patients known to harbor...

Rapid diagnosis of respiratory syncytial virus infections in immunocompromised adults.

Englund, J A, Piedra, P A, Jewell, A, Patel, K, Baxter, B B, Whimbey, E

Although rapid antigen detection methods for the documentation of respiratory syncytial virus (RSV) infections are widely used with pediatric patients, these tests have not been prospectively...

Activity of herpes simplex virus type 1 latency-associated transcript (LAT) promoter in neuron-derived cells: evidence for neuron specificity and for a large LAT transcript.

Zwaagstra, J C, Ghiasi, H, Slanina, S M, Nesburn, A B, Wheatley, S C, Lillycrop, K, ...

By using chloramphenicol acetyltransferase (CAT) assays in neuron-derived cell lines, we show here that promoter activity associated with the herpes simplex virus type 1 latency-associated transcript...

In vivo study of an antimicrobial surgical drape system.

Conn, J, Bornhoeft, J W, Almgren, C, Mucha, D P, Olderman, J, Patel, K, ...

We performed a double-blind clinical study to determine the efficacy of nonwoven laparotomy drapes in which 3-(trimethoxysilyl)propyldimethyloctadecyl ammonium chloride, an antimicrobial agent, was...

Variability in gas production by Escherichia coli in enrichment media and its relationship to pH.

Meadows, P S, Anderson, J G, Patel, K, Mullins, B W

Variability in gas production in multiple subcultures of Escherichia coli was assessed in two selective enrichment media and in lactose peptone water. Considerable variability occurred with all media...

A novel and rapid method for isolating sequences adjacent to rare cutting sites and their use in physical mapping.

Patel, K, Cox, R, Shipley, J, Kiely, F, Frazer, K, Cox, D R, ...

We describe a simple PCR based technique which can be used to isolate sequences adjacent to rare cutter sites and can subsequently be employed for the construction of long range physical maps. The...

Relationship of oxygen and glutathione in protection against carbon tetrachloride-induced hepatic microsomal lipid peroxidation and covalent binding in the rat. Rationale for the use of hyperbaric oxygen to treat carbon tetrachloride ingestion.

Burk, R F, Lane, J M, Patel, K

CCl4 exerts its toxicity through its metabolites, including the free radicals CCl3. and CCl(3)00.. Oxygen strongly inhibits the hepatic cytochrome P-450-mediated formation of CCl3. from CCl4 and...

Expression of neural cell adhesion molecule (NCAM) isoforms in neuroblastoma.

Phimister, E, Kiely, F, Kemshead, J T, Patel, K

A comparative study on the expression of the neural cell adhesion molecule (NCAM) in human neuroblastoma cell lines and tissues was undertaken. NCAMs are a family of closely related cell surface...

Reduced glutathione protection against rat liver microsomal injury by carbon tetrachloride. Dependence on O2.

Burk, R F, Patel, K, Lane, J M

Rat liver microsomal membranes contain a reduced-glutathione-dependent protein(s) that inhibits lipid peroxidation in the ascorbate/iron microsomal lipid peroxidation system. It appears to exert its...

CA 125 and survival in ovarian cancer: preliminary communication.

Parker, D, Patel, K, Alred, E J, Harnden-Mayor, P, Naylor, B

CA 125 is an epithelial membrane marker which can be detected in the serum of patients with ovarian cancer and which may reflect tumour burden. In a group of 42 patients, the level of this marker has...

An analysis of the relationship between hydration and protein-DNA interactions.

Woda, J, Schneider, B, Patel, K, Mistry, K, Berman, H M

Eleven protein-DNA crystal structures were analyzed to test the hypothesis that hydration sites predicted in the first hydration shell of DNA mark the positions where protein residues hydrogen-bond...

Hydration of the phosphate group in double-helical DNA.

Schneider, B, Patel, K, Berman, H M

Water distributions around phosphate groups in 59 B-, A-, and Z-DNA crystal structures were analyzed. It is shown that the waters are concentrated in six hydration sites per phosphate and that the...

Infliximab in active early rheumatoid arthritis

Breedveld, F, Emery, P, Keystone, E, Patel, K, Furst, D, Kalden, J, ...

Objective: To examine the impact of the combination of infliximab plus methotrexate (MTX) on the progression of structural damage in patients with early rheumatoid arthritis (RA).

Influence of inflammatory bowel disease on the distribution and concentration of pancreatic secretory trypsin inhibitor within the colon.

Playford, R. J., Hanby, A. M., Patel, K., Calam, J.

Gastrointestinal epithelia contain a powerful protease inhibitor called pancreatic secretory trypsin inhibitor (PSTI). Patients with inflammatory bowel disease have changes in mucus structure...

CD40 and CD86 upregulation with divergent CMRF44 expression on blood dendritic cells in inflammatory bowel diseases

Vuckovic, S, Florin, THJ, Khalil, D, Zhang, MF, Patel, K, Hamilton, I, ...

OBJECTIVE: Dendritic cells (DC) are the only antigen-presenting cells that can activate naive T lymphocytes and initiate a primary immune response. They are also thought to have a role in immune...

Hyperplastic polyps: a cell lineage which both synthesizes and secretes trefoil-peptides and has phenotypic similarity with the ulcer-associated cell lineage.

Hanby, A. M., Poulsom, R., Singh, S., Jankowski, J., Hopwood, D., Elia, G., ...

Hyperplastic polyps are common benign lesions of uncertain histogenesis, which occur in the colon in populations at risk for colorectal carcinoma. They contain neutral/MUC1 gene-related mucin which...

Prediction of prognosis in patients with uveal melanoma using fluorescence in situ hybridisation

Patel, K., Edmondson, N., Talbot, F., Parsons, M, Rennie, I., Sisley, K.

BACKGROUND/AIMS—Uveal melanoma is the commonest malignancy of the eye, with a high proportion of patients dying of metastatic disease. Tumours showing a loss of chromosome 3 and gains of...

An ultrasound based classification of periocular haemangiomas

Bowman, R J C, Nischal, K K, Patel, K, Harper, J I

Aims: To propose a classification system for periocular haemangiomas based on ultrasound evaluation.

Carbon monoxide diffusing capacity in polycythaemia rubra vera.

Greening, A P, Patel, K, Goolden, A W, Munro, A J, Hughes, J M

The diffusing capacity of the lung, or transfer factor, for carbon monoxide (TLCO) was measured in 12 patients with polycythaemia rubra vera. This was significantly raised (mean 152% predicted, SEM...

Interpretation of increases in the transfer coefficient for carbon monoxide (TLCO/VA or KCO).

Lipscomb, D J, Patel, K, Hughes, J M

During a 15-month period, 27 patients were seen in a routine clinical pulmonary function laboratory in whom the transfer coefficient (TLCO/VA or KCO), measured by the single breath technique, was...

Certainty and mortality prediction in critically ill children

Marcin, J, Pretzlaff, R, Pollack, M, Patel, K, Ruttimann, U

Objectives: The objective of this study is to investigate the relationship between a physician's subjective mortality prediction and the level of confidence with which that mortality prediction is...

Dental knowledge of accident and emergency senior house officers

Patel, K, Driscoll, P

Objectives: To determine the dental knowledge of accident and emergency (A&E) senior house officers (SHOs).

Ambulatory pulmonary artery pressure monitoring during sleep and exercise in normal individuals and patients with COPD

Raeside, D, Brown, A, Patel, K, Welsh, D, Peacock, A

Background: Pulmonary hypertension is a common complication of chronic obstructive airways disease (COPD) and its presence implies a poor prognosis. However, it is difficult to measure and its...

Dopa responsive dystonia.

Patel, K, Roskrow, T, Davis, J S, Heckmatt, J Z

There may be insufficient awareness of dopa responsive dystonia (DRD), which has a characteristic diurnal variation of symptoms. Two children are reported in whom the diagnosis of DRD was missed. The...

Convergence between CD98 and integrin‐mediated T‐lymphocyte co‐stimulation

Warren, A P, Patel, K, Miyamoto, Y, Wygant, J N, Woodside, D G, McIntyre, B W

CD98 is a widely expressed cell surface heterodimeric glycoprotein, which is rapidly up‐regulated upon activation of T lymphocytes. Monoclonal antibody (mAb) 80A10 recognizes an epitope on CD98 and...

Development of a Regional Model of Care for Ambulatory Total Shoulder Arthroplasty: A Pilot Study

Gallay, S. H., Lobo, J. J. A., Baker, J., Smith, K., Patel, K.

Total shoulder arthroplasty (TSA) has traditionally been performed as inpatient surgery to provide adequate postoperative analgesia via intermittent opioid administration. We developed a regional...

Diagnosis of Ewing's sarcoma and peripheral neuroectodermal tumour based on the detection of t(11;22) using fluorescence in situ hybridisation.

Taylor, C., Patel, K., Jones, T., Kiely, F., De Stavola, B. L., Sheer, D.

Fluorescence in situ hybridisation (FISH) has been used increasingly for gene mapping and ordering probes on interphase and metaphase preparations. The association of consistent chromosomal...

The effects of chemotherapy on morphology, cellular proliferation, apoptosis and oncoprotein expression in primary breast carcinoma.

Rasbridge, S. A., Gillett, C. E., Seymour, A. M., Patel, K., Richards, M. A., Rubens, R. D., ...

The use of chemotherapy as a form of primary treatment for breast cancer is increasing and, as a result, more resection specimens contain tumours which have been exposed to cytotoxic drugs. We have...

Annexin VI has tumour-suppressor activity in human A431 squamous epithelial carcinoma cells.

Theobald, J., Hanby, A., Patel, K., Moss, S. E.

In this study we show that heterologous expression of annexin VI in A431 squamous carcinoma cells caused a marked suppression of tumour cell growth when cells were cultured subcutaneously in nude...

An inbred colony of oncogene transgenic mice: diversity of tumours and potential as a therapeutic model.

Thomas, H., Hanby, A. M., Smith, R. A., Hagger, P., Patel, K., Raikundalia, B., ...

Transgenic mice carrying the activated rat c-neu oncogene under transcriptional control of the MMTV promoter were backcrossed to BALB/c mice, with the aim of developing a model for cancer therapy. A...

Monoclonal antibody 3F8 recognises the neural cell adhesion molecule (NCAM) in addition to the ganglioside GD2.

Patel, K., Rossell, R. J., Pemberton, L. F., Cheung, N. K., Walsh, F. S., Moore, S. E., ...

The monoclonal antibody 3F8 has been described as binding to the ganglioside GD2. This antibody, of the IgG3 isotype, has been used in immunotherapy, radioimmunolocalisation and targeted radiation...

Neuroblastoma in the very young child: biological considerations.

Kemshead, J. T., Patel, K., Phimister, B.

Neuroblastoma is one of the childhood malignancies that frustrates both the clinical and scientist. Clearly, some forms of the disease are relatively benign and the patient can expect to be cured....

The expression of small cell lung cancer related antigens in foetal lung and kidney.

Bobrow, L. G., Happerfield, L., Patel, K.

The presence and distribution of antigens recognised by the antibodies submitted to the Second International Workshop on Small Cell Lung Cancer Antigens has been mapped on human foetal lung and...

Expression of the cluster 1 antigen (neural cell adhesion molecule) in neuroectodermal tumours.

Patel, K., Frost, G., Kiely, F., Phimister, E., Coakham, H. B., Kemshead, J. T.

In this study, we have investigated the expression of the neural cell adhesion molecule (NCAM) in the human brain, primary brain tumours and neuroblastoma. Adult brain was found to express discrete...