Campbell, K S, Ogris, E, Burke, B, Su, W, Auger, K R, Druker, B J, ...
Polyomavirus middle tumor antigen (MT) transforms a large number of cell types by binding to and modulating the activities of cellular proteins. Previous genetic analysis defined in MT an independent...
Campbell, K S, Auger, K R, Hemmings, B A, Roberts, T M, Pallas, D C
Two subunits of protein phosphatase 2A (PP2A) have been shown previously to bind to the small t and middle T antigens (ST and MT, respectively) of polyomavirus. To determine sequences important for...
Serunian, L A, Auger, K R, Roberts, T M, Cantley, L C
Phosphatidylinositol 3-kinase associates with the polyomavirus middle T antigen (PyMTAg)-pp60c-src complex in polyomavirus-transformed cells. Here we show that anti-PyMTAg immunoprecipitates from...
Inducible interleukin-1 gene expression in human vascular smooth muscle cells.
Libby, P, Ordovas, J M, Birinyi, L K, Auger, K R, Dinarello, C A
Interleukin-1 (IL-1) mediates many components of generalized host response to injury and may also contribute to local vascular pathology during immune or inflammatory responses. Because altered...
A tightly associated serine/threonine protein kinase regulates phosphoinositide 3-kinase activity.
Carpenter, C L, Auger, K R, Duckworth, B C, Hou, W M, Schaffhausen, B, Cantley, L C
We identified a serine/threonine protein kinase that is associated with and phosphorylates phosphoinositide 3-kinase (PtdIns 3-kinase). The serine kinase phosphorylates both the 85- and 110-kDa...
Campbell, K S, Ogris, E, Burke, B, Su, W, Auger, K R, Druker, B J, ...
Polyomavirus middle tumor antigen (MT) transforms a large number of cell types by binding to and modulating the activities of cellular proteins. Previous genetic analysis defined in MT an independent...
Campbell, K S, Auger, K R, Hemmings, B A, Roberts, T M, Pallas, D C
Two subunits of protein phosphatase 2A (PP2A) have been shown previously to bind to the small t and middle T antigens (ST and MT, respectively) of polyomavirus. To determine sequences important for...
Serunian, L A, Auger, K R, Roberts, T M, Cantley, L C
Phosphatidylinositol 3-kinase associates with the polyomavirus middle T antigen (PyMTAg)-pp60c-src complex in polyomavirus-transformed cells. Here we show that anti-PyMTAg immunoprecipitates from...
A tightly associated serine/threonine protein kinase regulates phosphoinositide 3-kinase activity.
Carpenter, C L, Auger, K R, Duckworth, B C, Hou, W M, Schaffhausen, B, Cantley, L C
We identified a serine/threonine protein kinase that is associated with and phosphorylates phosphoinositide 3-kinase (PtdIns 3-kinase). The serine kinase phosphorylates both the 85- and 110-kDa...
Inducible interleukin-1 gene expression in human vascular smooth muscle cells.
Libby, P, Ordovas, J M, Birinyi, L K, Auger, K R, Dinarello, C A
Interleukin-1 (IL-1) mediates many components of generalized host response to injury and may also contribute to local vascular pathology during immune or inflammatory responses. Because altered...
Libby, P., Ordovas, J. M., Auger, K. R., Robbins, A. H., Birinyi, L. K., Dinarello, C. A.
Interleukin 1 (IL-1) can induce potentially pathogenic functions of vascular endothelial cells. This mediator was formerly thought to be produced primarily by activated macrophages. We report here...