Evaluation of the safety and immunogenicity of synthetic Aß42 (AN1792) in patients with AD (2005)
Bayer, A.J., Bullock, R., Jones, R.W., Wilkinson, D., Paterson, K.R., Jenkins, L., ...
Background: Aß42-immunization reduces plaque burden and improves cognition in transgenic mouse models of Alzheimer disease (AD). This phase 1 study evaluated the safety, tolerability, and...
Mortality study of 18 000 patients treated with omeprazole. (2002)
Bateman, D.N., Colin-Jones, D., Hartz, S., Langman, M., Logan, R.F., Mant, J, ...
Background: The long term safety of potent gastric acid suppressive therapy has yet to be established. Method: General practice record review at a median interval of 26 months followed by retrieval...
Changes in phagocytic function with glycaemic control in diabetic patients.
MacRury, S M, Gemmell, C G, Paterson, K R, MacCuish, A C
Phagocytic function was assessed by serial whole blood chemiluminescence in poorly controlled type 2 (non-insulin dependent) diabetic patients during efforts to improve glycaemic control and compared...
Changes in phagocytic function with glycaemic control in diabetic patients.
MacRury, S M, Gemmell, C G, Paterson, K R, MacCuish, A C
Phagocytic function was assessed by serial whole blood chemiluminescence in poorly controlled type 2 (non-insulin dependent) diabetic patients during efforts to improve glycaemic control and compared...
Postmarketing surveillance of the safety of cimetidine: 10 year mortality report.
Colin-Jones, D G, Langman, M J, Lawson, D H, Logan, R F, Paterson, K R, Vessey, M P
A total of 9928 cimetidine users were identified from prescriptions in four centres and followed for 10 years. The 'all-cause' mortality ratio fell from 1.9 in year 1 to 1.0 in years 8 to 10. Most of...
Mortality study of 18 000 patients treated with omeprazole
Bateman, D N, Colin-Jones, D, Hartz, S, Langman, M, Logan, R F, Mant, J, ...
Background: The long term safety of potent gastric acid suppressive therapy has yet to be established.
Effect of oral verapamil on glibenclamide stimulated insulin secretion.
Semple, C G, Omile, C, Buchanan, K D, Beastall, G H, Paterson, K R
In order to study the effect of the calcium antagonist, verapamil, on glibenclamide stimulated insulin release, nine healthy fasted male volunteers were given 5 mg oral glibenclamide with either 120...
Experience of temporary cardiac pacing in a district general hospital.
Temporary cardiac pacing is widely used in the management of dysrhythmias; increasingly it is being employed in district general hospitals without specialist cardiology facilities. A retrospective...
Record linkage study of hypokalaemia in hospitalized patients.
Paice, B. J., Paterson, K. R., Onyanga-Omara, F., Donnelly, T., Gray, J. M., Lawson, D. H.
Retrospective analysis of biochemical data from 58,167 hospital inpatients revealed that 21% developed hypokalaemia during hospitalization-in 5.2% the serum potassium was less than 3.0 mmol/l....
Watson, I. D., McBride, D., Paterson, K. R.
A case of fatal xylenol ingestion by a long-stay mental hospital patient is described. The clinical course was similar to that observed in other phenolic poisonings with active bowel sounds, nausea...