K. Saikrishnan

Unusual sugar specificity of banana lectin from Musa paradisiaca andits probable evolutionary origin. Crystallographic and modelling studies (2005)

Singh, DD, Saikrishnan, K, Kumar, Prashant, Surolia, A, Sekar, K, Vijayan, M

The crystal structure of a complex of methyl-\alpha-D-mannoside with banana lectin from Musa paradisiaca reveals two primary binding sites in the lectin, unlike in other lectins with beta-prism I...

Structure of Mycobacterium smegmatis single-stranded DNA-binding protein and a comparative study involving homologus SSBs: biological implications of structural plasticity and variability in quaternary association (2005)

Saikrishnan, K, Manjunath, GP, Singh, Pawan, Jeyakanthan, J, Dauter, Z, Sekar, K, ...

The structure of Mycobacterium smegmatis single-stranded DNA-binding protein (SSB) has been determined using three data sets collected from related crystals. The structure is similar to that of its...

X-ray structural studies of Mycobacterium tuberculosis RRF and a comparative study of RRFs of known structure. Molecular plasticity and biological implications (2005)

Saikrishnan, K, Kalapala, SK, Varshney, U, Vijayan, M

The crystal structure of Mycobacterium tuberculosis ribosome recycling factor has been determined and refined against three X-ray diffraction data sets, two collected at room temperature and the...

Structure of Mycobacterium smegmatis single-stranded DNA-binding protein and a comparative study involving homologus SSBs: biological implications of structural plasticity and variability in quaternary association (2005)

Saikrishnan, K, Manjunath, GP, Singh, Pawan, Jeyakanthan, J, Dauter, Z, Sekar, K, ...

The structure of Mycobacterium smegmatis single-stranded DNA-binding protein (SSB) has been determined using three data sets collected from related crystals. The structure is similar to that of its...

Unusual sugar specificity of banana lectin from Musa paradisiaca andits probable evolutionary origin. Crystallographic and modelling studies (2005)

Singh, DD, Saikrishnan, K, Kumar, Prashant, Surolia, A, Sekar, K, Vijayan, M

The crystal structure of a complex of methyl-\alpha-D-mannoside with banana lectin from Musa paradisiaca reveals two primary binding sites in the lectin, unlike in other lectins with beta-prism I...

X-ray structural studies of Mycobacterium tuberculosis RRF and a comparative study of RRFs of known structure. Molecular plasticity and biological implications (2005)

Saikrishnan, K, Kalapala, SK, Varshney, U, Vijayan, M

The crystal structure of Mycobacterium tuberculosis ribosome recycling factor has been determined and refined against three X-ray diffraction data sets, two collected at room temperature and the...

Purification, crystallization and preliminary X-ray structure analysis of the banana lectin from Musa paradisiaca (2004)

Singh, DD, Saikrishnan, K, Kumar, Prashant, Dauter, Z, Sekar, K, Surolia, A, ...

The banana lectin from Musa paradisiaca, MW 29.4 kDa, has been isolated, purified and crystallized. The trigonal crystals contain one dimeric molecule in the asymmetric unit. The structure has been...

Purification, crystallization and preliminary X-ray studies of Mycobacterium tuberculosis RRF (2004)

Saikrishnan, K, Kalapala, SK, Sagar, Bidya M, Rao, AR, Varshney, U, Vijayan, M

With the re-emergence of tuberculosis providing the impetus, research on Mycobacterium tuberculosis at the molecular level has registered considerable progress in recent years (Ratledge & Dale,...

Purification, crystallization and preliminary X-ray structure analysis of the banana lectin from Musa paradisiaca (2004)

Singh, DD, Saikrishnan, K, Kumar, Prashant, Dauter, Z, Sekar, K, Surolia, A, ...

The banana lectin from Musa paradisiaca, MW 29.4 kDa, has been isolated, purified and crystallized. The trigonal crystals contain one dimeric molecule in the asymmetric unit. The structure has been...

Purification, crystallization and preliminary X-ray studies of Mycobacterium tuberculosis RRF (2004)

Saikrishnan, K, Kalapala, SK, Sagar, Bidya M, Rao, AR, Varshney, U, Vijayan, M

With the re-emergence of tuberculosis providing the impetus, research on Mycobacterium tuberculosis at the molecular level has registered considerable progress in recent years (Ratledge & Dale,...

Structure of Mycobacterium tuberculosis Singlestranded DNA-binding Protein. Variability in Quaternary Structure and Its Implications (2003)

Saikrishnan, K, Jeyakanthan, J, Venkatesh, J, Acharya, N, Sekar, K, Varshney, U, ...

Single-stranded DNA-binding protein (SSB) is an essential protein necessary for the functioning of the DNA replication, repair and recombination machineries. Here we report the structure of the...

Structure of Mycobacterium tuberculosis Singlestranded DNA-binding Protein. Variability in Quaternary Structure and Its Implications (2003)

Saikrishnan, K, Jeyakanthan, J, Venkatesh, J, Acharya, N, Sekar, K, Varshney, U, ...

Single-stranded DNA-binding protein (SSB) is an essential protein necessary for the functioning of the DNA replication, repair and recombination machineries. Here we report the structure of the...

Substitutions at tyrosine 66 of Escherichia coli uracil DNA glycosylase lead to characterization of an efficient enzyme that is recalcitrant to product inhibition (2003)

Acharya, Narottam, Talawar, Ramappa K, Saikrishnan, K, Vijayan, M, Varshney, Umesh

Uracil DNA glycosylase (UDG), a ubiquitous and highly specific enzyme, commences the uracil excision repair pathway. Structural studies have shown that the tyrosine in a highly conserved GQDPY...

Substitutions at tyrosine 66 of Escherichia coli uracil DNA glycosylase lead to characterization of an efficient enzyme that is recalcitrant to product inhibition (2003)

Acharya, Narottam, Talawar, Ramappa K, Saikrishnan, K, Vijayan, M, Varshney, Umesh

Uracil DNA glycosylase (UDG), a ubiquitous and highly specific enzyme, commences the uracil excision repair pathway. Structural studies have shown that the tyrosine in a highly conserved GQDPY...

Domain closure and action of uracil DNA glycosylase (UDG): structures of new crystal forms containing the Escherichia coli enzyme and a comparative study of the known structures involving UDG (2002)

Saikrishnan, K, Sagar, Bidya M, Ravishankar, R, Roy, S, Purnapatre, K, Handa, P, ...

The structures of a new crystal form of free Escherichia coli uracil DNA glycosylase (UDG), containing four molecules in the asymmetric unit, and two forms of its complex with the proteinaceous...

Crystallization and preliminary X-ray studies of the single-stranded DNA-binding protein from Mycobacterium tuberculosis (2002)

Saikrishnan, K, Jeyakanthan, J, Venkatesh, J, Acharya, N, Purnapatre, K, Sekar, K, ...

Single-stranded DNA-binding proteins play an important role in DNA replication, repair and recombination. The protein from Mycobacterium tuberculosis (MtSSB) is a tetramer with 164 aminoacid residues...

Domain closure and action of uracil DNA glycosylase (UDG): structures of new crystal forms containing the Escherichia coli enzyme and a comparative study of the known structures involving UDG (2002)

Saikrishnan, K, Sagar, Bidya M, Ravishankar, R, Roy, S, Purnapatre, K, Handa, P, ...

The structures of a new crystal form of free Escherichia coli uracil DNA glycosylase (UDG), containing four molecules in the asymmetric unit, and two forms of its complex with the proteinaceous...

Crystallization and preliminary X-ray studies of the single-stranded DNA-binding protein from Mycobacterium tuberculosis (2002)

Saikrishnan, K, Jeyakanthan, J, Venkatesh, J, Acharya, N, Purnapatre, K, Sekar, K, ...

Single-stranded DNA-binding proteins play an important role in DNA replication, repair and recombination. The protein from Mycobacterium tuberculosis (MtSSB) is a tetramer with 164 aminoacid residues...

Substitutions at tyrosine 66 of Escherichia coli uracil DNA glycosylase lead to characterization of an efficient enzyme that is recalcitrant to product inhibition

Acharya, Narottam, Talawar, Ramappa K., Saikrishnan, K., Vijayan, M., Varshney, Umesh

Uracil DNA glycosylase (UDG), a ubiquitous and highly specific enzyme, commences the uracil excision repair pathway. Structural studies have shown that the tyrosine in a highly conserved GQDPY...

Substitutions at tyrosine 66 of Escherichia coli uracil DNA glycosylase lead to characterization of an efficient enzyme that is recalcitrant to product inhibition

Acharya, Narottam, Talawar, Ramappa K., Saikrishnan, K., Vijayan, M., Varshney, Umesh

Uracil DNA glycosylase (UDG), a ubiquitous and highly specific enzyme, commences the uracil excision repair pathway. Structural studies have shown that the tyrosine in a highly conserved GQDPY...