Gardiner,D. S., Gorman,M. R., Rytting,T. H., Sakai,K.
Acoustic emission (AE) sensors were used to monitor subscale graphite/epoxy pressure vessels that were subjected to increasing levels of impact damage. Impact damage was inflicted after each vessel...
Sakai, K, Gatanaga, H, Oka, S, Takiguchi, M
No abstract available.
Cosmic Ray Tests of the Prototype TPC for the ILC Experiment (2009)
Ackermann, K., Arai, S., Arogancia, D. C., Bacala, A. M., Ball, M., Behnke, T., ...
A time projection chamber (TPC) is a strong candidate for the central tracker of the international linear collider (ILC) experiment and we have been conducting a series of cosmic ray experiments...
Kano, A., Ferdelman, T.G., Williams, T., Henriet, J-P., Ishikawa, T., Kawagoe, N., ...
Sr isotope stratigraphy provides a new age model for the first complete section drilled through a deep-water coral mound. The 155-m-long section from Challenger Mound in the Porcupine Sea-bight,...
A GEM TPC End-Panel Pre-Prototype (2007)
Ishikawa, A., Aoza, A., Higashi, T., Sugiyama, A., Tsuji, H., Kato, Y., ...
A GEM TPC end panel pre-prototype was constructed for a large LC-TPC prototype to test its basic design philosophy and some of its engineering details. Its interim test results are presented.
Oouchi, H., Yamada, K., Sakai, K., Kizu, O., Kubota, T., Ito, H., ...
Optical trapping of metal particles in doughnut-shaped beam emitted by photonic-crystal laser (2007)
Akiyama, M., Sakai, K., Arita, K., Nomura, Y., Ito, K., Kodama, K., ...
Mutations in the GJB2 gene encoding connexin26 are the major cause of autosomal-recessive or -dominant nonsyndromic congenital sensorineural hearing loss (SNHL) (Kelsell et al., 1997; Kenneson et...
A novel ABCA12 mutation 3270delT causes harlequin ichthyosis (2006)
Akiyama, M., Sakai, K., Wolff, G., Hausser, I., McMillan, J.R., Sawamura, D., ...
On-site underground background measurements for the KASKA reactor-neutrino experiment (2006)
Furuta, H., Sakuma, K., Aoki, M., Fukuda, Y., Funaki, Y., Hara, T., ...
On-site underground background measurements were performed for the planned reactor-neutrino oscillation experiment KASKA at Kashiwazaki-Kariwa nuclear power station in Niigata, Japan. A...
Aoki, M., Akiyama, K., Fukuda, Y., Fukui, A., Funaki, Y., Furuta, H., ...
One of the current most-demanded experiments in neutrino physics is to measure the last mixing angle theta_13. KASKA is an experiment to detect new type of reactor neutrino oscillation and to measure...
Hayami, H, Yamaguchi, O, Mizutani, K, Sakai, K, Miyaji, A
No abstract available.
Reading hidden intentions in the human brain (2006)
Haynes, J-D., Sakai, K., Rees, G., Gilbert, S., Frith, C., Passingham, R.E.
When humans are engaged in goal-related processing, activity in prefrontal cortex is increased [1, 2]. However, it has remained unclear whether this prefrontal activity encodes a subject’s current...
Algebraic Curve for the SO(6) sector of AdS/CFT (2006)
Beisert,Niklas, Kazakov,V. A., Sakai,K.
We construct the general algebraic curve of degree four solving the classical sigma model on RxS5. Up to two loops it coincides with the algebraic curve for the dual sector of scalar operators in N=4...
Algebraic Curve for the SO(6) sector of AdS/CFT (2006)
Beisert, Niklas, Kazakov, V. A., Sakai, K.
We construct the general algebraic curve of degree four solving the classical sigma model on RxS5. Up to two loops it coincides with the algebraic curve for the dual sector of scalar operators in N=4...
Photonics: Lasers producing tailored beams (2006)
Miyai, E, Sakai, K, Okano, T, Kunishi, W, Ohnishi, D, Noda, S
Sakai, K, Smith, Emelyn G., Webber, Grant B., Baker, Murray, Wanless, Erica J., Butun, Vural, ...
The pH-responsive behavior of cationic diblock poly(2-(dimethylamino)ethyl methacrylate)-block-poly(2-(diethylamino)ethyl methacrylate) copolymer micelles adsorbed at the silica/aqueous solution...
A Novel ABCA12 Mutation 3270delT Causes Harlequin Ichthyosis (2006)
Akiyama, M., Sakai, K., Wolff, G., Hausser, J. R., McMillan, J. R., Sawamura, D., ...
The article presents a case of a baby girl who had been suffering from harlequin ichthyosis, a severe fatal congenital ichthyosis. Its clinical features include thick, plate-like scales with...
Sakai, K, Smith, Emelyn G., Webber, Grant B., Baker, Murray, Wanless, Erica J., Butun, Vural, ...
The pH-responsive behavior of cationic diblock poly(2-(dimethylamino)ethyl methacrylate)-block-poly(2-(diethylamino)ethyl methacrylate) copolymer micelles adsorbed at the silica/aqueous solution...
The Parent of Misfit-Layered Cobalt Oxides: [Sr2O2]qCoO2 (2005)
Yamauchi, H., Sakai, K., Nagai, T., Matsui, Y., Karppinen, M.
Misfit-layered (ML) cobalt oxides of the general formula of [MmA2Om+2]qCoO2 have been proven to be efficient thermoelectric materials as the structure is capable in accommodating the two seemingly...
Complete Spectrum of Long Operators in N=4 SYM at One Loop (2005)
Beisert, N., Kazakov, V. A., Sakai, K., Zarembo, K.
We construct the complete spectral curve for an arbitrary local operator, including fermions and covariant derivatives, of one-loop N=4 gauge theory in the thermodynamic limit. This curve perfectly...
The Algebraic Curve of Classical Superstrings on AdS_5xS^5 (2005)
Beisert, N., Kazakov, V. A., Sakai, K., Zarembo, K.
We investigate the monodromy of the Lax connection for classical IIB superstrings on AdS_5xS^5. For any solution of the equations of motion we derive a spectral curve of degree 4+4. The curve...
Using proton-transfer laser dyes for organic laser diodes (2005)
Sakai, K, Tsuzuki, T, Itoh, Y, Ichikawa, M, Taniguchi, Y
Copyright (2005) American Institute of Physics. This article may be downloaded for personal use only. Any other use requires prior permission of the author and the American Institute of Physics. The...
Some experimental studies on time-of-flight radiography using a pulsed neutron source (2005)
Kiyanagi, Y., Sakamoto, N., Iwasa, H., Kamiyama, T., Hiraga, F., Sato, S., ...
We are developing a fiber type two-dimentional (2-D) position-sensitive detector having a spatial resolution less than 0.5 mm in order to use it in the time-of-flight (TOF) measurements. The detector...
Some experimental studies on time-of-flight radiography using a pulsed neutron source (2005)
Kiyanagi, Y., Sakamoto, N., Iwasa, H., Kamiyama, T., Hiraga, F., Sato, S., ...
We are developing a fiber type two-dimentional (2-D) position-sensitive detector having a spatial resolution less than 0.5 mm in order to use it in the time-of-flight (TOF) measurements. The detector...
Some experimental studies on time-of-flight radiography using a pulsed neutron source (2005)
Kiyanagi, Y., Sakamoto, N., Iwasa, H., Kamiyama, T., Hiraga, F., Sato, S., ...
We are developing a fiber type two-dimentional (2-D) position-sensitive detector having a spatial resolution less than 0.5 mm in order to use it in the time-of-flight (TOF) measurements. The detector...
Exact Analysis of ESR Shift in the Spin-1/2 Heisenberg Antiferromagnetic Chain (2005)
Maeda, Y., Sakai, K., Oshikawa, M.
A systematic perturbation theory is developed for the ESR shift and is applied to the spin-1/2 Heisenberg chain. Using the Bethe ansatz technique, we exactly analyze the resonance shift in the first...
Lasing band-edge identification for a surface-emitting photonic crystal laser (2005)
Sakai, K, Miyai, E, Sakaguchi, T, Ohnishi, D, Okano, T, Noda, S
The map-based sequence of the rice genome (2005)
MATSUMOTO, T, WU, JZ, KANAMORI, H, KATAYOSE, Y, FUJISAWA, M, NAMIKI, N, ...
ABE, O, ABE, R, ENOMOTO, K, KIKUCHI, K, KOYAMA, H, MASUDA, H, ...
ABE, O, ABE, R, ENOMOTO, K, KIKUCHI, K, KOYAMA, H, MASUDA, H, ...
Posttranslational modifications of decidual IGFBP-1 by steroid hormones in vitro (2005)
Kabir-Salmani, M., Shimizu, Y., Sakai, K., Iwashita, M.
Insulin-like growth factor binding protein-1 (IGFBP-1) appears to regulate insulin-like growth factors (IGFs; IGF-I and IGF-II) biological activity within the local environment of human placenta by...
Posttranslational modifications of decidual IGFBP-1 by steroid hormones in vitro (2005)
Kabir-Salmani, M., Shimizu, Y., Sakai, K., Iwashita, M.
Insulin-like growth factor binding protein-1 (IGFBP-1) appears to regulate insulin-like growth factors (IGFs; IGF-I and IGF–II) biological activity within the local environment of human placenta by...
Algebraic Curve for the SO(6) sector of AdS/CFT (2004)
Beisert, N., Kazakov, V. A., Sakai, K.
We construct the general algebraic curve of degree four solving the classical sigma model on RxS5. Up to two loops it coincides with the algebraic curve for the dual sector of scalar operators in N=4...
Formation of very short pulse by neutron spin flip chopper for J-PARC (2004)
Ebisawa, T, Soyama, K, Yamazaki, D, Tasaki, S, Sakai, K, Oku, T, ...
An abnormal ultra-cold-neutron absorption in solid UCN-detectors (2004)
Kitagaki, T, Sakai, K, Hino, M, Utsuro, M, Higuchi, M, Geltenbort, P, ...
Kabir-Salmani, M., Shiokawa, S., Akimoto, Y., Sakai, K., Iwashita, M.
The role of integrins in the processes of adhesion and migration makes them attractive potential participants in the complex events of embryo implantation and placentation. Recently, the role of the...
Sakai,T., Li,S. H., Docheva,D., Grashoff,C., Sakai,K., Kostka,G., ...
Integrin-mediated cell-matrix interactions are essential for development, tissue homeostasis, and repair. Upon ligand binding, integrins are recruited into focal adhesions (FAs). Integrin-linked...
Sakai, T., Li, S. H., Docheva, D., Grashoff, C., Sakai, K., Kostka, G., ...
Integrin-mediated cell-matrix interactions are essential for development, tissue homeostasis, and repair. Upon ligand binding, integrins are recruited into focal adhesions (FAs). Integrin-linked...
Neutron spin flip chopper with very high S/N ratio for pulsed source (2003)
Tasaki, S, Ebisawa, T, Kawakami, S, Maruyama, R, Sakai, K, Oku, T, ...
Mineshige, A, Okada, S, Sakai, K, Kobune, M, Fujii, S, Matsumoto, H, ...
A resonance neutron-spin flipper for neutron spin echo at pulsed sources (2003)
Maruyama, R, Ebisawa, T, Tasaki, S, Hino, M, Takeda, M, Kawai, T, ...
Development of a spin flipper for an application of a neutron magnetic device (2003)
Oku, T, Sakai, K, Adachi, T, Ikeda, K, Shimizu, HM, Maruyama, R, ...
Neutron-beam control using a magnetic doublet (2002)
Oku, T, Adachi, T, Sakai, K, Shimizu, HM, Sasaki, K, Iwasa, H, ...
Haseyama, T., Asahi, K., Bowman, J. D., Delheij, P. P. J., Funahashi, H., Ishimoto, S., ...
The parity nonconserving spin rotation of neutrons in the 0.734-eV p-wave resonance of $^{139}La$ was measured with the neutron transmission method. Two optically polarized $^3He$ cells were used...
Problems in point-contact tunneling study on BSCCO (2000)
Murakami, H., Ogami, T., Qi, Y., Sakai, K., Ito, T., Shigaki, I., ...
Electrodynamic c-axis properties of YBa2Cu3O7-δ thin films in the THz frequency regime. (1999)
Ludwig, C., Sekinger, T., Kuhl, J., Tani, M., Sakai, K., ...
A synopsis of the family Callianassidae is presented. Defenitions are given of the subfamilies and genera. Keys to the sufamilies, genera, as well as seperate keys to the species occurring in certain...
Improvement and Restoration of Biomedical Images Blurred by Body Movement (1998)
Hori, J., Saitoh, Y., Kiryu, T., Okamoto, K., Sakai, K.
The restoration of biomedical images that have been blurred due to body movement are discussed. The observation system for these images is described using a mathematical operator and coordinate...
High-Pressure Phase Diagram of an Aluminium-Rich Al-Li Alloy at a Pressure of 5.4 GPa. (1998)
Matsumuro, A., Sakai, K., Senoo, M.
The high-pressure phase diagram of an aluminum-rich Al-Li alloy at a 5.4 GPa pressure was investigated; to determine the equilibrium state under high-pressure and high-temperature conditions, the...
Goto, T., Sakai, K., Kawanaka, A.
This paper concerned mmc in some important way and contained information about, utilized, or discussed these subjects: basic topics:, composite materials, data, experimental, reinforcement data...
Functional role of focal adhesion kinase in the process of implantation (1998)
Shiokawa, S, Yoshimura, Y, Nagamatsu, S, Sawa, H, Hanashi, H, Sakai, K, ...
Batchelor, M. T., Fridkin, V., Kuniba, A., Sakai, K.
We obtain the free energies and critical exponents of models associated with elliptic solutions of the star-triangle relation and reflection equation. The models considered are related to the affine...
Continuum-wise expansive diffeomorphisms (1997)
In this paper, we show that the $C^1$ interior of the set of all continuum-wise expansive diffeomorphisms of a closed manifold coincides with the $C^1$ interior of the set of all expansive...
Ovarian ablation in early breast cancer: Overview of the randomised trials. (1996)
CLARKE, M, COLLINS, R, DAVIES, C, GODWIN, J, GRAY, R, PETO, R, ...
Paganini, E. P., Sandy, D., Moreno, L., Kozlowski, L., Sakai, K.
Background Haemodynamic stability in intensive care unit (ICU) patient with acute renal failure (ARF) during intermittent dialytic support has been the focus for several variations to dialysis...
Birch, J.R., Simonis, G.J., Afsar, M.N., Clarke, R.N., Dutta, J.M., Frost, H.M., ...
IEEE Transactions on Microwave Theory and Techniques, 42(1994) S.956-65
Cografts of Adrenal Medulla With Pretransected Peripheral Nerve (1992)
I. Date, K. Sakai, Y. Hoshimoto, T. Furuta, S. Asari, T. Ohmoto
Upogebia trispinosa spec. nov. is described from Tokushima, Japan. The species is rather closely related to U. narutensis.
Proc.of the 1st Internat.Conf.on Supercomputing in Nuclear Applications,
Takesawa, S., Ohmi, S., Konno, Y., Sekiguchi, M., Shitaokoshi, S., Takahashi, T., ...
This study elucidates changes in membrane structure and permeability due to the methods of sterilisation and the conditions under which they are carried out. Tubular dialysis membranes of regenerated...
PRESENT STATUS OF UVSOR (1986)
Watanabe, M, Kasuga, T, Yonehara, H, Uchida, A, Sakai, K, Matsudo, O, ...
In *Tsukuba 1984, Proceedings, Accelerator Science and Technology*, 15-17
Okada, S., Sakai, K., Nakamura, N.
Factors that affect RBE values have been investigated in cultured cells. It was shown that: (1) Different RBE values were obtained with the same tritiated water treated cells depending upon the...
Two RFLPs identified by a human chromosome #2 clone at 2p15-2p16 (HGM8 assignment no. D2S5) (1985)
Shiloh, Y., Kanda, N., Kunkel, L.M., Bruns, G., Sakai, K., Latt, S.A.
Unidentified specimens of the genus Upogebia in the collection of the Rijksmuseum van Natuurlijke Historie in Leiden were studied. A ♀ from Angola proved to be closely related to U. subspinosa; it...
STRUCTURAL MODEL OF FLUORINATED AMORPHOUS-SILICON (a-Si : F) (1981)
Matsumura, H., Sakai, K., Kawakyu, Y., Furukawa, S.
A structural model for fluorinated amorphous-silicon containing no hydrogen (a-Si : F) is presented based on the experimental results of transmission electron microscopic measurement, infrared...
STRUCTURAL MODEL OF FLUORINATED AMORPHOUS-SILICON (a-Si : F) (1981)
Matsumura, H., Sakai, K., Kawakyu, Y., Furukawa, S.
A structural model for fluorinated amorphous-silicon containing no hydrogen (a-Si : F) is presented based on the experimental results of transmission electron microscopic measurement, infrared...
STRUCTURAL MODEL OF FLUORINATED AMORPHOUS-SILICON (a-Si : F) (1981)
Matsumura, H., Sakai, K., Kawakyu, Y., Furukawa, S.
A structural model for fluorinated amorphous-silicon containing no hydrogen (a-Si : F) is presented based on the experimental results of transmission electron microscopic measurement, infrared...
Activity of primate inferotemporal neurons related to a sought target in pair-association task.
Naya, Y, Sakai, K, Miyashita, Y
Visual long-term memory in primates has been assessed by using the pair-association (PA) task, in which a subject retrieves and chooses the paired associate of a cue picture. Our previous studies on...
Roychoudhury, S, Sakai, K, Chakrabarty, A M
The exopolysaccharide alginate is a major virulence factor in the pathogenicity of Pseudomonas aeruginosa infecting the lungs of cystic fibrosis (CF) patients. Alginate synthesis by P. aeruginosa is...
Takada, S, Nakamura, M, Matsueda, T, Kondo, R, Sakai, K
A method for the degradation of dioxins by white rot fungi was developed. Degradation of a mixture of 10 kinds of tetra- to octachlorodibenzo-p-dioxins (polychlorinated dibenzo-p-dioxins [PCDDs]) and...
Sakai, K, Oshima, K, Moriguchi, M
N-Acyl-D-glutamate amidohydrolase from Pseudomonas sp. strain 5f-1 was inducibly produced by D isomers of N-acetylglutamate, glutamate, aspartate, and asparagine. The enzyme has been purified to...
Schwartz, L B, Sakai, K, Bradford, T R, Ren, S, Zweiman, B, Worobec, A S, ...
Tryptase, a protease produced by all mast cells, was evaluated as a clinical marker of systemic mastocytosis. Two sandwich immunoassays were evaluated, one which used the mAb G5 for capture, the...
Sakai, K, Narihara, M, Kasama, Y, Wakayama, M, Moriguchi, M
Thermostable exochitinase was purified to homogeneity from the culture fluid of Bacillus stearothermophilus CH-4, which was isolated from agricultural compost containing shrimp and crabs. The enzyme...
Sakai, K, Ma, X Y, Gordienko, I, Volsky, D J
Two molecularly cloned coisolates of human immunodeficiency virus type 1 (HIV-1) have been found to exhibit different phenotypes of viral expression, either rapid and cytopathic (N1T-A virus) or...
Sakai, K, Dewhurst, S, Ma, X Y, Volsky, D J
A cytopathic human immunodeficiency virus type 1 (HIV-1) isolate containing multiple virus genotypes was molecularly cloned, and the biological activity of six randomly selected clones was assessed...
Adachi, A, Sakai, K, Kitamura, N, Nakanishi, S, Niwa, O, Matsuyama, M, ...
The highly oncogenic erythroleukemia-inducing Friend mink cell focus-inducing (MCF) virus was molecularly cloned in phage lambda gtWES.lambda B, and the DNA sequences of the env gene and the long...
Dewhurst, S, Sakai, K, Bresser, J, Stevenson, M, Evinger-Hodges, M J, Volsky, D J
The nature of the interaction between human immunodeficiency virus (HIV) and human cells of astrocytic origin was studied in vitro with cultured glial cells and intact HIV or infectious molecular...
Sakai, K, Narita, H, Adachi, A, Tsuruta, S, Yorifuji, T, Ishimoto, A
By a biological assay system using phenotypically mixed ecotropic and xenotropic murine leukemia viruses, we investigated whether in the virions of a xenotropic virus there is N- or B-tropic Fv-1...
Sakai, K, Sinha, A A, Mitchell, D J, Zamvil, S S, Rothbard, J B, McDevitt, H O, ...
The peptide p89-101 (Val-His-Phe-Phe-Lys-Asn-Ile-Val-Thr-Pro-Arg-Thr-Pro) of myelin basic protein is encephalitogenic in mice expressing H-2q and H-2s antigens. Six of 13 encephalitogen-specific...
Sakai, K, Zamvil, S S, Mitchell, D J, Hodgkinson, S, Rothbard, J B, Steinman, L
Two synthetic immunodominant and nonencephalitogenic peptides of myelin basic protein, N1-20 and AcN9-20, effectively compete with an encephalitogenic peptide, AcN1-11, in an in vitro T-cell response...
Yamamura, Y, Hattori, T, Obaru, K, Sakai, K, Asou, N, Takatsuki, K, ...
The gene coding for the protein LD78 was isolated from stimulated human tonsillar lymphocytes by differential hybridization. The gene product consisted of 92 amino acids with characteristics of...
Two RFLPs identified by a human chromosome #2 clone at 2p15-2p16 (HGM8 assignment no. D2S5).
Shiloh, Y, Kanda, N, Kunkel, L M, Bruns, G, Sakai, K, Latt, S A
Sakai, K, Sakaguchi, J, Yamamoto, M
We have developed a high-frequency cotransformation system which is useful in introducing nonreplicating circular DNA plasmids into the fission yeast Schizosaccharomyces pombe. This system depends on...
Biological and Chemical Detection of Trichothecene Mycotoxins of Fusarium Species
Ueno, Y., Sato, N., Ishii, K., Sakai, K., Tsunoda, H., Enomoto, M.
The procedure for biological and chemical detection of trichothecene-type mycotoxins and its application to the screening of Fusarium for toxic strains were described.
Shiloh, Y, Shipley, J, Brodeur, G M, Bruns, G, Korf, B, Donlon, T, ...
DNA amplification, manifested by homogeneously staining regions in chromosomes and by extrachromosomal, double minute bodies, is characteristic of many neuroblastoma cell lines. Sequences recruited...
A novel case of a sporadic desmoid tumour with mutation of the beta catenin gene.
Shitoh, K, Konishi, F, Iijima, T, Ohdaira, T, Sakai, K, Kanazawa, K, ...
A 42 year old man without familial adenomatous polyposis had recurrent desmoid tumours in the left subclavicular site. Histological examination showed a typical desmoid tumour. Molecular analysis was...
Sakai, K, Ren, S, Schwartz, L B
Tryptase is the major protein constituent of human mast cells, where it is stored within the secretory granules as a fully active tetramer. Two tryptase genes (alpha and beta) are expressed by human...
Harazono, K., Kondo, R., Sakai, K.
In vitro bleaching of an unbleached hardwood kraft pulp was performed with partially purified manganese peroxidase (MnP) from the fungus Phanerochaete sordida YK-624 without the addition of...
Comparison of Pressure Resistances of Spores of Six Bacillus Strains with Their Heat Resistances
Nakayama, A., Yano, Y., Kobayashi, S., Ishikawa, M., Sakai, K.
The pressure resistances of the spores of six Bacillus strains were examined at 5 to 10(deg)C and were compared with their heat resistances. The pressure treatments (at 981 MPa for 40 min and at 588...
Nagata, E, Sakai, K, Kinoshita, H, Kobayashi, Y
An anomalous connection between the choledochus and the pancreatic duct may be associated etiologically or pathogenetically with congenital biliary dilation and carcinoma of the dilated bile duct....
Crossover Interference in Saccharomyces cerevisiae Requires a TID1/RDH54- and DMC1-Dependent Pathway
Activity of primate inferotemporal neurons related to a sought target in pair-association task.
Naya, Y, Sakai, K, Miyashita, Y
Visual long-term memory in primates has been assessed by using the pair-association (PA) task, in which a subject retrieves and chooses the paired associate of a cue picture. Our previous studies on...
Roychoudhury, S, Sakai, K, Chakrabarty, A M
The exopolysaccharide alginate is a major virulence factor in the pathogenicity of Pseudomonas aeruginosa infecting the lungs of cystic fibrosis (CF) patients. Alginate synthesis by P. aeruginosa is...
Takada, S, Nakamura, M, Matsueda, T, Kondo, R, Sakai, K
A method for the degradation of dioxins by white rot fungi was developed. Degradation of a mixture of 10 kinds of tetra- to octachlorodibenzo-p-dioxins (polychlorinated dibenzo-p-dioxins [PCDDs]) and...
Sakai, K, Oshima, K, Moriguchi, M
N-Acyl-D-glutamate amidohydrolase from Pseudomonas sp. strain 5f-1 was inducibly produced by D isomers of N-acetylglutamate, glutamate, aspartate, and asparagine. The enzyme has been purified to...
Schwartz, L B, Sakai, K, Bradford, T R, Ren, S, Zweiman, B, Worobec, A S, ...
Tryptase, a protease produced by all mast cells, was evaluated as a clinical marker of systemic mastocytosis. Two sandwich immunoassays were evaluated, one which used the mAb G5 for capture, the...
Sakai, K, Narihara, M, Kasama, Y, Wakayama, M, Moriguchi, M
Thermostable exochitinase was purified to homogeneity from the culture fluid of Bacillus stearothermophilus CH-4, which was isolated from agricultural compost containing shrimp and crabs. The enzyme...
Sakai, K, Ma, X Y, Gordienko, I, Volsky, D J
Two molecularly cloned coisolates of human immunodeficiency virus type 1 (HIV-1) have been found to exhibit different phenotypes of viral expression, either rapid and cytopathic (N1T-A virus) or...
Sakai, K, Dewhurst, S, Ma, X Y, Volsky, D J
A cytopathic human immunodeficiency virus type 1 (HIV-1) isolate containing multiple virus genotypes was molecularly cloned, and the biological activity of six randomly selected clones was assessed...
Adachi, A, Sakai, K, Kitamura, N, Nakanishi, S, Niwa, O, Matsuyama, M, ...
The highly oncogenic erythroleukemia-inducing Friend mink cell focus-inducing (MCF) virus was molecularly cloned in phage lambda gtWES.lambda B, and the DNA sequences of the env gene and the long...
Dewhurst, S, Sakai, K, Bresser, J, Stevenson, M, Evinger-Hodges, M J, Volsky, D J
The nature of the interaction between human immunodeficiency virus (HIV) and human cells of astrocytic origin was studied in vitro with cultured glial cells and intact HIV or infectious molecular...
Sakai, K, Narita, H, Adachi, A, Tsuruta, S, Yorifuji, T, Ishimoto, A
By a biological assay system using phenotypically mixed ecotropic and xenotropic murine leukemia viruses, we investigated whether in the virions of a xenotropic virus there is N- or B-tropic Fv-1...
Sakai, K, Sinha, A A, Mitchell, D J, Zamvil, S S, Rothbard, J B, McDevitt, H O, ...
The peptide p89-101 (Val-His-Phe-Phe-Lys-Asn-Ile-Val-Thr-Pro-Arg-Thr-Pro) of myelin basic protein is encephalitogenic in mice expressing H-2q and H-2s antigens. Six of 13 encephalitogen-specific...
Sakai, K, Zamvil, S S, Mitchell, D J, Hodgkinson, S, Rothbard, J B, Steinman, L
Two synthetic immunodominant and nonencephalitogenic peptides of myelin basic protein, N1-20 and AcN9-20, effectively compete with an encephalitogenic peptide, AcN1-11, in an in vitro T-cell response...
Yamamura, Y, Hattori, T, Obaru, K, Sakai, K, Asou, N, Takatsuki, K, ...
The gene coding for the protein LD78 was isolated from stimulated human tonsillar lymphocytes by differential hybridization. The gene product consisted of 92 amino acids with characteristics of...
Two RFLPs identified by a human chromosome #2 clone at 2p15-2p16 (HGM8 assignment no. D2S5).
Shiloh, Y, Kanda, N, Kunkel, L M, Bruns, G, Sakai, K, Latt, S A
Sakai, K, Sakaguchi, J, Yamamoto, M
We have developed a high-frequency cotransformation system which is useful in introducing nonreplicating circular DNA plasmids into the fission yeast Schizosaccharomyces pombe. This system depends on...
Biological and Chemical Detection of Trichothecene Mycotoxins of Fusarium Species
Ueno, Y., Sato, N., Ishii, K., Sakai, K., Tsunoda, H., Enomoto, M.
The procedure for biological and chemical detection of trichothecene-type mycotoxins and its application to the screening of Fusarium for toxic strains were described.
Shiloh, Y, Shipley, J, Brodeur, G M, Bruns, G, Korf, B, Donlon, T, ...
DNA amplification, manifested by homogeneously staining regions in chromosomes and by extrachromosomal, double minute bodies, is characteristic of many neuroblastoma cell lines. Sequences recruited...
A novel case of a sporadic desmoid tumour with mutation of the beta catenin gene.
Shitoh, K, Konishi, F, Iijima, T, Ohdaira, T, Sakai, K, Kanazawa, K, ...
A 42 year old man without familial adenomatous polyposis had recurrent desmoid tumours in the left subclavicular site. Histological examination showed a typical desmoid tumour. Molecular analysis was...
Sakai, K, Ren, S, Schwartz, L B
Tryptase is the major protein constituent of human mast cells, where it is stored within the secretory granules as a fully active tetramer. Two tryptase genes (alpha and beta) are expressed by human...
Nagata, E, Sakai, K, Kinoshita, H, Kobayashi, Y
An anomalous connection between the choledochus and the pancreatic duct may be associated etiologically or pathogenetically with congenital biliary dilation and carcinoma of the dilated bile duct....
Harazono, K., Kondo, R., Sakai, K.
In vitro bleaching of an unbleached hardwood kraft pulp was performed with partially purified manganese peroxidase (MnP) from the fungus Phanerochaete sordida YK-624 without the addition of...
Comparison of Pressure Resistances of Spores of Six Bacillus Strains with Their Heat Resistances
Nakayama, A., Yano, Y., Kobayashi, S., Ishikawa, M., Sakai, K.
The pressure resistances of the spores of six Bacillus strains were examined at 5 to 10(deg)C and were compared with their heat resistances. The pressure treatments (at 981 MPa for 40 min and at 588...
Crossover Interference in Saccharomyces cerevisiae Requires a TID1/RDH54- and DMC1-Dependent Pathway
Cyclic adenosine 3',5'-monophosphate metabolism in activated T-cell clones.
Oksenberg, D, Oksenberg, J R, Sakai, K, Peroutka, S J, Steinman, L
The role of cAMP in lymphocyte proliferation was investigated in the response of a monoclonal T-cell population to a specific antigen and compared to the response to interleukin-2 (IL-2) and...
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs
Okazaki, Y, Furuno, M, Kasukawa, T, Adachi, J, Bono, H, Kondo, S, ...
Only a small proportion of the mouse genome is transcribed into mature messenger RNA transcripts. There is an international collaborative effort to identify all full-length mRNA transcripts from the...
Inactivation of C1 in rheumatoid synovial fluid, purified C1 and C1 esterase, by gold compounds*
Schultz, D. R., Volanakis, J. E., Arnold, Patricia I., Gottlieb, N. L., Sakai, K., Stroud, R. M.
The effects of gold compounds on the functional activities of rheumatoid synovial fluid and normal serum Cl, C4, and C2 were investigated in vitro. Commercial and purified gold sodium thiomalate in...
Effect of different sensitizing doses of antigen in a murine model of atopic asthma
Sakai, K, Yokoyama, A, Kohno, N, Hiwada, K
The dose of antigen is assumed to be one of the important factors in the polarized development of helper T cell subsets, i.e. Th1 or Th2 cells. We investigated the effect of the sensitizing antigen...
1. The effect of compound 48/80 on the rat femoral vasculature was examined by means of a cross-circulation technique. 2. Intra-arterial injection of increasing doses (1.5 to 15 microgram) of...
Koga, T., Shiraki, Y., Sakai, K.
1. Positive inotropic responses to alpha- and beta-adrenoceptor agonists of isolated papillary muscles from the tree shrew (Tupaia), were compared with those from guinea-pigs. 2. In Tupaia, the...
Nicorandil attenuates myocardial acidosis during coronary occlusion in dogs.
Abiko, Y., Nishimura, T., Sakai, K.
In dogs anaesthetized with pentobarbitone, the left anterior descending coronary artery (LAD) was partially occluded. Before and 30 min after partial occlusion, the myocardial pH was 7.52-7.54 and...
Sakai, K., Shiraki, Y., Tatsumi, T., Tsuji, K.
1. Contractions to 5-hydroxytryptamine (5-HT) and histamine of longitudinal muscle from the isolated ileum of the tree shrew (Tupaia), guinea-pig and rat were investigated by constructing...
1. The mode of action of histamine was investigated on the rat isolated small intestine perfused at a fixed flow rate through the superior mesenteric artery with blood from the carotid artery of a...
1 Experiments were carried out on rat isolated heart preparations in which the coronary vasculature was perfused through the aorta at a constant flow rate with arterial blood from donor animals....
Conformation and stability of thiol-modified bovine beta-lactoglobulin.
Sakai, K., Sakurai, K., Sakai, M., Hoshino, M., Goto, Y.
Bovine beta-lactoglobulin A assumes a dimeric native conformation at neutral pH, while the conformation at pH 2 is monomeric but still native. Beta-lactoglobulin A has a free thiol at Cys121, which...
Neuropathological studies of the spinal cord in early stage HTLV-I-associated myelopathy (HAM).
Yoshioka, A, Hirose, G, Ueda, Y, Nishimura, Y, Sakai, K
Necropsy findings for a patient with HTLV-I-associated myelopathy (HAM) of 9 months clinical duration are reported. Loss of myelin sheaths and axons together with perivascular lymphocytic...
Sakurai, Y, Sakai, K, Sakuta, M, Iwata, M
The case is described of a patient with alexia and agraphia for kanji, and severe anomia after a subcortical haemorrhage in the left posterior inferior temporal area. Magnetic resonance imaging at...
A full genome scan for gastric cancer
Aoki, M, Yamamoto, K, Noshiro, H, Sakai, K, Yokota, J, Kohno, T, ...
Urinary kallikrein excretion in children of parents with essential hypertension.
Uchiyama, M, Otsuka, T, Sakai, K
Twelve hour urinary kallikrein excretion was measured in 18 healthy children of parents with essential hypertension and in 47 healthy children of parents without this disorder. No statistically...
Cografts of Adrenal Medulla With Pretransected Peripheral Nerve
Date, I., Sakai, K., Hoshimoto, Y., Furuta, T., Asari, S., Ohmoto, T.
Phosphorothioate oligonucleotides, suramin and heparin inhibit DNA-dependent protein kinase activity
Hosoi, Y, Matsumoto, Y, Tomita, M, Enomoto, A, Morita, A, Sakai, K, ...
Phosphorothioate oligonucleotides and suramin bind to heparin binding proteins including DNA polymerases, and inhibit their functions. In the present study, we report inhibition of DNA-dependent...