K. Sakata

Publication List Details

Period

1989 - 2008

Number

61

Co-Authors

The impact of cardiovascular risk factors on the age-related excess risk of coronary heart disease (2006)

Huxley, R, Barzi, F, Lam, TH, Lawes, CMM, Wong, JW, Woodward, M, ...

Purpose Differences in cardiovascular risk factor levels have been suggested to contribute to the age-related excess risk of coronary heart disease (CHD). The aim of this study was to reliably...

The impact of cardiovascular risk factors on the age-related excess risk of coronary heart disease (2006)

Huxley, R, Barzi, F, Lam, TH, Lawes, CMM, Wong, JW, Woodward, M, ...

Purpose Differences in cardiovascular risk factor levels have been suggested to contribute to the age-related excess risk of coronary heart disease (CHD). The aim of this study was to reliably...

Smoking, quitting, and the risk of cardiovascular disease among women and men in the Asia-Pacific region (2005)

Woodward, M., Lam, T. H., Barzi, Federica, Patel, Ashvin K., Gu, D. F., Rodgers, A., ...

Published by Oxford University Press on behalf of the International Epidemiological Association © The Author 2005; all rights reserved.

Smoking, quitting, and the risk of cardiovascular disease among women and men in the Asia-Pacific region (2005)

Woodward, M., Lam, T. H., Barzi, Federica, Patel, Ashvin K., Gu, D. F., Rodgers, A., ...

Published by Oxford University Press on behalf of the International Epidemiological Association © The Author 2005; all rights reserved.

Body mass index and cardiovascular disease in the Asia-Pacific Region: an overview of 33 cohorts involving 310 000 participants (2004)

Mhurchu, CN, Rodgers, A, Pan, WH, Gu, DF, Woodward, M, Parag, V, ...

Background Few prospective data from the Asia-Pacific region are available relating body mass index (BMI) to the risks of stroke and ischaemic heart disease (IHD). Our objective was to assess the...

Blood glucose and risk of cardiovascular disease in the Asia Pacific region (2004)

Lawes, CMM, Parag, V, Bennett, DA, Suh, I, Lam, TH, Whitlock, G, ...

OBJECTIVE - To assess the shape and strength of the association between usual blood glucose and cardiovascular disease (CVD) in Asian and Australasian cohorts and to determine the impact of adjusting...

Technical session 6 : chemistry of quality improvement & value addition (2004)

Yamanish, T., Hazarik, M., Sakata, K., Vasisht, K., Raghavan, K.V.

This item was scanned with a HP 4850 Scanjet at 300 dpi and consists of 24 pages.

Body mass index and cardiovascular disease in the Asia-Pacific Region: an overview of 33 cohorts involving 310 000 participants (2004)

Mhurchu, CN, Rodgers, A, Pan, WH, Gu, DF, Parag, V, Lin, R, ...

Background Few prospective data from the Asia-Pacific region are available relating body mass index (BMI) to the risks of stroke and ischaemic heart disease (IHD). Our objective was to assess the...

Blood glucose and risk of cardiovascular disease in the Asia Pacific region (2004)

Lawes, CMM, Parag, V, Bennett, DA, Suh, I, Whitlock, G, Barzi, F, ...

OBJECTIVE - To assess the shape and strength of the association between usual blood glucose and cardiovascular disease (CVD) in Asian and Australasian cohorts and to determine the impact of adjusting...

Technical session 6 : chemistry of quality improvement & value addition (2004)

Yamanish, T., Hazarik, M., Sakata, K., Vasisht, K., Raghavan, K.V.

This item was scanned with a HP 4850 Scanjet at 300 dpi and consists of 24 pages.

Preparation of Composite Spherical Al-Y2O3 Powders by the Mechanical Shock Method and their Plasma Spray Application. (1998)

Sakata, K., Ogawa, K., Isoda, Y., Homma, K., Tokushima, T.

Composite spherical powders made of aluminum and yttria were prepared by the mechanical shock method. This unique idea for composite powder products, without the use of heat, and making use of the...

The role of the fibrinolytic system in acute myocardial infarction after a normal exercise test (1989)

SAKATA, K., KURATA, C., TAGUCHI, T., HAYASHI, H., KOBAYASHI, A., YAMAZAKI, N., ...

A 67-year-old man had an acute myocardial infarction with thrombosis in the left anterior descending artery shortly after normal exercise. We were able to measure the fibrinolytic components in this...

Fine structure of influenza A virus observed by electron cryo-microscopy.

Fujiyoshi, Y, Kume, N P, Sakata, K, Sato, S B

A rapidly frozen vitrified aqueous suspension of influenza A virus was observed by high resolution electron cryomicroscopy. The influenza particles were grouped into small (diameter < 150 nm)...

Properties of a polyamine transporter regulated by antizyme.

Sakata, K, Kashiwagi, K, Igarashi, K

The regulation of polyamine transport by antizyme, a protein that is involved in the rapid degradation of ornithine decarboxylase (ODC), was studied in FM3A mouse cells overproducing ODC. Both...

Cloning of a lymphatic peptide/histidine transporter.

Sakata, K, Yamashita, T, Maeda, M, Moriyama, Y, Shimada, S, Tohyama, M

Although peptide transport across the plasma membrane has been characterized well in the kidney and the intestine, the functional relevance of this transport in other organs has not been addressed....

Echo-Doppler evaluation of reverse flow sign in the intrahepatic portal branches after surgery.

Nishihara, K, Yagyu, T, Sakata, K, Nakashima, K, Suzuki, T

OBJECTIVE: The author's evaluated the clinical significance of the development of reversed portal flow after abdominal surgery other than portosystemic shunt procedure. SUMMARY BACKGROUND DATA: There...

Fine structure of influenza A virus observed by electron cryo-microscopy.

Fujiyoshi, Y, Kume, N P, Sakata, K, Sato, S B

A rapidly frozen vitrified aqueous suspension of influenza A virus was observed by high resolution electron cryomicroscopy. The influenza particles were grouped into small (diameter < 150 nm)...

Properties of a polyamine transporter regulated by antizyme.

Sakata, K, Kashiwagi, K, Igarashi, K

The regulation of polyamine transport by antizyme, a protein that is involved in the rapid degradation of ornithine decarboxylase (ODC), was studied in FM3A mouse cells overproducing ODC. Both...

Cloning of a lymphatic peptide/histidine transporter.

Sakata, K, Yamashita, T, Maeda, M, Moriyama, Y, Shimada, S, Tohyama, M

Although peptide transport across the plasma membrane has been characterized well in the kidney and the intestine, the functional relevance of this transport in other organs has not been addressed....

Echo-Doppler evaluation of reverse flow sign in the intrahepatic portal branches after surgery.

Nishihara, K, Yagyu, T, Sakata, K, Nakashima, K, Suzuki, T

OBJECTIVE: The author's evaluated the clinical significance of the development of reversed portal flow after abdominal surgery other than portosystemic shunt procedure. SUMMARY BACKGROUND DATA: There...

Dexamethasone suppresses concanavalin A-induced production of chemotactic lymphokines by releasing a soluble factor from splenic T lymphocytes.

Hirashima, M, Sakata, K, Tashiro, K, Yoshimura, T, Hayashi, H

Treatment of guinea-pig spleen cells with glucocorticoids, such as dexamethasone (DEX), reduces concanavalin A (Con A)-induced production of chemotactic lymphokines (CLK), such as eosinophil...

The regulation of tissue eosinophilia. III. In vitro production of eosinophil-directed chemotactic inhibitory factor by T lymphocytes of complete Freund's adjuvant-treated guinea-pigs.

Tashiro, K, Sakata, K, Hirashima, M, Hayashi, H

Guinea-pig spleen cells treated with complete Freund's adjuvant (CFA) produce eosinophil-directed chemotactic inhibitory factors (ECIF). The inhibition is selective for the response of eosinophils to...

A comparison of lipid variables as predictors of cardiovascular disease in the Asia Pacific Region

Barzi, F, Patel, A, Woodward, M, Lawes, CMM, Ohkubo, T, Gu, D, ...

PURPOSE: Many guidelines advocate measurement of total or low density lipoprotein cholesterol (LDL), high density lipoprotein cholesterol (HDL), and triglycerides (TG) to determine treatment...

Smoking, quitting, and the risk of cardiovascular disease among women and men in the Asia-Pacific region

Woodward, M, Lam, TH, Barzi, F, Patel, A, Gu, D, Rodgers, A, ...

Background Although smoking is a major risk factor for cardiovascular disease, it has been suggested that Asians may be less susceptible to the adverse effects of smoking than Caucasians. This may...

Does sex matter in the associations between classic risk factors and fatal coronary heart disease in populations from the Asia-Pacific region?

Huxley, R, Woodward, M, Barzi, F, Wong, JW, Pan, WH, Patel, A, ...

Background: There is much interest in promoting healthy heart awareness among women. However, little is known about the reasons behind the lower rates of heart disease among women compared with men,...

Coronary risk prediction for those with and without diabetes

Woodward, M, Barzi, E, Lam, TH, Jamrozik, K, Ueshima, H, Patel, A, ...

Background Coronary risk prediction 'engines' are now in common use, and their worth is well proven. There remains the question of how to deal with a prior diagnosis of diabetes. Design An individual...

Body mass index and risk of diabetes mellitus in the Asia-Pacific region

Mhurchu, CN, Parag, V, Nakamura, M, Patel, A, Rodgers, A, Lam, TH, ...

Few prospective data from the Asia Pacific region are available relating body mass index to the risk of diabetes. Our objective was to provide reliable age, sex and region specific estimates of the...

QT dispersion and left ventricular morphology in patients with hypertrophic cardiomyopathy

Sakata, K, Shimizu, M, Ino, H, Yamaguchi, M, Terai, H, Hayashi, K, ...

Objective: To evaluate the relation between QT variables and disproportion of left ventricular wall hypertrophy in patients with hypertrophic cardiomyopathy.

Isolation of an eosinophil chemotactic lymphokine as a natural mediator for eosinophil chemotaxis from concanavalin A-induced skin reaction sites in guinea-pigs.

Hirashima, M, Tashiro, K, Sakata, K, Hirashima, M

An intradermal injection with 20 micrograms concanavalin A (Con A) induce a marked tissue eosinophilia peaking at 24 h after the injection in guinea-pigs. Two different eosinophil chemotactic factors...

Characterization of fertilization-blocking monoclonal antibody 1G12 with human sperm-immobilizing activity

KOMORI, S, KAMEDA, K, SAKATA, K, HASEGAWA, A, TOJI, H, TSUJI, Y, ...

A mouse hybridoma (1G12) producing sperm-immobilizing MoAb to human sperm was established and characterized in order to study the antigens relevant to sperm immobilization by antibodies. MoAb 1G12...

Risk evaluation of outcome of vitreous surgery for proliferative diabetic retinopathy based on vitreous level of vascular endothelial growth factor and angiotensin II

Funatsu, H, Yamashita, H, Noma, H, Mimura, T, Sakata, K, Hori, S

Aims: To ascertain whether measurement of the vitreous fluid levels of vascular endothelial growth factor (VEGF) or angiotensin II (Ang II) could predict the outcome of vitreous surgery in patients...

Effects of endothelin on the mechanical activity and cytosolic calcium level of various types of smooth muscle.

Sakata, K., Ozaki, H., Kwon, S. C., Karaki, H.

1. Effects of porcine/human endothelin (endothelin-1), a novel vasoconstrictor peptide, on various smooth muscles were examined. 2. In rat aorta, endothelin (1 pM-30nM) induced contraction in a...

Inhibition of calcium channels by harmaline and other harmala alkaloids in vascular and intestinal smooth muscles.

Karaki, H., Kishimoto, T., Ozaki, H., Sakata, K., Umeno, H., Urakawa, N.

Effects of harmaline and other harmala alkaloids on the contractions induced in the vascular smooth muscle of rabbit aorta and intestinal smooth muscle of taenia isolated from guinea-pig caecum were...

Effects of a novel smooth muscle relaxant, KT-362, on contraction and cytosolic Ca2+ level in the rat aorta.

Sakata, K., Karaki, H.

1. Inhibitory effects of a novel smooth muscle relaxant, KT-362 (5-[3-([2-(3,4-dimethoxyphenyl)-ethyl]amino)-1-oxopropyl]-2,3,4,5- tetrahydro-1,5-benzothiazepine fumarate), on contraction and the...

Successful induction of severe destructive arthritis by the transfer of in vitro-activated synovial fluid T cells from patients with rheumatoid arthritis (RA) in severe combined immunodeficient (SCID) mice

SAKATA, A, SAKATA, K, PING, H, OHMURA, T, TSUKANO, M, KAKIMOTO, K

In order to investigate the role of pathogenic T cells in RA, the establishment of an RA model using patients’ T cells is thought to be essential. In this study, multiple and severe destructive...

Gastric cancer screening programme in Japan: how to improve its implementation in the community.

Wang, B, Yanagawa, H, Sakata, K

STUDY OBJECTIVE--The aim was to investigate which factors in the operating procedure of the gastric cancer screening programme carried out by local Japanese municipalities affect the participation...

Involvement of retinoic acid-inducible gene-I in inflammation of rheumatoid fibroblast-like synoviocytes

Imaizumi, T, Arikawa, T, Sato, T, Uesato, R, Matsumiya, T, Yoshida, H, ...

Interferon (IFN)-γ is a major cytokine that regulates T helper 1-type immune reactions and serves as an important mediator in the pathogenesis of autoimmune diseases. Retinoic acid-inducible gene-I...

Hypoxia-induced drug resistance: comparison to P-glycoprotein-associated drug resistance.

Sakata, K., Kwok, T. T., Murphy, B. J., Laderoute, K. R., Gordon, G. R., Sutherland, R. M.

In this report, we investigate several examples of hypoxia-induced drug resistance and compare them with P-glycoprotein associated multidrug resistance (MDR). EMT6/Ro cells exposed to drugs in air...

Adenomatous polyposis coli (APC) gene promoter hypermethylation in primary breast cancers

Jin, Z, Tamura, G, Tsuchiya, T, Sakata, K, Kashiwaba, M, Osakabe, M, ...

Similar to findings in colorectal cancers, it has been suggested that disruption of the adenomatous polyposis coli (APC)/β-catenin pathway may be involved in breast carcinogenesis. However, somatic...

A prospective study of stomach cancer death in relation to green tea consumption in Japan

Hoshiyama, Y, Kawaguchi, T, Miura, Y, Mizoue, T, Tokui, N, Yatsuya, H, ...

To evaluate whether green tea consumption provides protection against stomach cancer death, relative risks were calculated using Cox proportional hazards regression analysis in the Japan...

Hypermethylation of the hMLH1 gene promoter in solitary and multiple gastric cancers with microsatellite instability

Sakata, K, Tamura, G, Endoh, Y, Ohmura, K, Ogata, S, Motoyama, T

Human cancers with a high frequency microsatellite instability phenotype develop due to defects in DNA mismatch repair genes. Silencing of a DNA mismatch repair gene, hMLH1 gene, by promoter...