K. Schmiegelow

Publication List Details

Period

1986 - 2009

Number

17

Co-Authors

Cellular drug sensitivity in MLL-rearranged childhood acute leukaemia is correlated to partner genes and cell lineage (2005)

Palle, J, Frost, B M, Forestier, E, Gustafsson, G, Nygren, P, Hellebostad, M, ...

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Safe treatment of thiopurine S-methyltransferase deficient Crohn's disease patients with azathioprine (2003)

Kaskas, BA, Louis, Edouard, Hindorf, U, Schaeffeler, E, Deflandre, Jean-Luc, Graepler, F, ...

Thiopurine S-methyltransferase (TPMT) deficient patients develop life threatening haematoxicity (for example, pancytopenia) when treated with a standard dose of azathioprine (AZA) and...

Diminished ovarian reserve in female childhood cancer survivors with regular menstrual cycles and basal FSH (2003)

Larsen, E.C., Müller, J., Rechnitzer, C., Schmiegelow, K., Andersen, A.Nyboe

BACKGROUND: Approximately 70% of children treated for cancer are cured, however the treatment often impairs reproductive function. The aim of the present study was to assess ovarian reserve in...

Linkage of cystic fibrosis to the proα2(I) collagen gene, COL1A2, on chromosome 7 (1986)

Buchwald, M, Zsiga, M, Markiewicz, D, Plavsic, N, Kennedy, D, Zengerling, S, ...

A linkage has been detected between the locus for cystic fibrosis (CF) and the proα2(I) collagen gene (COL1A2) which is located in the region q21.3→q22.1 of chromosome 7. Based on the combined...

Linkage between the loci for cystic fibrosis and paraoxonase (1986)

Schmiegelow, K, Eiberg, H, Tsui, L-C, Buchwald, M, Phelan, PD, Williamson, R, ...

In a material of 22 Danish, 26 Canadian, 10 Australian, 5 English and 5 American families with at least 2 children affected with cystic fibrosis (CF) a combined positive LOD score of 3.46 was found...

6-Thioguanine nucleotide accumulation in erythrocytes during azathioprine treatment for systemic connective tissue diseases: a possible index for monitoring treatment.

Schmiegelow, K, Kriegbaum, N J

BACKGROUND: Owing to adverse pharmacokinetics, azathioprine treatment may fail to induce a satisfactory clinical response in systemic connective tissue diseases. The major intracellular cytotoxic...

Safe treatment of thiopurine S-methyltransferase deficient Crohn’s disease patients with azathioprine

Kaskas, B A, Louis, E, Hindorf, U, Schaeffeler, E, Deflandre, J, Graepler, F, ...

Thiopurine S-methyltransferase (TPMT) deficient patients develop life threatening haematotoxicity (for example, pancytopenia) when treated with a standard dose of azathioprine (AZA) and...

Prognostic significance of hepatotoxicity during maintenance chemotherapy for childhood acute lymphoblastic leukaemia.

Schmiegelow, K., Pulczynska, M.

In a population-based study of 115 children with non-B-cell acute lymphoblastic leukaemia, we analysed the relation of the degree of leukopenia and risk of relapse to the degree of hepatotoxicity (as...

Increasing incidence of childhood tumours of the central nervous system in Denmark, 1980–1996

Raaschou-Nielsen, O, Sørensen, M, Carstensen, H, Jensen, T, Bernhardtsen, T, Gjerris, F, ...

The registered incidence rate of childhood central nervous system (CNS) tumours has increased in several countries. It is uncertain whether these increases are biologically real or owing to improved...

Presence of clone-specific markers at birth in children with acute lymphoblastic leukaemia

Hjalgrim, L L, Madsen, H O, Melbye, M, Jørgensen, P, Christiansen, M, Andersen, M T, ...

Recent studies have suggested that development of childhood acute lymphoblastic leukaemia may often be initiated in utero. To provide further evidence of an prenatal origin of childhood leukaemia, we...