Hida, S, Yamasaki, S, Sakamoto, Y, Takamoto, M, Obata, K, Takai, T, ...
Takamoto, M, Wang, Z X, Watanabe, N, Matsuzawa, A, Nariuchi, H, Sugane, K
Mutant mice deficient in CD4+ T cells and their normal and heterozygous littermates were infected with Toxocara canis, and compared for eosinophilia, total and Toxocara-specific immunoglobulin E...
Takamoto, M, Isobe, M, Sugane, K
In order to study the effect of costimulatory signals on T helper type 2 (Th2) cytokine production, monoclonal antibodies (mAb) against cell adhesion molecules (CAM) were added to cells in culture...
Takamoto, M, Kusama, Y, Takatsu, K, Nariuchi, H, Sugane, K
We studied cells in the lungs of BALB/c and BALB/c-nu/nu (nude) mice infected with Toxocara canis, which produced interleukin-5 (IL-5) in in vitro culture with larval excretory-secretory antigen...
Kusama, Y, Takamoto, M, Kasahara, T, Takatsu, K, Nariuchi, H, Sugane, K
We studied the mechanism of eosinophilia in BALB/c-nu/+ (nu/+) and BALB/c-nu/nu (nu/nu) mice infected with Toxocara canis. Eosinophilia with two peaks on days 11 and 21 of infection was observed in...
Purification and characterization of excretory and secretory antigen of Toxocara canis larvae.
Excretory/secretory (ES) antigen of Toxocara canis larvae was isolated from the culture medium of second-stage larvae by gel filtration. The antigen induced production of not only IgM or IgG but also...
Takamoto, M, Ovington, K S, Behm, C A, Sugane, K, Young, I G, Matthaei, K I
C57Bl/6 mice genetically deficient in interleukin (IL)-5 (IL-5-/-) and mice with the normal IL-5 gene (IL-5+/+) were infected with embryonated eggs of Toxocara canis. IL-5+/+ mice developed a marked...
Hokibara, S, Takamoto, M, Isobe, M, Sugane, K
Eosinophilic myocarditis followed by fibrosis of the cardiac muscle was observed in addition to peripheral blood eosinophilia in CBA/J mice infected with Toxocara canis. The infected mice were used...