Ruppert, C., Mahavadi, P., Wygrecka, M., Weaver, T.E., Magdolen, V., Idell, S., ...
Intraalveolar fibrin deposition is commonly observed during acute inflammatory and chronic interstitial lung diseases and may contribute to impairment of surfactant function and gas exchange. We...
Kouri, F.M., Queisser, M.A., Konigshoff, M., Chrobak, I., Preissner, K.T., Seeger, W., ...
RATIONALE: Pulmonary arterial smooth muscle cells (PASMCs) in the medial layer of the vessel wall are responsible for vessel homeostasis, but also for pathologic vascular remodelling in diseases,...
Fischer, S., Gerriets, T., Wessels, C., Walberer, M., Kostin, S., Stolz, E., ...
Cell injury leads to exposure of intracellular material and is associated with increased permeability of vessels in the vicinity of the damage. Here, we demonstrate that natural extracellular RNA as...
Flt-1, but not Flk-1 mediates hyperpermeability through activation of the PI3-K/Akt pathway (2007)
Vogel, C., Bauer, A., Wiesnet, M., Preissner, K. T., Schaper, W., Marti, H. H., ...
Vascular endothelial growth factor (VEGF), a potent mediator of endothelial proliferation and migration, has an important role also in brain edema formation during hypoxia and ischemia. VEGF binds to...
Receptor-independent role of the urokinase-type plasminogen activator during arteriogenesis (2003)
Ziegelhöffer, T, Kanse, S M, Fernandez, B, Neubauer, E, ...
To define the role of the plasminogen activators (PAs) urokinase PA (uPA) and tissue PA (tPA) as well as the uPA receptor (uPAR) in arteriogenesis, we investigated their impact in a rabbit and mouse...
Angiogenic capacity of endothelial cells in islets of Langerhans (2003)
Linn, T., Schneider, K., Hammes, H. P., Preissner, K. T., Brandhorst, H., Morgenstern, E., ...
Transplantation of pancreatic islets reconstitutes glucose homeostasis in diabetes mellitus. Before transplantation, islets are disrupted from the surrounding blood vessels by the isolation...
Receptor-independent role of the urokinase-type plasminogen activator during arteriogenesis (2003)
Deindl, E., Ziegelhoffer, T., Kanse, S. M., Fernandez, B., Neubauer, E., Carmeliet, P., ...
To define the role of the plasminogen activators (PAs) urokinase PA (uPA) and tissue PA (tPA) as well as the uPA receptor (uPAR) in arteriogenesis, we investigated their impact in a rabbit and mouse...
Kanse, S M, Yutzy, B, Preissner, K T
Urokinase-type-plasminogen activator (uPA) and its receptor are localized in the vessel wall where they are involved in cellular activation and remodelling processes. Besides the cell surface...
Benzakour, O, Kanthou, C, Kost, C, Preissner, K T
The urokinase-type plasminogen activator (UPA) and its receptor are expressed in the vasculature and are involved in cell migration and remodeling of the extracellular matrix in the neointima....
Nuovo, G.J., Preissner, K.T., Bronson, R.A.
Vitronectin is an adhesion protein present within the acrosomal cap region of human spermatozoa and is liberated during the acrosome reaction. The purpose of this study was to determine if...
Nuovo, G.J., Preissner, K.T., Bronson, R.A.
Vitronectin is an adhesion protein present within the acrosomal cap region of human spermatozoa and is liberated during the acrosome reaction. The purpose of this study was to determine if...
Hess, S, Timpl, R, Preissner, K T
The adhesive glycoprotein vitronectin (VN) shows a high degree of conformational flexibility implicating that different molecular forms of the molecular may exist. Conformation-dependent monoclonal...
Strohscheer, I., Kleinert, R., Westphal, C., Schüller, J., Werner, K., Anders, O., ...
Peer Reviewed
Valentin-Weigand, P, Grulich-Henn, J, Chhatwal, G S, Müller-Berghaus, G, Blobel, H, Preissner, K T
The role of S protein in the adherence of group A and G streptococci to human umbilical vein endothelial cells cultivated in 96-well microdilution plates was studied by utilizing fluorescein-labeled...
Chhatwal, G S, Preissner, K T, Müller-Berghaus, G, Blobel, H
Specific binding of the 125I-labeled human S protein (vitronectin) which has been shown to be identical with serum-spreading factor, was observed with group A, C, and G streptococci as well as with...
Preissner, K T, Zwicker, L, Müller-Berghaus, G
S protein, a plasma glycoprotein with Mr 78,000, has been shown to interfere with the heparin-catalysed inhibition of thrombin by antithrombin III. This interaction was further evaluated in the...
Preissner, K T, Wassmuth, R, Müller-Berghaus, G
S-protein, the main inhibitor of the assembly of the membrane attack complex of complement, was isolated from human plasma by a simple purification procedure, which includes barium citrate...
Rosenblatt, S, Bassuk, J A, Alpers, C E, Sage, E H, Timpl, R, Preissner, K T
Heparin-binding forms of vitronectin, a multifunctional adhesive glycoprotein, are associated with the extracellular matrix (ECM) at different locations in the body and serve to promote cell adhesion...
Valentin-Weigand, P, Grulich-Henn, J, Chhatwal, G S, Müller-Berghaus, G, Blobel, H, Preissner, K T
The role of S protein in the adherence of group A and G streptococci to human umbilical vein endothelial cells cultivated in 96-well microdilution plates was studied by utilizing fluorescein-labeled...
Chhatwal, G S, Preissner, K T, Müller-Berghaus, G, Blobel, H
Specific binding of the 125I-labeled human S protein (vitronectin) which has been shown to be identical with serum-spreading factor, was observed with group A, C, and G streptococci as well as with...
Preissner, K T, Zwicker, L, Müller-Berghaus, G
S protein, a plasma glycoprotein with Mr 78,000, has been shown to interfere with the heparin-catalysed inhibition of thrombin by antithrombin III. This interaction was further evaluated in the...
Preissner, K T, Wassmuth, R, Müller-Berghaus, G
S-protein, the main inhibitor of the assembly of the membrane attack complex of complement, was isolated from human plasma by a simple purification procedure, which includes barium citrate...
Rosenblatt, S, Bassuk, J A, Alpers, C E, Sage, E H, Timpl, R, Preissner, K T
Heparin-binding forms of vitronectin, a multifunctional adhesive glycoprotein, are associated with the extracellular matrix (ECM) at different locations in the body and serve to promote cell adhesion...
Complement S-protein (vitronectin) is associated with cytolytic membrane-bound C5b-9 complexes.
Bhakdi, S, Käflein, R, Halstensen, T S, Hugo, F, Preissner, K T, Mollnes, T E
It has been assumed that S-protein (vitronectin) associates with terminal C5b-9 complement complexes only when the latter fail to attach to target lipid bilayers, thereby forming inactive fluid-phase...