A Graph Spectral Analysis of the Structural Similarity Network of Protein Chains (2008)
O. Krishnadev, K. V. Brinda, Saraswathi Vishveshwara
ABSTRACT We present a simple method for the analysis of large networks based on their graph spectral properties. One of the advantages of this method is that it uses a single numerical computation to...
Dynamics of Lysozyme Structure Network: Probing the Process of Unfolding (2007)
Amit Ghosh, K. V. Brinda, Saraswathi Vishveshwara
ABSTRACT Recently we showed that the three-dimensional structure of proteins can be investigated from a network perspective, where the amino acid residues represent the nodes in the network and the...
Determinants of quaternary association in legume lectins (2004)
Brinda, K.V., Mitra, Nivedita, Surolia, Avadhesha, Vishveshwara, Saraswathi
It is well known that the sequence of amino acids in proteins code for its tertiary structure. It is also known that there exists a relationship between sequence and the quaternary structure of...
Analysis of homodimeric protein interfaces by graph-spectral methods (2002)
Brinda, K.V., Kannan, N., Vishveshwara, S.
The quaternary structures impart structural and functional credibility to proteins. In a multi-subunit protein, it is important to understand the factors that drive the association or dissociation of...
A Network Representation of Protein Structures: Implications for Protein Stability
Brinda, K. V., Vishveshwara, Saraswathi
This study views each protein structure as a network of noncovalent connections between amino acid side chains. Each amino acid in a protein structure is a node, and the strength of the noncovalent...
Dynamics of Lysozyme Structure Network: Probing the Process of Unfolding
Ghosh, Amit, Brinda, K. V., Vishveshwara, Saraswathi
Recently we showed that the three-dimensional structure of proteins can be investigated from a network perspective, where the amino acid residues represent the nodes in the network and the...
Determinants of quaternary association in legume lectins
Brinda, K.V., Mitra, Nivedita, Surolia, Avadhesha, Vishveshwara, Saraswathi
It is well known that the sequence of amino acids in proteins code for its tertiary structure. It is also known that there exists a relationship between sequence and the quaternary structure of...