K. Venkateswarlu

Publication List Details

Period

1956 - 2008

Number

44

Co-Authors

On the feasibility of using a continuous processing technique incorporating a limited strain imposed by ECAP (2007)

Venkateswarlu, K., Ghosh, M., Ray, A.K., Xu, C., Langdon, T.G.

Equal-channel angular pressing (ECAP) is used extensively in many laboratories for the production of metallic alloys having grain sizes in the submicrometer or nanometer range. However, the ECAP...

Using ball-indentation to evaluate the properties of an unltrafine-grained Al-2% Si Alloy processed by ECAP (2006)

Venkateswarlu, K., Das, Gautam, Pramanik, A.K., Xu, Cheng, Langdon, Terence G.

As-cast Al–Si alloys exhibit excellent mechanical properties but these properties may be further improved through processing by equal-channel angular pressing (ECAP). In this investigation,...

Basement configuration of Visakhapatnam - Paradip continental margin from inversion of magnetic anomalies (2000)

Rao, M.M.M., Rao, S.J., Venkateswarlu, K., Murthy, K.S.R., Murthy, I.V.R., Subrahmanyam, A.S.

Inversion of magnetic data was carried out on 40 profiles collected across the continental margin of Visakhapatnam, Andhra Pradesh, India at a spacing of about 10 km and magnetic basement map for...

Oil Throw and Wear Reduction in a Deep Freezer Compressor (1995)

Kale, S R, Dhar, P L, Agarwal, R S, Athre, K, Biswas, S, Venkateswarlu, K, ...

The design methodologies for reducing operational problems in a hermetically sealed single-cylinder R-12 compressor used in deep freezers are discussed. Excessive oil throw was reduced to acceptable...

Évaluation des constantes de forces d'après les données de l'effet Raman : molécules de type XY3Z (1956)

Venkateswarlu, K., Sundaram, S.

Les constantes de forces des molécules POCl3, POBr3, PSCl3, SiHCl3, SiHBr3, SnBrCl3, SnClBr3 et SiClBr3, toutes du type XY3Z, ont été calculées par la méthode des matrices F-G de Wilson. Dans...

Évaluation des constantes de forces d'après les données de l'effet Raman : molécules de type XY3Z (1956)

Venkateswarlu, K., Sundaram, S.

Les constantes de forces des molécules POCl3, POBr3, PSCl3, SiHCl3, SiHBr3, SnBrCl3, SnClBr3 et SiClBr3, toutes du type XY3Z, ont été calculées par la méthode des matrices F-G de Wilson. Dans...

Évaluation des constantes de forces d'après les données de l'effet Raman : molécules de type XY3Z (1956)

Venkateswarlu, K., Sundaram, S.

Les constantes de forces des molécules POCl3, POBr3, PSCl3, SiHCl3, SiHBr3, SnBrCl3, SnClBr3 et SiClBr3, toutes du type XY3Z, ont été calculées par la méthode des matrices F-G de Wilson. Dans...

NADPH Cytochrome P-450 Oxidoreductase and Susceptibility to Ketoconazole

Venkateswarlu, K., Kelly, Diane E., Manning, Nigel J., Kelly, Steven L.

The phenotype of a strain of Saccharomyces cerevisiae containing a disruption of the gene encoding NADPH cytochrome P-450 oxidoreductase (CPR) was quantified biochemically and microbiologically, as...

Comparison of D0870, a new triazole antifungal agent, to fluconazole for inhibition of Candida albicans cytochrome P-450 by using in vitro assays.

Venkateswarlu, K, Denning, D W, Manning, N J, Kelly, S L

D0870 was 12 to 15 times more active than fluconazole in experiments to determine the MIC for growth arrest for two isolates of Candida albicans. A biochemical comparison of in vitro sterol...

Reduced accumulation of drug in Candida krusei accounts for itraconazole resistance.

Venkateswarlu, K, Denning, D W, Manning, N J, Kelly, S L

Due to intrinsic resistance Candida krusei is emerging as a systemic pathogen in AIDS patients undergoing fluconazole therapy, but acquired resistance to itraconazole has not been studied...

Fluconazole tolerance in clinical isolates of Cryptococcus neoformans.

Venkateswarlu, K, Taylor, M, Manning, N J, Rinaldi, M G, Kelly, S L

Eleven isolates of Cryptococcus neoformans were investigated to determine the biochemical basis of their tolerance to fluconazole. The MICs of fluconazole for three isolates with low-level resistance...

Characterization of Saccharomyces cerevisiae CYP51 and a CYP51 fusion protein with NADPH cytochrome P-450 oxidoreductase expressed in Escherichia coli.

Venkateswarlu, K, Kelly, D E, Kelly, S L

Saccharomyces cerevisiae CYP51, target of azole antifungal agents, and CYP51 fused with S. cerevisiae cytochrome P-450 oxidoreductase (FUS protein) were expressed in active forms in Escherichia coli...

Itraconazole resistance in Aspergillus fumigatus.

Denning, D W, Venkateswarlu, K, Oakley, K L, Anderson, M J, Manning, N J, Stevens, D A, ...

Invasive aspergillosis is an increasingly frequent opportunistic infection in immunocompromised patients. Only two agents, amphotericin B and itraconazole, are licensed for therapy. Itraconazole acts...

Identification of centaurin-alpha1 as a potential in vivo phosphatidylinositol 3,4,5-trisphosphate-binding protein that is functionally homologous to the yeast ADP-ribosylation factor (ARF) GTPase-activating protein, Gcs1.

Venkateswarlu, K, Oatey, P B, Tavaré, J M, Jackson, T R, Cullen, P J

Centaurin-alpha is a 46 kDa in vitro binding protein for the lipid second messenger PtdIns(3,4,5)P3. In this report we have addressed whether centaurin-alpha1, a human homologue of centaurin-alpha,...

Confocal imaging of the subcellular distribution of phosphatidylinositol 3,4,5-trisphosphate in insulin- and PDGF-stimulated 3T3-L1 adipocytes.

Oatey, P B, Venkateswarlu, K, Williams, A G, Fletcher, L M, Foulstone, E J, Cullen, P J, ...

The activation of phosphatidylinositol 3-kinase (PI 3-kinase) and production of PtdIns(3,4,5)P(3) is crucial in the actions of numerous extracellular stimuli, including insulin-stimulated glucose...

Signalling via ADP-ribosylation factor 6 lies downstream of phosphatidylinositide 3-kinase.

Venkateswarlu, K, Cullen, P J

ADP-ribosylation factor (ARF) 6 regulates plasma membrane trafficking and cortical actin formation by cycling between inactive GDP and active GTP-bound conformations. Here we show that agonist...

Sequences associated with human iris pigmentation.

Frudakis, Tony, Thomas, Matthew, Gaskin, Zach, Venkateswarlu, K, Chandra, K Suresh, Ginjupalli, Siva, ...

To determine whether and how common polymorphisms are associated with natural distributions of iris colors, we surveyed 851 individuals of mainly European descent at 335 SNP loci in 13 pigmentation...

NADPH Cytochrome P-450 Oxidoreductase and Susceptibility to Ketoconazole

Venkateswarlu, K., Kelly, Diane E., Manning, Nigel J., Kelly, Steven L.

The phenotype of a strain of Saccharomyces cerevisiae containing a disruption of the gene encoding NADPH cytochrome P-450 oxidoreductase (CPR) was quantified biochemically and microbiologically, as...

Comparison of D0870, a new triazole antifungal agent, to fluconazole for inhibition of Candida albicans cytochrome P-450 by using in vitro assays.

Venkateswarlu, K, Denning, D W, Manning, N J, Kelly, S L

D0870 was 12 to 15 times more active than fluconazole in experiments to determine the MIC for growth arrest for two isolates of Candida albicans. A biochemical comparison of in vitro sterol...

Reduced accumulation of drug in Candida krusei accounts for itraconazole resistance.

Venkateswarlu, K, Denning, D W, Manning, N J, Kelly, S L

Due to intrinsic resistance Candida krusei is emerging as a systemic pathogen in AIDS patients undergoing fluconazole therapy, but acquired resistance to itraconazole has not been studied...

Fluconazole tolerance in clinical isolates of Cryptococcus neoformans.

Venkateswarlu, K, Taylor, M, Manning, N J, Rinaldi, M G, Kelly, S L

Eleven isolates of Cryptococcus neoformans were investigated to determine the biochemical basis of their tolerance to fluconazole. The MICs of fluconazole for three isolates with low-level resistance...

Characterization of Saccharomyces cerevisiae CYP51 and a CYP51 fusion protein with NADPH cytochrome P-450 oxidoreductase expressed in Escherichia coli.

Venkateswarlu, K, Kelly, D E, Kelly, S L

Saccharomyces cerevisiae CYP51, target of azole antifungal agents, and CYP51 fused with S. cerevisiae cytochrome P-450 oxidoreductase (FUS protein) were expressed in active forms in Escherichia coli...

Itraconazole resistance in Aspergillus fumigatus.

Denning, D W, Venkateswarlu, K, Oakley, K L, Anderson, M J, Manning, N J, Stevens, D A, ...

Invasive aspergillosis is an increasingly frequent opportunistic infection in immunocompromised patients. Only two agents, amphotericin B and itraconazole, are licensed for therapy. Itraconazole acts...

Identification of centaurin-alpha1 as a potential in vivo phosphatidylinositol 3,4,5-trisphosphate-binding protein that is functionally homologous to the yeast ADP-ribosylation factor (ARF) GTPase-activating protein, Gcs1.

Venkateswarlu, K, Oatey, P B, Tavaré, J M, Jackson, T R, Cullen, P J

Centaurin-alpha is a 46 kDa in vitro binding protein for the lipid second messenger PtdIns(3,4,5)P3. In this report we have addressed whether centaurin-alpha1, a human homologue of centaurin-alpha,...

Confocal imaging of the subcellular distribution of phosphatidylinositol 3,4,5-trisphosphate in insulin- and PDGF-stimulated 3T3-L1 adipocytes.

Oatey, P B, Venkateswarlu, K, Williams, A G, Fletcher, L M, Foulstone, E J, Cullen, P J, ...

The activation of phosphatidylinositol 3-kinase (PI 3-kinase) and production of PtdIns(3,4,5)P(3) is crucial in the actions of numerous extracellular stimuli, including insulin-stimulated glucose...

Signalling via ADP-ribosylation factor 6 lies downstream of phosphatidylinositide 3-kinase.

Venkateswarlu, K, Cullen, P J

ADP-ribosylation factor (ARF) 6 regulates plasma membrane trafficking and cortical actin formation by cycling between inactive GDP and active GTP-bound conformations. Here we show that agonist...

Sequences associated with human iris pigmentation.

Frudakis, Tony, Thomas, Matthew, Gaskin, Zach, Venkateswarlu, K, Chandra, K Suresh, Ginjupalli, Siva, ...

To determine whether and how common polymorphisms are associated with natural distributions of iris colors, we surveyed 851 individuals of mainly European descent at 335 SNP loci in 13 pigmentation...

Effects of heptanol on electrical activity in the guinea-pig vas deferens

Manchanda, R, Venkateswarlu, K

The effects of the putative intercellular uncoupling agent 1-heptanol on electrical activity in the guinea-pig vas deferens were studied by use of intracellular and extracellular recording...

Effects of heptanol on the neurogenic and myogenic contractions of the guinea-pig vas deferens

Venkateswarlu, K, Dange, Sumedha Y, Manchanda, Rohit

The effects of the putative gap junction uncoupler, 1-heptanol, on the neurogenic and myogenic contractile responses of guinea-pig vas deferens were studied in vitro.Superfusion of 2.0 mM heptanol...

Quantal evoked depolarizations underlying the excitatory junction potential of the guinea-pig isolated vas deferens

Manchanda, Rohit, Venkateswarlu, K

The effects of a putative gap junction uncoupling agent, heptanol, on the intracellularly recorded junction potentials of the guinea-pig isolated vas deferens have been investigated.After the...

Kocher-Debré-Sémélaigne syndrome and congenital nystagmus

Radhakrishnan, K., Walia, B. N. S., Venkateswarlu, K., Mann, S. B. S.

A 11-year-old boy with hypothyroidism developed generalized muscle hypertrophy and proximal muscular weakness. Electromyographic findings were suggestive of myopathy. He had had congenital nystagmus...