Gale, R.E., Hills, R., Pizzey, A.R., Kottaridis, P.D., Swirsky, D., Gilkes, A.F., ...
The prognostic significance of FLT3 mutations in acute promyelocytic leukemia (APL) is not firmly established and is of particular interest given the opportunities for targeted therapies using FLT3...
Gibson, B.E., Wheatley, K., Hann, I.M., Stevens, R.F., Webb, D., Hills, R.K., ...
Between 1988 and 2002, 758 children with acute myeloid leukaemia (AML) were treated on Medical Research Council (MRC) AML 10 and AML 12. MRC AML 10 tested the role of bone marrow transplantation...
Bowen, D.T., Frew, M.E., Hills, R., Gale, R.E., Wheatley, K., Groves, M.J., ...
The pathogenesis of acute myeloid leukemia (AML) involves the cooperation of mutations promoting proliferation/survival and those impairing differentiation. The RAS pathway has been implicated as a...
Gale, R.E., Hills, R., Kottaridis, P.D., Srirangan, S., Wheatley, K., Burnett, A.K., ...
Fetal liver tyrosine kinase 3 (FLT3) internal tandem duplications (ITDs) are powerful adverse prognostic indicators for relapse in acute myeloid leukemia (AML) but the most efficacious therapy for...
Allan, J.M., Smith, A.G., Wheatley, K., Hills, R.K., Travis, L.B., Hill, D.A., ...
The xeroderma pigmentosum group D (XPD) gene encodes a DNA helicase that functions in nucleotide excision repair of chemotherapy-induced DNA damage, the efficiency of which is predicted to be...
Allan, J.M., Smith, A.G., Wheatley, K., Hills, R.K., Travis, L.B., Hill, D.A., ...
The xeroderma pigmentosum group D (XPD) gene encodes a DNA helicase that functions in nucleotide excision repair of chemotherapy-induced DNA damage, the efficiency of which is predicted to be...
Mizoguchi,T., Wheatley,K., Hanzawa,Y., Wright,L., Mizoguchi,M., Song,H. R., ...
Several genes are known to regulate circadian rhythms in Arabidopsis, but the identity of the central oscillator has not been established. LHY and CCA1 are related MYB-like transcription factors...
Chessells, J.M., Harrison, C.J., Kempski, H., Webb, D.K., Wheatley, K., Hann, I.M., ...
The clinical features, cytogenetics and response to treatment have been examined in 180 infants (aged
Mizoguchi, T., Wheatley, K., Hanzawa, Y., Wright, L., Mizoguchi, M., Song, H. R., ...
Several genes are known to regulate circadian rhythms in Arabidopsis, but the identity of the central oscillator has not been established. LHY and CCA1 are related MYB-like transcription factors...
Kottaridis, P.D., Gale, R.E., Frew, M.E., Harrison, G., Langabeer, S.E., Belton, A.A, ...
In acute myeloid leukemia (AML), further prognostic determinants are required in addition to cytogenetics to predict patients at increased risk of relapse. Recent studies have indicated that an...
Form and function in syntax: relative clauses in Tsez. (1999)
Darnell, M., Moravcsik, E., Newmeyer, F., Noonan, M., Wheatley, K., Comrie, Bernard, ...
What (some) functionalists can learn from (some) formalists. (1999)
Darnell, M., Moravcsik, E., Newmeyer, F., Noonan, M., Wheatley, K., Croft, William
Alcohol and coronary heart disease reduction among British doctors: confounding or causality? (1997)
Aspirin use and chronic diseases
Hennekens, C H, Buring, J E, Sandercock, P A G, Gray, R, Wheatley, K, Collins, R, ...
Aspirin use and chronic diseases
Hennekens, C H, Buring, J E, Sandercock, P A G, Gray, R, Wheatley, K, Collins, R, ...
Randomised trial of prophylactic daily aspirin in British male doctors
Peto, R, Gray, R, Collins, R, Wheatley, K, Hennekens, C, Jamrozik, K, ...
A six year randomised trial was conducted among 5139 apparently healthy male doctors to see whether 500 mg aspirin daily would reduce the incidence of and mortality from stroke, myocardial...
Surgery for Parkinson's disease: lack of reliable clinical trial evidence
Stowe, R, Wheatley, K, Clarke, C, Ives, N, Hills, R, Williams, A, ...
Improved outcome of acute myeloid leukaemia in Down's syndrome
Craze, J, Harrison, G, Wheatley, K, Hann, I, Chessells, J
OBJECTIVE—To review the clinical features, treatment, and outcome of children in the UK with Down's syndrome and acute myeloid leukaemia (AML). DESIGN—A retrospective study of 59 children with...
Mortality in relation to smoking: 40 years' observations on male British doctors.
Doll, R., Peto, R., Wheatley, K., Gray, R., Sutherland, I.
OBJECTIVE--To assess the hazards associated with long term use of tobacco. DESIGN--Prospective study of mortality in relation to smoking habits assessed in 1951 and again from time to time...
Mortality in relation to consumption of alcohol: 13 years' observations on male British doctors.
Doll, R., Peto, R., Hall, E., Wheatley, K., Gray, R.
OBJECTIVE--To assess the risk of death associated with various patterns of alcohol consumption. DESIGN--Prospective study of mortality in relation to alcohol drinking habits in 1978, with causes of...
Randomised trial of prophylactic daily aspirin in British male doctors
Peto, R, Gray, R, Collins, R, Wheatley, K, Hennekens, C, Jamrozik, K, ...
A six year randomised trial was conducted among 5139 apparently healthy male doctors to see whether 500 mg aspirin daily would reduce the incidence of and mortality from stroke, myocardial...
Stiller, C A, Benjamin, S, Cartwright, R A, Clough, J V, Gorst, D W, Kroll, M E, ...
We report a population-based study of patterns of care and survival for people with acute leukaemia diagnosed at age 15–29 years during 1984–94 in regions of England and Wales covered by...