Cuddapah, Suresh, Jothi, Raja, Schones, Dustin E., Roh, Tae-Young, Cui, Kairong, Zhao, Keji
Insulators are DNA elements that prevent inappropriate interactions between the neighboring regions of the genome. They can be functionally classified as either enhancer blockers or domain barriers....
Zang, Chongzhi, Schones, Dustin E., Zeng, Chen, Cui, Kairong, Zhao, Keji, Peng, Weiqun
Motivation: Chromatin states are the key to gene regulation and cell identity. Chromatin immunoprecipitation (ChIP) coupled with high-throughput sequencing (ChIP-Seq) is increasingly being used to...
Genome-wide identification of in vivo protein-DNA binding sites from ChIP-Seq data (2008)
Jothi, Raja, Cuddapah, Suresh, Barski, Artem, Cui, Kairong, Zhao, Keji
ChIP-Seq, which combines chromatin immunoprecipitation (ChIP) with ultra high-throughput massively parallel sequencing, is increasingly being used for mapping protein–DNA interactions in-vivo on a...
Yan, Zhijiang, Cui, Kairong, Murray, Darryl M., Ling, Chen, Xue, Yutong, Gerstein, Amy, ...
PBAF and BAF are two chromatin-remodeling complexes of the SWI/SNF family essential for mammalian transcription and development. Although these complexes share eight identical subunits, only PBAF can...
Yan, Zhijiang, Cui, Kairong, Murray, Darryl M., Ling, Chen, Xue, Yutong, Gerstein, Amy, ...
PBAF and BAF are two chromatin-remodeling complexes of the SWI/SNF family essential for mammalian transcription and development. Although these complexes share eight identical subunits, only PBAF can...
Yan, Zhijiang, Cui, Kairong, Murray, Darryl M., Ling, Chen, Xue, Yutong, Gerstein, Amy, ...
PBAF and BAF are two chromatin-remodeling complexes of the SWI/SNF family essential for mammalian transcription and development. Although these complexes share eight identical subunits, only PBAF can...
BRG1 Controls the Activity of the Retinoblastoma Protein via Regulation of p21CIP1/WAF1/SDI
Kang, Hyeog, Cui, Kairong, Zhao, Keji
The ubiquitous mammalian chromatin-remodeling SWI/SNF-like BAF complexes play critical roles in tumorigenesis. It was suggested that the direct interaction of BRG1 with the retinoblastoma protein pRB...
The Chromatin-Remodeling BAF Complex Mediates Cellular Antiviral Activities by Promoter Priming
Cui, Kairong, Tailor, Prafullakumar, Liu, Hong, Chen, Xin, Ozato, Keiko, Zhao, Keji
The elicitation of cellular antiviral activities is dependent on the rapid transcriptional activation of interferon (IFN) target genes. It is not clear how the interferon target promoters, which are...
Yan, Zhijiang, Cui, Kairong, Murray, Darryl M., Ling, Chen, Xue, Yutong, Gerstein, Amy, ...
PBAF and BAF are two chromatin-remodeling complexes of the SWI/SNF family essential for mammalian transcription and development. Although these complexes share eight identical subunits, only PBAF can...
BRG1 Controls the Activity of the Retinoblastoma Protein via Regulation of p21CIP1/WAF1/SDI
Kang, Hyeog, Cui, Kairong, Zhao, Keji
The ubiquitous mammalian chromatin-remodeling SWI/SNF-like BAF complexes play critical roles in tumorigenesis. It was suggested that the direct interaction of BRG1 with the retinoblastoma protein pRB...
The Chromatin-Remodeling BAF Complex Mediates Cellular Antiviral Activities by Promoter Priming
Cui, Kairong, Tailor, Prafullakumar, Liu, Hong, Chen, Xin, Ozato, Keiko, Zhao, Keji
The elicitation of cellular antiviral activities is dependent on the rapid transcriptional activation of interferon (IFN) target genes. It is not clear how the interferon target promoters, which are...
Yan, Zhijiang, Cui, Kairong, Murray, Darryl M., Ling, Chen, Xue, Yutong, Gerstein, Amy, ...
PBAF and BAF are two chromatin-remodeling complexes of the SWI/SNF family essential for mammalian transcription and development. Although these complexes share eight identical subunits, only PBAF can...
The genomic landscape of histone modifications in human T cells
Roh, Tae-Young, Cuddapah, Suresh, Cui, Kairong, Zhao, Keji
To understand the molecular basis that supports the dynamic gene expression programs unique to T cells, we investigated the genomic landscape of activating histone modifications, including histone H3...
Genome-wide identification of in vivo protein–DNA binding sites from ChIP-Seq data
Jothi, Raja, Cuddapah, Suresh, Barski, Artem, Cui, Kairong, Zhao, Keji
ChIP-Seq, which combines chromatin immunoprecipitation (ChIP) with ultra high-throughput massively parallel sequencing, is increasingly being used for mapping protein–DNA interactions in-vivo on a...
Jani, Anant, Wan, Mimi, Zhang, Jianmin, Cui, Kairong, Wu, Jie, Preston-Hurlburt, Paula, ...
We have developed a general strategy for creating littermates bearing either a tissue-specific point mutation or deletion in any target gene, and used the method to dissect the roles of Brg, the...
Cuddapah, Suresh, Jothi, Raja, Schones, Dustin E., Roh, Tae-Young, Cui, Kairong, Zhao, Keji
Insulators are DNA elements that prevent inappropriate interactions between the neighboring regions of the genome. They can be functionally classified as either enhancer blockers or domain barriers....
Kallin, Eric M., Cao, Ru, Jothi, Raja, Xia, Kai, Cui, Kairong, Zhao, Keji, ...
Polycomb group (PcG) proteins control organism development by regulating the expression of developmental genes. Transcriptional regulation by PcG proteins is achieved, at least partly, through the...
Ho, Lena, Jothi, Raja, Ronan, Jehnna L., Cui, Kairong, Zhao, Keji, Crabtree, Gerald R.
Distinctive SWI/SNF-like ATP-dependent chromatin remodeling esBAF complexes are indispensable for the maintenance and pluripotency of mouse embryonic stem (ES) cells [Ho L, et al. (2009) Proc Natl...
Zhu, Jinfang, Davidson, Todd S., Wei, Gang, Jankovic, Dragana, Cui, Kairong, Schones, Dustin E., ...
Growth factor independent 1 (Gfi-1), a transcriptional repressor, is transiently induced during T cell activation. Interleukin (IL) 4 further induces Gfi-1, resulting in optimal Th2 cell expansion....