Kara Hoar

MLN8054, a Small-Molecule Inhibitor of Aurora A, Causes Spindle Pole and Chromosome Congression Defects Leading to Aneuploidy▿ †

Hoar, Kara, Chakravarty, Arijit, Rabino, Claudia, Wysong, Deborah, Bowman, Douglas, Roy, Natalie, ...

Aurora A kinase plays an essential role in the proper assembly and function of the mitotic spindle, as its perturbation causes defects in centrosome separation, spindle pole organization, and...