Kara M. Hoar

Melanoma inhibitor of apoptosis protein (ML-IAP) is a target for immune-mediated tumor destruction

Schmollinger, Jan C., Vonderheide, Robert H., Hoar, Kara M., Maecker, Britta, Schultze, Joachim L., Hodi, F. Stephen, ...

The identification of antigens associated with tumor destruction is a major goal of cancer immunology. Vaccination with irradiated tumor cells engineered to secrete granulocyte–macrophage colony...

Melanoma inhibitor of apoptosis protein (ML-IAP) is a target for immune-mediated tumor destruction

Schmollinger, Jan C., Vonderheide, Robert H., Hoar, Kara M., Maecker, Britta, Schultze, Joachim L., Hodi, F. Stephen, ...

The identification of antigens associated with tumor destruction is a major goal of cancer immunology. Vaccination with irradiated tumor cells engineered to secrete granulocyte–macrophage colony...

Antitumor activity of MLN8054, an orally active small-molecule inhibitor of Aurora A kinase

Manfredi, Mark G., Ecsedy, Jeffrey A., Meetze, Kristan A., Balani, Suresh K., Burenkova, Olga, Chen, Wei, ...

Increased Aurora A expression occurs in a variety of human cancers and induces chromosomal abnormalities during mitosis associated with tumor initiation and progression. MLN8054 is a selective...