Petersen, Andreas M, Nielsen, Eva M, Litrup, Eva, Brynskov, Jørn, Mirsepasi, Hengameh, Krogfelt, Karen A
Abstract Background Escherichia coli have been found in increased numbers in tissues from patients with Inflammatory Bowel Disease (IBD) and adherent-invasive E. coli have been found in resected...
Host-pathogen interactions in campylobacter infections: the host perspective (2008)
Janssen, Riny, Krogfelt, Karen A., Cawthraw, Shaun A., Pelt, Wilfrid Van, Wagenaar, J.A., Owen, Robert J.
Campylobacter is a major cause of acute bacterial diarrhea in humans worldwide (3). The incidence of human campylobacteriosis increased exponentially during the last decade of the 20th century (183),...
Schjørring, Susanne, Struve, Carsten, Krogfelt, Karen A.
Objectives and methods Klebsiella pneumoniae is a nosocomial pathogen and is considered the most common Gram-negative bacterium that exhibits multiple antimicrobial resistances. In this study, the...
Capsule and fimbria interaction in Klebsiella pneumoniae (2005)
Schembri, Mark A., Blom, Jens, Krogfelt, Karen A., Klemm, Per
The capsular polysaccharide and type I fimbriae are two of the major surface-located virulence properties associated with the pathogenesis of Klebsiella pneumoniae. The capsule is an elaborate...
Capsule and fimbria interaction in Klebsiella pneumoniae (2005)
Schembri, Mark A., Blom, Jens, Krogfelt, Karen A., Klemm, Per
The capsular polysaccharide and type I fimbriae are two of the major surface-located virulence properties associated with the pathogenesis of Klebsiella pneumoniae. The capsule is an elaborate...
Krogfelt, Karen A., Utley, Maryjane, Krivan, Howard C., Laux, David C., Cohen, Paul S.
Pseudomonas aeruginosa PAO1 became considerably more sensitive to the action of ampicillin when grown in the presence of certain phospholipids. Only phospholipids capable of forming lipid bilayers or...
Pathogenic adaptation of Escherichia coli by natural variation of the FimH adhesin
Sokurenko, Evgeni V., Chesnokova, Veronika, Dykhuizen, Daniel E., Ofek, Itzhak, Wu, Xue-Ru, Krogfelt, Karen A., ...
Conventional wisdom regarding mechanisms of bacterial pathogenesis holds that pathogens arise by external acquisition of distinct virulence factors, whereas determinants shared by pathogens and...
Hvidberg, Hanne, Struve, Carsten, Krogfelt, Karen A., Christensen, Nils, Rasmussen, Søren N., Frimodt-Møller, Niels
A model of ascending unobstructed urinary tract infection (UTI) in mice was developed to study the significance of the antibiotic concentration in urine, serum, and kidney tissue for efficacy of...
Riedel, Kathrin, Ohnesorg, Thomas, Krogfelt, Karen A., Hansen, Thomas S., Omori, Kenji, Givskov, Michael, ...
The analysis of Serratia liquefaciens MG1 ′luxAB insertion mutants that are responsive to N-butanoyl-l-homoserine lactone revealed that expression of lipB is controlled by the swr quorum-sensing...
Krogfelt, Karen A., Hjulgaard, Marianne, Sørensen, Kristine, Cohen, Paul S., Givskov, Michael
The ability of Escherichia coli to survive stress during growth in different environments is, in large part, dependent on rpoS and the genes that comprise the rpoS regulon. E. coli BJ4 and an...
Allen, James H., Utley, Maryjane, Van Den Bosch, Han, Nuijten, Piet, Witvliet, Maarten, McCormick, Beth A., ...
A minitransposon mutant of Salmonella enterica serovar Typhimurium SR-11, SR-11 Fad−, is unable to utilize gluconeogenic substrates as carbon sources and is avirulent and immunogenic when...
Rang, Camilla U., Licht, Tine Rask, Midtvedt, Tore, Conway, Patricia L., Chao, Lin, Krogfelt, Karen A., ...
The growth physiology of Escherichia coli during colonization of the intestinal tract was studied with four animal models: the streptomycin-treated mouse carrying a reduced microflora, the...
Møller, Annette K., Leatham, Mary P., Conway, Tyrrell, Nuijten, Piet J. M., Krogfelt, Karen A., ...
The ability of E. coli strains to colonize the mouse large intestine has been correlated with their ability to grow in cecal and colonic mucus. In the present study, an E. coli MG1655 strain was...
Capsule and Fimbria Interaction in Klebsiella pneumoniae
Schembri, Mark A., Blom, Jens, Krogfelt, Karen A., Klemm, Per
The capsular polysaccharide and type 1 fimbriae are two of the major surface-located virulence properties associated with the pathogenesis of Klebsiella pneumoniae. The capsule is an elaborate...
Leatham, Mary P., Stevenson, Sarah J., Gauger, Eric J., Krogfelt, Karen A., Lins, Jeremy J., Haddock, Traci L., ...
d-Gluconate which is primarily catabolized via the Entner-Doudoroff (ED) pathway, has been implicated as being important for colonization of the streptomycin-treated mouse large intestine by...
Reisner, Andreas, Krogfelt, Karen A., Klein, Bjarke M., Zechner, Ellen L., Molin, Søren
Our understanding of Escherichia coli biofilm formation in vitro is based on studies of laboratory K-12 strains grown in standard media. However, pathogenic E. coli isolates differ substantially in...
Pathogenic adaptation of Escherichia coli by natural variation of the FimH adhesin
Sokurenko, Evgeni V., Chesnokova, Veronika, Dykhuizen, Daniel E., Ofek, Itzhak, Wu, Xue-Ru, Krogfelt, Karen A., ...
Conventional wisdom regarding mechanisms of bacterial pathogenesis holds that pathogens arise by external acquisition of distinct virulence factors, whereas determinants shared by pathogens and...
Hvidberg, Hanne, Struve, Carsten, Krogfelt, Karen A., Christensen, Nils, Rasmussen, Søren N., Frimodt-Møller, Niels
A model of ascending unobstructed urinary tract infection (UTI) in mice was developed to study the significance of the antibiotic concentration in urine, serum, and kidney tissue for efficacy of...
Riedel, Kathrin, Ohnesorg, Thomas, Krogfelt, Karen A., Hansen, Thomas S., Omori, Kenji, Givskov, Michael, ...
The analysis of Serratia liquefaciens MG1 ′luxAB insertion mutants that are responsive to N-butanoyl-l-homoserine lactone revealed that expression of lipB is controlled by the swr quorum-sensing...
Krogfelt, Karen A., Hjulgaard, Marianne, Sørensen, Kristine, Cohen, Paul S., Givskov, Michael
The ability of Escherichia coli to survive stress during growth in different environments is, in large part, dependent on rpoS and the genes that comprise the rpoS regulon. E. coli BJ4 and an...
Allen, James H., Utley, Maryjane, Van Den Bosch, Han, Nuijten, Piet, Witvliet, Maarten, McCormick, Beth A., ...
A minitransposon mutant of Salmonella enterica serovar Typhimurium SR-11, SR-11 Fad−, is unable to utilize gluconeogenic substrates as carbon sources and is avirulent and immunogenic when...
Rang, Camilla U., Licht, Tine Rask, Midtvedt, Tore, Conway, Patricia L., Chao, Lin, Krogfelt, Karen A., ...
The growth physiology of Escherichia coli during colonization of the intestinal tract was studied with four animal models: the streptomycin-treated mouse carrying a reduced microflora, the...
Møller, Annette K., Leatham, Mary P., Conway, Tyrrell, Nuijten, Piet J. M., Krogfelt, Karen A., ...
The ability of E. coli strains to colonize the mouse large intestine has been correlated with their ability to grow in cecal and colonic mucus. In the present study, an E. coli MG1655 strain was...
Capsule and Fimbria Interaction in Klebsiella pneumoniae
Schembri, Mark A., Blom, Jens, Krogfelt, Karen A., Klemm, Per
The capsular polysaccharide and type 1 fimbriae are two of the major surface-located virulence properties associated with the pathogenesis of Klebsiella pneumoniae. The capsule is an elaborate...
Leatham, Mary P., Stevenson, Sarah J., Gauger, Eric J., Krogfelt, Karen A., Lins, Jeremy J., Haddock, Traci L., ...
d-Gluconate which is primarily catabolized via the Entner-Doudoroff (ED) pathway, has been implicated as being important for colonization of the streptomycin-treated mouse large intestine by...
Reisner, Andreas, Krogfelt, Karen A., Klein, Bjarke M., Zechner, Ellen L., Molin, Søren
Our understanding of Escherichia coli biofilm formation in vitro is based on studies of laboratory K-12 strains grown in standard media. However, pathogenic E. coli isolates differ substantially in...
Strid, Mette A., Dalby, Tine, Mølbak, Kåre, Krogfelt, Karen A.
Two indirect enzyme-linked immunosorbent assays (ELISAs) were employed to measure levels of immunoglobulin G (IgG), IgM, and IgA antibodies against Salmonella in sera from 303 Danish patients...
Fouts, Derrick E., Tyler, Heather L., DeBoy, Robert T., Daugherty, Sean, Ren, Qinghu, Badger, Jonathan H., ...
We report here the sequencing and analysis of the genome of the nitrogen-fixing endophyte, Klebsiella pneumoniae 342. Although K. pneumoniae 342 is a member of the enteric bacteria, it serves as a...
Glycogen and Maltose Utilization by Escherichia coli O157:H7 in the Mouse Intestine▿
Jones, Shari A., Jorgensen, Mathias, Chowdhury, Fatema Z., Rodgers, Rosalie, Hartline, James, Leatham, Mary P., ...
Mutant screens and transcriptome studies led us to consider whether the metabolism of glucose polymers, i.e., maltose, maltodextrin, and glycogen, is important for Escherichia coli colonization of...
New Adhesin of Enteroaggregative Escherichia coli Related to the Afa/Dr/AAF Family▿
Boisen, Nadia, Struve, Carsten, Scheutz, Flemming, Krogfelt, Karen A., Nataro, James P.
Enteroaggregative Escherichia coli (EAEC) is an important cause of diarrhea worldwide. We analyzed 17 Danish EAEC strains, isolated in the course of a case control study, for phenotypic and genotypic...
Harboe, Zitta B., Thomsen, Reimar W., Riis, Anders, Valentiner-Branth, Palle, Christensen, Jens Jørgen, Lambertsen, Lotte, ...
Analyzing population-based data collected over 30 years in more than 18,000 patients with invasive pneumococcal infection, Zitta Harboe and colleagues find specific pneumococcal serotypes to be...
Host-Pathogen Interactions in Campylobacter Infections: the Host Perspective
Janssen, Riny, Krogfelt, Karen A., Cawthraw, Shaun A., Van Pelt, Wilfrid, Wagenaar, Jaap A., Owen, Robert J.
Campylobacter is a major cause of acute bacterial diarrhea in humans worldwide. This study was aimed at summarizing the current understanding of host mechanisms involved in the defense against...