Karen Duca

IEEE TRANSACTIONS VISUALIZATION AND COMPUTER GRAPHICS An Insight-based Methodology for Evaluating (2008)

Bioinformatics Visualizations, Purvi Saraiya, Chris North, Karen Duca

Abstract — High-throughput experiments such as gene expression microarrays in the life sciences result in very large datasets. In response, a wide variety of visualization tools have been created...

BIOINFORMATICS ORIGINAL PAPER doi:10.1093/bioinformatics/btm044 Systems biology Simulating Epstein-Barr virus infection with C-ImmSim (2008)

Karen Duca, Abdul Jarrah, Reinhard Laubenbacher, Donna Hochberg, David Thorley-lawson

Motivation: Epstein-Barr virus (EBV) infects greater than 90 % of humans benignly for life but can be associated with tumors. It is a uniquely human pathogen that is amenable to quantitative...

Simulating Epstein-Barr virus infection with C-ImmSim (2007)

Castiglione, Filippo, Duca, Karen, Jarrah, Abdul, Laubenbacher, Reinhard, Hochberg, Donna, Thorley-Lawson, David

Motivation: Epstein-Barr virus (EBV) infects greater than 90% of humans benignly for life but can be associated with tumors. It is a uniquely human pathogen that is amenable to quantitative analysis;...

An insight-based methodology for evaluating bioinformatics visualizations (2005)

Purvi Saraiya, Chris North, Karen Duca

Abstract—High-throughput experiments, such as gene expression microarrays in the life sciences, result in very large data sets. In response, a wide variety of visualization tools have been created...

An evaluation of microarray visualization tools for biological insight (2004)

Purvi Saraiya, Chris North, Karen Duca

High-throughput experiments such as gene expression microarrays in the life sciences result in very large datasets. In response, a wide variety of visualization tools have been created to facilitate...

Visualization of Biological Pathways: An ethnographic study and Systems Evaluation (2004)

Purvi Saraiya, Chris North, Karen Duca

Life scientists use pathway diagrams to represent complex biochemical interactions at the molecular level. Although several visualization software systems have been developed to assist them in...