Karen E. Nelson

Microbiology (1999), 145, 2625–2634 Printed in Great Britain REVIEW ARTICLE Overview (2009)

Lionel Frangeul, Karen E. Nelson, Carmen Buchrieser, Antoine Danchin, Frank Kunst

The knowledge of an entire genome sequence not only provides a wealth of data, but also specific information that can not be obtained by other approaches. Only after...

Secrets of Soil Survival Revealed by the Genome Sequence of Arthrobacter aurescens TC1 (2006)

Emmanuel F. Mongodin, Nir Shapir, Sean C. Daugherty, Robert T. DeBoy, Joanne B. Emerson, Alla Shvartzbeyn, ...

Arthrobacter sp. strains are among the most frequently isolated, indigenous, aerobic bacterial genera found in soils. Member of the genus are metabolically and ecologically diverse and have the...

A Guild of 45 CRISPR-Associated (Cas) Protein Families and Multiple CRISPR/Cas Subtypes Exist in Prokaryotic Genomes (2005)

Daniel H. Haft, Jeremy Selengut, Emmanuel F. Mongodin, Karen E. Nelson

Clustered regularly interspaced short palindromic repeats (CRISPRs) are a family of DNA direct repeats found in many prokaryotic genomes. Repeats of 21–37 bp typically show weak dyad symmetry and...

A guild of forty-five CRISPR-associated (Cas) protein families and multiple CRISPR/Cas subtypes exist in prokaryotic genomes (2005)

Daniel Henry Haft, Jeremy Selengut, Emmanuel F Mongodin, Karen E Nelson

Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) is a family of DNA direct repeats found in many prokaryotic genomes. Repeats of 21-37 bp typically show weak dyad symmetry and are...

Major Structural Differences and Novel Potential Virulence Mechanisms from the Genomes of Multiple Campylobacter Species (2005)

Derrick E. Fouts, Emmanuel F. Mongodin, Robert E. Mandrell, William G. Miller, David A. Rasko, Jacques Ravel, ...

Sequencing and comparative genome analysis of four strains of Campylobacter including C. lari RM2100, C. upsaliensis RM3195, and C. coli RM2228 has revealed major structural differences that are...

Genomic Insights into Methanotrophy: The Complete Genome Sequence of Methylococcus capsulatus (Bath) (2004)

Naomi Ward, Øivind Larsen, James Sakwa, Live Bruseth, Hoda Khouri, A. Scott Durkin, ...

Methanotrophs are ubiquitous bacteria that can use the greenhouse gas methane as a sole carbon and energy source for growth, thus playing major roles in global carbon cycles, and in particular,...

Genomic Insights into Methanotrophy: The Complete Genome Sequence of Methylococcus capsulatus (Bath) (2004)

Ward, Naomi, Larsen, Øivind, Sakwa, James, Bruseth, Live, Khouri, Hoda, Durkin, A. Scott, ...

Methanotrophs are ubiquitous bacteria that can use the greenhouse gas methane as a sole carbon and energy source for growth, thus playing major roles in global carbon cycles, and in particular,...

Genomic Insights into Methanotrophy : the Complete Genome Sequence of Methylococcus capsulatus (Bath) (2004)

Ward, Naomi, Larsen, Øivind, Sakwa, James, Bruseth, Live, Khouri, Hoda, Durkin, A. Scott, ...

Methanotrophs are ubiquitous bacteria that can use the greenhouse gas methane as a sole carbon and energy source for growth, thus playing major roles in global carbon cycles, and in particular,...

Phylogenomics of the reproductive parasite Wolbachia pipientis wMel: A streamlined genome overrun by mobile genetic elements (2004)

Wu, Martin, Sun, Ling V., Vamathevan, Jessica, Riegler, Markus, Deboy, Robert, Brownlie, Jeremy C., ...

The complete sequence of the 1,267,782 bp genome of Wolbachia pipientis wMel, an obligate intracellular bacteria of Drosophila melanogaster, has been determined. Wolbachia, which are found in a...

Phylogenomics of the Reproductive Parasite Wolbachia pipientis wMel: A Streamlined Genome Overrun by Mobile Genetic Elements (2004)

Wu, Martin, Sun, Ling V., Vamathevan, Jessica, Riegler, Markus, Deboy, Robert, Brownlie, Jeremy C., ...

The complete sequence of the 1,267,782 bp genome of Wolbachia pipientis wMel, an obligate intracellular bacteria of Drosophila melanogaster, has been determined. Wolbachia, which are found in a...

Phylogenomics of the reproductive parasite Wolbachia pipientis wMel: a streamlined genome overrun with mobile genetic elements (2004)

Wu, Martin, Sun, Ling V., Vamathevan, Jessica, Riegler, Markus, Deboy, Robert, Brownlie, Jeremy C., ...

The complete sequence of the 1,267,782 bp genome of Wolbachia pipientis wMel, an obligate intracellular bacteria of Drosophila melanogaster, has been determined. Wolbachia, which are found in a...

Whole genome comparisons of serotype 4b and 1/2a strains of the food-borne pathogen Listeria monocytogenes reveal new insights into the core genome components of this species (2004)

Nelson, Karen E., Fouts, Derrick E., Mongodin, Emmanuel F., Ravel, Jacques, DeBoy, Robert T., Kolonay, James F., ...

The genomes of three strains of Listeria monocytogenes that have been associated with food‐borne illness in the USA were subjected to whole genome comparative analysis. A total of 51, 97 and 69...

General method of rapid Smith/Birnstiel mapping adds for gap closure in shotgun microbial genome sequencing projects: application to Pseudomonas putida KT2440 (2001)

Weinel, Christian, Tümmler, Burkhard, Hilbert, Helmut, Nelson, Karen E., Kiewitz, Claudia

A physical mapping strategy has been developed to verify and accelerate the assembly and gap closure phase of a microbial genome shotgun-sequencing project. The protocol was worked out during the...

Structural analysis of DNA sequence: evidence for lateral gene transfer in Thermotoga maritima (2000)

Worning, Peder, Jensen, Lars J., Nelson, Karen E., Brunak, Søren, Ussery, David W.

The recently published complete DNA sequence of the bacterium Thermotoga maritima provides evidence, based on protein sequence conservation, for lateral gene transfer between Archaea and Bacteria. We...

Population Diversity and Dynamics of Streptococcus mitis, Streptococcus oralis, and Streptococcus infantis in the Upper Respiratory Tracts of Adults, Determined by a Nonculture Strategy▿

Bek-Thomsen, Malene, Tettelin, Hervé, Hance, Ioana, Nelson, Karen E., Kilian, Mogens

We reinvestigated the clonal diversity and dynamics of Streptococcus mitis and two other abundant members of the commensal microbiota of the upper respiratory tract, Streptococcus oralis and...

Insights into Plant Cell Wall Degradation from the Genome Sequence of the Soil Bacterium Cellvibrio japonicus▿ †

DeBoy, Robert T., Mongodin, Emmanuel F., Fouts, Derrick E., Tailford, Louise E., Khouri, Hoda, Emerson, Joanne B., ...

The plant cell wall, which consists of a highly complex array of interconnecting polysaccharides, is the most abundant source of organic carbon in the biosphere. Microorganisms that degrade the plant...

Extensive Genome Rearrangements and Multiple Horizontal Gene Transfers in a Population of Pyrococcus Isolates from Vulcano Island, Italy▿ †

White, James R., Escobar-Paramo, Patricia, Mongodin, Emmanuel F., Nelson, Karen E., DiRuggiero, Jocelyne

The extent of chromosome rearrangements in Pyrococcus isolates from marine hydrothermal vents in Vulcano Island, Italy, was evaluated by high-throughput genomic methods. The results illustrate the...

Hydrogenomics of the Extremely Thermophilic Bacterium Caldicellulosiruptor saccharolyticus▿ †

Verhaart, Marcel R. A., VanFossen, Amy L., Willquist, Karin, Lewis, Derrick L., Nichols, Jason D., ...

Caldicellulosiruptor saccharolyticus is an extremely thermophilic, gram-positive anaerobe which ferments cellulose-, hemicellulose- and pectin-containing biomass to acetate, CO2, and hydrogen. Its...

Gene-centric metagenomics of the fiber-adherent bovine rumen microbiome reveals forage specific glycoside hydrolases

Brulc, Jennifer M., Antonopoulos, Dionysios A., Berg Miller, Margret E., Wilson, Melissa K., Yannarell, Anthony C., Dinsdale, Elizabeth A., ...

The complex microbiome of the rumen functions as an effective system for the conversion of plant cell wall biomass to microbial protein, short chain fatty acids, and gases. As such, it provides a...

Three Genomes from the Phylum Acidobacteria Provide Insight into the Lifestyles of These Microorganisms in Soils▿ †

Ward, Naomi L., Challacombe, Jean F., Janssen, Peter H., Henrissat, Bernard, Coutinho, Pedro M., Wu, Martin, ...

The complete genomes of three strains from the phylum Acidobacteria were compared. Phylogenetic analysis placed them as a unique phylum. They share genomic traits with members of the Proteobacteria,...

On the chimeric nature, thermophilic origin, and phylogenetic placement of the Thermotogales

Zhaxybayeva, Olga, Swithers, Kristen S., Lapierre, Pascal, Fournier, Gregory P., Bickhart, Derek M., DeBoy, Robert T., ...

Since publication of the first Thermotogales genome, Thermotoga maritima strain MSB8, single- and multi-gene analyses have disagreed on the phylogenetic position of this order of Bacteria. Here we...