Distiller, Greg B, Little, Francesca, Barnes, Karen I
Abstract Background Gametocytes are the sexual form of the malaria parasite and the main agents of transmission. While there are several factors that influence host infectivity, the density of...
Barnes, Karen I, Chanda, Pascalina, Ab Barnabas, Gebre
Abstract Malaria is one of the most significant causes of morbidity and mortality worldwide. Every year, nearly one million deaths result from malaria infection. Malaria can be controlled in endemic...
Allen, Elizabeth N, Little, Francesca, Camba, Tunisio, Cassam, Yasmin, Raman, Jaishree, Boulle, Andrew, ...
Abstract Background An artemisinin-based combination therapy, artesunate (AS) plus sulphadoxine-pyrimethamine (SP), was compared to SP monotherapy to provide evidence of further treatment options in...
Zikusooka, Charlotte M, McIntyre, Diane, Barnes, Karen I
Abstract Background Within the context of increasing antimalarial costs and or decreasing malaria transmission, the importance of limiting antimalarial treatment to only those confirmed as having...
Barnes, Karen I., Little, Francesca, Mabuza, Aaron, Mngomezulu, Nicros, Govere, John, Durrheim, David, ...
Background: Although malaria treatment aims primarily to eliminate the asexual blood stages that cause illness, reducing the carriage of gametocytes is critical for limiting malaria transmission and...
Barnes, Karen I., Little, Francesca, Mabuza, Aaron, Mngomezulu, Nicros, Govere, John, Durrheim, David, ...
Background: Although malaria treatment aims primarily to eliminate the asexual blood stages that cause illness, reducing the carriage of gametocytes is critical for limiting malaria transmission and...
Mehta, Ushma, Durrheim, David N., Blockman, Marc, Kredo, Tamara, Gounden, Ronald, Barnes, Karen I.
Aims: To describe issues noted and recommendations made by community pharmacists during reviews of medicines and lifestyle relating to coronary heart disease (CHD), and to identify and quantify...
Barnes, Karen I., Little, Francesca, Mabuza, Aaron, Mngomezulu, Nicros, Govere, John, Durrheim, David, ...
Background: Although malaria treatment aims primarily to eliminate the asexual blood stages that cause illness, reducing the carriage of gametocytes is critical for limiting malaria transmission and...
Mehta, Ushma, Durrheim, David N., Blockman, Marc, Kredo, Tamara, Gounden, Ronald, Barnes, Karen I.
Aims: To describe issues noted and recommendations made by community pharmacists during reviews of medicines and lifestyle relating to coronary heart disease (CHD), and to identify and quantify...
The rationale and plan for creating a World Antimalarial Resistance Network (WARN) (2007)
Sibley, Carol, Barnes, Karen I, Plowe, Christopher V
Abstract Drug resistant malaria was a major factor contributing to the failure of a worldwide campaign to eradicate malaria in the last century, and now threatens the large investment being made by...
World Antimalarial Resistance Network I: Clinical efficacy of antimalarial drugs (2007)
Price, Ric N, Dorsey, Grant, Ashley, Elizabeth A, Barnes, Karen I, Baird, J Kevin, D'Alessandro, Umberto, ...
Abstract The proliferation of antimalarial drug trials in the last ten years provides the opportunity to launch a concerted global surveillance effort to monitor antimalarial drug efficacy. The...
World Antimalarial Resistance Network (WARN) IV: Clinical pharmacology (2007)
Barnes, Karen I, Lindegardh, Niklas, Ogundahunsi, Olumide, Olliaro, Piero, Plowe, Christopher V, Randrianarivelojosia, Milijaona, ...
Abstract A World Antimalarial Resistance Network (WARN) database has the potential to improve the treatment of malaria, through informing current drug selection and use and providing a prompt warning...
Sharpe, B.L., Kleinschmidt, Immo, Streat, Elisabeth, Maharaj, Rajendra, Barnes, Karen I., Durrheim, David N., ...
The Lubombo Spatial Development Initiative is a joint development program between the governments of Mozambique, Swaziland, and South Africa, which includes malaria control as a core component of the...
Sharpe, B.L., Kleinschmidt, Immo, Streat, Elisabeth, Maharaj, Rajendra, Barnes, Karen I., Durrheim, David N., ...
The Lubombo Spatial Development Initiative is a joint development program between the governments of Mozambique, Swaziland, and South Africa, which includes malaria control as a core component of the...
Sharpe, B.L., Kleinschmidt, Immo, Streat, Elisabeth, Maharaj, Rajendra, Barnes, Karen I., Durrheim, David N., ...
The Lubombo Spatial Development Initiative is a joint development program between the governments of Mozambique, Swaziland, and South Africa, which includes malaria control as a core component of the...
Sulfadoxine-pyrimethamine pharmacokinetics in malaria: Pediatric dosing implications* (2006)
Karen I. Barnes, Francesca Little, Peter J. Smith, Alicia Evans, William M. Watkins, Nicholas J. White
Julie A. Simpson, Tsiri Agbenyega, Karen I. Barnes, Gianni Di Perri, Peter Folb, Melba Gomes, ...
BackgroundIntra-rectal artesunate has been developed as a potentially life-saving treatment of severe malaria in rural village settings where administration of parenteral antimalarial drugs is not...
Karen I. Barnes, David N. Durrheim, Francesca Little, Amanda Jackson, Ushma Mehta, Elizabeth Allen, ...
In KwaZulu-Natal strengthening of vector control and a change in antimalarial treatment policy to use of artemether-lumefantrine has been associated with a decrease in malaria cases, admissions, and...
Karen I. Barnes, David N. Durrheim, Francesca Little, Amanda Jackson, Ushma Mehta, Elizabeth Allen, ...
Background Between 1995 and 2000, KwaZulu–Natal province, South Africa, experienced a marked increase in Plasmodium falciparum malaria, fuelled by pyrethroid and sulfadoxine-pyrimethamine...
Dzinjalamala, Fraction K., Macheso, Allan, Kublin, James G., Taylor, Terrie E., Barnes, Karen I., Molyneux, Malcolm E., ...
Sulfadoxine-pyrimethamine (SP) has been widely used in recent years to treat acute uncomplicated Plasmodium falciparum malaria. Risk factors for SP therapeutic failure include young age,...
Malenga, Grace, Palmer, Ayo, Staedke, Sarah, Kazadi, Walter, Mutabingwa, Theonest, Ansah, Evelyn, ...
Barnes, Karen I, Durrheim, David N, Little, Francesca, Jackson, Amanda, Mehta, Ushma, Allen, Elizabeth, ...
In KwaZulu-Natal strengthening of vector control and a change in antimalarial treatment policy to use of artemether-lumefantrine has been associated with a decrease in malaria cases, admissions, and...
Simpson, Julie A, Agbenyega, Tsiri, Barnes, Karen I, Perri, Gianni Di, Folb, Peter, Gomes, Melba, ...
A study of the population pharmacokinetics of intra-rectal artesunate in patients with moderately severe falciparum malaria found the pharmacokinetic properties of dihydroartemisinin were affected...
Dzinjalamala, Fraction K., Macheso, Allan, Kublin, James G., Taylor, Terrie E., Barnes, Karen I., Molyneux, Malcolm E., ...
Sulfadoxine-pyrimethamine (SP) has been widely used in recent years to treat acute uncomplicated Plasmodium falciparum malaria. Risk factors for SP therapeutic failure include young age,...
Malenga, Grace, Palmer, Ayo, Staedke, Sarah, Kazadi, Walter, Mutabingwa, Theonest, Ansah, Evelyn, ...
Barnes, Karen I, Durrheim, David N, Little, Francesca, Jackson, Amanda, Mehta, Ushma, Allen, Elizabeth, ...
In KwaZulu-Natal strengthening of vector control and a change in antimalarial treatment policy to use of artemether-lumefantrine has been associated with a decrease in malaria cases, admissions, and...
Simpson, Julie A, Agbenyega, Tsiri, Barnes, Karen I, Perri, Gianni Di, Folb, Peter, Gomes, Melba, ...
A study of the population pharmacokinetics of intra-rectal artesunate in patients with moderately severe falciparum malaria found the pharmacokinetic properties of dihydroartemisinin were affected...
The rationale and plan for creating a World Antimalarial Resistance Network (WARN)
Sibley, Carol Hopkins, Barnes, Karen I, Plowe, Christopher V
Drug resistant malaria was a major factor contributing to the failure of a worldwide campaign to eradicate malaria in the last century, and now threatens the large investment being made by the global...
World Antimalarial Resistance Network I: Clinical efficacy of antimalarial drugs
Price, Ric N, Dorsey, Grant, Ashley, Elizabeth A, Barnes, Karen I, Baird, J Kevin, D'Alessandro, Umberto, ...
The proliferation of antimalarial drug trials in the last ten years provides the opportunity to launch a concerted global surveillance effort to monitor antimalarial drug efficacy. The diversity of...
World Antimalarial Resistance Network (WARN) IV: Clinical pharmacology
Barnes, Karen I, Lindegardh, Niklas, Ogundahunsi, Olumide, Olliaro, Piero, Plowe, Christopher V, Randrianarivelojosia, Milijaona, ...
A World Antimalarial Resistance Network (WARN) database has the potential to improve the treatment of malaria, through informing current drug selection and use and providing a prompt warning of when...
Orrell, Catherine, Little, Francesca, Smith, Peter, Folb, Peter, Taylor, Walter, Olliaro, Piero, ...
Multiple Origins and Regional Dispersal of Resistant dhps in African Plasmodium falciparum Malaria
Pearce, Richard J., Pota, Hirva, Evehe, Marie-Solange B., Bâ, El-Hadj, Mombo-Ngoma, Ghyslain, Malisa, Allen L., ...
Cally Roper and colleagues analyze the distribution of sulfadoxine resistance mutations and flanking microsatellite loci to trace the emergence and dispersal of drug-resistant Plasmodium falciparum...
Allen, Elizabeth N, Little, Francesca, Camba, Tunisio, Cassam, Yasmin, Raman, Jaishree, Boulle, Andrew, ...
Barnes, Karen I, Chanda, Pascalina, Ab Barnabas, Gebre
Malaria is one of the most significant causes of morbidity and mortality worldwide. Every year, nearly one million deaths result from malaria infection. Malaria can be controlled in endemic countries...