Stephen J. Allen, Angela Allen, Michael P. Alpers, David J. Weatherall, Karen P. Day
BackgroundThe heritable haemoglobinopathy α+-thalassaemia is caused by the reduced synthesis of α-globin chains that form part of normal adult haemoglobin (Hb). Individuals homozygous for...
Host erythrocyte polymorphisms and exposure to Plasmodium falciparumin Papua New Guinea (2008)
Fowkes, Freya JI, Michon, Pascal, Pilling, Lynn, Ripley, Ruth M, Tavul, Livingstone, Imrie, Heather J, ...
Abstract Background The protection afforded by human erythrocyte polymorphisms against the malaria parasite, Plasmodium falciparum , has been proposed to be due to reduced ability of the parasite to...
Hume, Jennifer CC, Tunnicliff, Mark, Ranford-Cartwright, Lisa C, Day, Karen P
Abstract Background The susceptibility of anopheline mosquito species to Plasmodium infection is known to be variable with some mosquitoes more permissive to infection than others. Little work,...
Correction: Population Genomics of the Immune Evasion (var) Genes of Plasmodium falciparum (2007)
Alyssa E. Barry, Aleksandra Leliwa-Sytek, Livingston Tavul, Heather Imrie, Florence Migot-Nabias, Stuart M. Brown, ...
Population Genomics of the Immune Evasion (var) Genes of Plasmodium falciparum (2007)
Alyssa E. Barry, Aleksandra Leliwa-Sytek, Livingston Tavul, Heather Imrie, Florence Migot-Nabias, Stuart M. Brown, ...
Var genes encode the major surface antigen (PfEMP1) of the blood stages of the human malaria parasite Plasmodium falciparum. Differential expression of up to 60 diverse var genes in each parasite...
Association of house spraying with suppressed levels of drug resistance in Zimbabwe (2004)
Mharakurwa, Sungano, Mutambu, Susan L, Mudyiradima, Robert, Chimbadzwa, Tawanda, Chandiwana, Steven K, Day, Karen P
Abstract Background Public health strategies are needed to curb antimalarial drug resistance. Theoretical argument points to an association between malaria transmission and drug resistance although...
Association of house spraying with suppressed levels of drug resistance in Zimbabwe (2004)
Mharakurwa, Sungano, Mutambu, Susan L, Mudyiradima, Robert, Chimbadzwa, Tawanda, Chandiwana, Steven K, Day, Karen P
Background: Public health strategies are needed to curb antimalarial drug resistance. Theoretical argument points to an association between malaria transmission and drug resistance although field...
Anderson, Timothy J. C., Haubold, Bernhard, Williams, Jeff T., Estrada-Franco§, Jose G., Richardson, Lynne, Mollinedo, Rene, ...
Multilocus genotyping of microbial pathogens has revealed a range of population structures, with some bacteria showing extensive recombination and others showing almost complete clonality. The...
Virulence and transmission success of the malarial parasite Plasmodium falciparum
Hayward, Rhian E., Tiwari, Bela, Piper, Karen P., Baruch, Dror I., Day, Karen P.
Virulence of Plasmodium falciparum is associated with the expression of variant surface antigens designated PfEMP1 (P. falciparum erythrocyte membrane protein 1) that are encoded by a family of var...
Malaria Transmission and Naturally Acquired Immunity to PfEMP-1
Piper, Karen P., Hayward, Rhian E., Cox, Martin J., Day, Karen P.
Why there are so few gametocytes (the transmission stage of malaria) in the blood of humans infected with Plasmodium spp. is intriguing. This may be due either to reproductive restraint by the...
Association of house spraying with suppressed levels of drug resistance in Zimbabwe
Mharakurwa, Sungano, Mutambu, Susan L, Mudyiradima, Robert, Chimbadzwa, Tawanda, Chandiwana, Steven K, Day, Karen P
Virulence and transmission success of the malarial parasite Plasmodium falciparum
Hayward, Rhian E., Tiwari, Bela, Piper, Karen P., Baruch, Dror I., Day, Karen P.
Virulence of Plasmodium falciparum is associated with the expression of variant surface antigens designated PfEMP1 (P. falciparum erythrocyte membrane protein 1) that are encoded by a family of var...
Malaria Transmission and Naturally Acquired Immunity to PfEMP-1
Piper, Karen P., Hayward, Rhian E., Cox, Martin J., Day, Karen P.
Why there are so few gametocytes (the transmission stage of malaria) in the blood of humans infected with Plasmodium spp. is intriguing. This may be due either to reproductive restraint by the...
Association of house spraying with suppressed levels of drug resistance in Zimbabwe
Mharakurwa, Sungano, Mutambu, Susan L, Mudyiradima, Robert, Chimbadzwa, Tawanda, Chandiwana, Steven K, Day, Karen P
Population Genomics of the Immune Evasion (var) Genes of Plasmodium falciparum
Barry, Alyssa E, Leliwa-Sytek, Aleksandra, Tavul, Livingston, Imrie, Heather, Migot-Nabias, Florence, Brown, Stuart M, ...
Var genes encode the major surface antigen (PfEMP1) of the blood stages of the human malaria parasite Plasmodium falciparum. Differential expression of up to 60 diverse var genes in each parasite...
Correction: Population Genomics of the Immune Evasion (var) Genes of Plasmodium falciparum
Barry, Alyssa E, Leliwa-Sytek, Aleksandra, Tavul, Livingston, Imrie, Heather, Migot-Nabias, Florence, Brown, Stuart M, ...
Host erythrocyte polymorphisms and exposure to Plasmodium falciparum in Papua New Guinea
Fowkes, Freya JI, Michon, Pascal, Pilling, Lynn, Ripley, Ruth M, Tavul, Livingstone, Imrie, Heather J, ...
Fowkes, Freya J. I, Allen, Stephen J, Allen, Angela, Alpers, Michael P, Weatherall, David J, Day, Karen P
Karen Day and colleagues show that increased microcytic erythrocyte count may contribute substantially to the protection of α+-thalassaemia-homozygous children against severe malaria anaemia.