Karen Tan

The Use of Profits as Opposed to Conventional Forecast Evaluation Criteria to Determine the Quality of Economic Forecasts (2007)

Chow Kong Wing, Karen Tan, Lu Yi

Using profits to evaluate the quality of forecasts for the 3-month yen certificate of deposit, a profiterror relationship is detected except for the case of the professional forecasts. Professional...

Rex di Bona, (2007)

Karen Tan, David Feng, Brian Hutton

Medical imaging is becoming a standard tool for the diagnosis of diseases and disorders in patients. The usefulness of the images is dependent on the accuracy of the images to the subject. The...

Prevalence and functionality of paucimorphic and private MC4R mutations in a large, unselected European British population, scanned by meltMADGE (2007)

Alharbi, Khalid K., Spanakis, Emmanuel, Tan, Karen, Smith, Matt J., Aldahmesh, Mohammed A., O'Dell, Sandra D., ...

Identification of unknown mutations has remained laborious, expensive, and only viable for studies of selected cases. Population-based "reference ranges" of rarer sequence diversity are not...

A Sertoli cell-selective knockout of the androgen receptor causes spermatogenic arrest in meiosis (2004)

Saunders, Philippa T K, ...

Androgens control spermatogenesis, but germ cells themselves do not express a functional androgen receptor (AR). Androgen regulation is thought to be mediated by Sertoli and peritubular myoid cells,...

Serrate1-induced Notch signalling regulates the decision between immunity and tolerance made by peripheral CD4+ T cells (2000)

Hoyne, Gerard F., Le Roux, Isabelle, Corsin-Jimenez, Marta, Tan, Karen, Dunne, Jenny, Forsyth, Lynn M. G., ...

Signals derived from antigen-presenting cells (APC) influence the functional differentiation of CD4+ T cells. We report here that Serrate1 (Jagged1), a ligand for the Notch1 receptor, may...

A Sertoli cell-selective knockout of the androgen receptor causes spermatogenic arrest in meiosis

De Gendt, Karel, Swinnen, Johannes V., Saunders, Philippa T. K., Schoonjans, Luc, Dewerchin, Mieke, Devos, Ann, ...

Androgens control spermatogenesis, but germ cells themselves do not express a functional androgen receptor (AR). Androgen regulation is thought to be mediated by Sertoli and peritubular myoid cells,...

A Sertoli cell-selective knockout of the androgen receptor causes spermatogenic arrest in meiosis

De Gendt, Karel, Swinnen, Johannes V., Saunders, Philippa T. K., Schoonjans, Luc, Dewerchin, Mieke, Devos, Ann, ...

Androgens control spermatogenesis, but germ cells themselves do not express a functional androgen receptor (AR). Androgen regulation is thought to be mediated by Sertoli and peritubular myoid cells,...

Prevalence of Melanocortin-4 Receptor Deficiency in Europeans and Their Age-Dependent Penetrance in Multigenerational Pedigrees

Stutzmann, Fanny, Tan, Karen, Vatin, Vincent, Dina, Christian, Jouret, Béatrice, Tichet, Jean, ...

OBJECTIVE— Melanocortin-4 receptor (MC4R) deficiency is the most frequent genetic cause of obesity. However, there is uncertainty regarding the degree of penetrance of this condition, and the...