The CHD remodeling factor Hrp1 stimulates CENP-A loading to centromeres (2005)
Walfridsson, Julian, Bjerling, Pernilla, Thalen, Maria, Yoo, Eung-Jae, Park, Sang Dai, Ekwall, Karl
Centromeres of fission yeast are arranged with a central core DNA sequence flanked by repeated sequences. The centromere-associated histone H3 variant Cnp1 (SpCENP-A) binds exclusively to central...
Djupedal, Ingela, Portoso, Manuela, Spåhr, Henrik, Bonilla, Carolina, Gustafsson, Claes M., Allshire, Robin C., ...
Fission yeast centromeric repeats are transcribed into small interfering RNA (siRNA) precursors (pre-siRNAs), which are processed by Dicer to direct heterochromatin formation. Recently, Rpb1 and Rpb2...
Xue,Yongtao T., Haas,Stefan, Brino,Laurento, Gusnanto,Arief, Riemers,Mark, Talibi,Driss, ...
Completion of the fission yeast genome sequence has opened up possibilities for post-genomic approaches. We have constructed a DNA microarray for genome-wide gene expression analysis in fission...
Xue,Yongtao T., Haas,Stefan, Brino,Laurento, Gusnanto,Arief, Riemers,Mark, Talibi,Driss, ...
Completion of the fission yeast genome sequence has opened up possibilities for post-genomic approaches. We have constructed a DNA microarray for genome-wide gene expression analysis in fission...
Xue, Yongtao T., Haas, Stefan, Brino, Laurento, Gusnanto, Arief, Riemers, Mark, Talibi, Driss, ...
Completion of the fission yeast genome sequence has opened up possibilities for post-genomic approaches. We have constructed a DNA microarray for genome-wide gene expression analysis in fission...
Xue, Yongtao T., Haas, Stefan, Brino, Laurento, Gusnanto, Arief, Riemers, Mark, Talibi, Driss, ...
Completion of the fission yeast genome sequence has opened up possibilities for post-genomic approaches. We have constructed a DNA microarray for genome-wide gene expression analysis in fission...
Bjerling, Pernilla, Ekwall, Karl, Egel, Richard, Thon, Geneviève
The mating-type region of the fission yeast Schizosaccharomyces pombe comprises three loci: mat1, mat2-P and mat3-M. mat1 is expressed and determines the mating type of the cell. mat2-P and mat3-M...
Xue,Yongtao T., Haas,Stefan, Brino,Laurento, Gusnanto,Arief, Riemers,Mark, Talibi,Driss, ...
Completion of the fission yeast genome sequence has opened up possibilities for post-genomic approaches. We have constructed a DNA microarray for genome-wide gene expression analysis in fission...
Xue, Yongtao T., Haas, Stefan, Brino, Laurento, Gusnanto, Arief, Riemers, Mark, Talibi, Driss, ...
Completion of the fission yeast genome sequence has opened up possibilities for post-genomic approaches. We have constructed a DNA microarray for genome-wide gene expression analysis in fission...
Yoo, Eung Jae, Jin, Yong Hwan, Jang, Yeun Kyu, Bjerling, Pernilla, Tabish, Mohammad, Hong, Seung Hwan, ...
Hrp1 of Schizosaccharomyces pombe is a member of the CHD protein family, characterized by a chromodomain, a Myb-like telobox-related DNA-binding domain and a SNF2-related helicase/ATPase domain....
Positional regulation of mating-type genes in the fission yeast / (1994)
Thesis (Doctoral)--Uppsala University, 1994.
Oisson, Tim, Ekwall, Karl, Ruusala, Tarmo
We show that in fission yeast two DNA fragments at the silent P mating type locus provide plasmids with the capability of autonomous replication. Bacterial vectors containing these sequences...
The Domain Structure of Centromeres Is Conserved from Fission Yeast to Humans
Kniola, Barbara, O'Toole, Eileen, McIntosh, J. Richard, Mellone, Barbara, Allshire, Robin, Mengarelli, Silwa, ...
The centromeric DNA of fission yeast is arranged with a central core flanked by repeated sequences. The centromere-associated proteins, Mis6p and Cnp1p (SpCENP-A), associate exclusively with central...
Dang, Van Dinh, Benedik, Michael J., Ekwall, Karl, Choi, Jeannie, Allshire, Robin C., Levin, Henry L.
Tf1 is a long terminal repeat (LTR)-containing retrotransposon that propagates within the fission yeast Schizosaccharomyces pombe. LTR-retrotransposons possess significant similarity to retroviruses...
Yoo, Eung Jae, Jin, Yong Hwan, Jang, Yeun Kyu, Bjerling, Pernilla, Tabish, Mohammad, Hong, Seung Hwan, ...
Hrp1 of Schizosaccharomyces pombe is a member of the CHD protein family, characterized by a chromodomain, a Myb-like telobox-related DNA-binding domain and a SNF2-related helicase/ATPase domain. CHD...
Bjerling, Pernilla, Silverstein, Rebecca A., Thon, Geneviève, Caudy, Amy, Grewal, Shiv, Ekwall, Karl
Histone deacetylases (HDACs) are important for gene regulation and the maintenance of heterochromatin in eukaryotes. Schizosaccharomyces pombe was used as a model system to investigate the functional...
Dicer is required for chromosome segregation and gene silencing in fission yeast cells
Provost, Patrick, Silverstein, Rebecca A., Dishart, David, Walfridsson, Julian, Djupedal, Ingela, Kniola, Barbara, ...
RNA interference is a form of gene silencing in which the nuclease Dicer cleaves double-stranded RNA into small interfering RNAs. Here we report a role for Dicer in chromosome segregation of fission...
Bjerling, Pernilla, Silverstein, Rebecca A., Thon, Geneviève, Caudy, Amy, Grewal, Shiv, Ekwall, Karl
Nakayama, Jun-ichi, Xiao, Guoping, Noma, Ken-ichi, Malikzay, Asra, Bjerling, Pernilla, Ekwall, Karl, ...
The post-translational modifications of histones are key to the modulation of chromatin structure. Distinct patterns of modifications established by histone-modifying enzymes control diverse...
Carmichael, Jon B., Provost, Patrick, Ekwall, Karl, Hobman, Tom C.
In the fission yeast Schizosaccharomyces pombe, three genes that function in the RNA interference (RNAi) pathway, ago1+, dcr1+, and rdp1+, have recently been shown to be important for timely...
Bjerling, Pernilla, Ekwall, Karl, Egel, Richard, Thon, Geneviève
The mating-type region of the fission yeast Schizosaccharomyces pombe comprises three loci: mat1, mat2-P and mat3-M. mat1 is expressed and determines the mating type of the cell. mat2-P and mat3-M...
The CHD remodeling factor Hrp1 stimulates CENP-A loading to centromeres
Walfridsson, Julian, Bjerling, Pernilla, Thalen, Maria, Yoo, Eung-Jae, Park, Sang Dai, Ekwall, Karl
Centromeres of fission yeast are arranged with a central core DNA sequence flanked by repeated sequences. The centromere-associated histone H3 variant Cnp1 (SpCENP-A) binds exclusively to central...
Genomewide analysis of nucleosome density histone acetylation and HDAC function in fission yeast
Wirén, Marianna, Silverstein, Rebecca A, Sinha, Indranil, Walfridsson, Julian, Lee, Hang-mao, Laurenson, Patricia, ...
We have conducted a genomewide investigation into the enzymatic specificity, expression profiles, and binding locations of four histone deacetylases (HDACs), representing the three different...
RNA Pol II subunit Rpb7 promotes centromeric transcription and RNAi-directed chromatin silencing
Djupedal, Ingela, Portoso, Manuela, Spåhr, Henrik, Bonilla, Carolina, Gustafsson, Claes M., Allshire, Robin C., ...
Fission yeast centromeric repeats are transcribed into small interfering RNA (siRNA) precursors (pre-siRNAs), which are processed by Dicer to direct heterochromatin formation. Recently, Rpb1 and Rpb2...
The Domain Structure of Centromeres Is Conserved from Fission Yeast to Humans
Kniola, Barbara, O'Toole, Eileen, McIntosh, J. Richard, Mellone, Barbara, Allshire, Robin, Mengarelli, Silwa, ...
The centromeric DNA of fission yeast is arranged with a central core flanked by repeated sequences. The centromere-associated proteins, Mis6p and Cnp1p (SpCENP-A), associate exclusively with central...
Dang, Van Dinh, Benedik, Michael J., Ekwall, Karl, Choi, Jeannie, Allshire, Robin C., Levin, Henry L.
Tf1 is a long terminal repeat (LTR)-containing retrotransposon that propagates within the fission yeast Schizosaccharomyces pombe. LTR-retrotransposons possess significant similarity to retroviruses...
Yoo, Eung Jae, Jin, Yong Hwan, Jang, Yeun Kyu, Bjerling, Pernilla, Tabish, Mohammad, Hong, Seung Hwan, ...
Hrp1 of Schizosaccharomyces pombe is a member of the CHD protein family, characterized by a chromodomain, a Myb-like telobox-related DNA-binding domain and a SNF2-related helicase/ATPase domain. CHD...
Bjerling, Pernilla, Silverstein, Rebecca A., Thon, Geneviève, Caudy, Amy, Grewal, Shiv, Ekwall, Karl
Histone deacetylases (HDACs) are important for gene regulation and the maintenance of heterochromatin in eukaryotes. Schizosaccharomyces pombe was used as a model system to investigate the functional...
Dicer is required for chromosome segregation and gene silencing in fission yeast cells
Provost, Patrick, Silverstein, Rebecca A., Dishart, David, Walfridsson, Julian, Djupedal, Ingela, Kniola, Barbara, ...
RNA interference is a form of gene silencing in which the nuclease Dicer cleaves double-stranded RNA into small interfering RNAs. Here we report a role for Dicer in chromosome segregation of fission...
Bjerling, Pernilla, Silverstein, Rebecca A., Thon, Geneviève, Caudy, Amy, Grewal, Shiv, Ekwall, Karl
Nakayama, Jun-ichi, Xiao, Guoping, Noma, Ken-ichi, Malikzay, Asra, Bjerling, Pernilla, Ekwall, Karl, ...
The post-translational modifications of histones are key to the modulation of chromatin structure. Distinct patterns of modifications established by histone-modifying enzymes control diverse...
Carmichael, Jon B., Provost, Patrick, Ekwall, Karl, Hobman, Tom C.
In the fission yeast Schizosaccharomyces pombe, three genes that function in the RNA interference (RNAi) pathway, ago1+, dcr1+, and rdp1+, have recently been shown to be important for timely...
Bjerling, Pernilla, Ekwall, Karl, Egel, Richard, Thon, Geneviève
The mating-type region of the fission yeast Schizosaccharomyces pombe comprises three loci: mat1, mat2-P and mat3-M. mat1 is expressed and determines the mating type of the cell. mat2-P and mat3-M...
The CHD remodeling factor Hrp1 stimulates CENP-A loading to centromeres
Walfridsson, Julian, Bjerling, Pernilla, Thalen, Maria, Yoo, Eung-Jae, Park, Sang Dai, Ekwall, Karl
Centromeres of fission yeast are arranged with a central core DNA sequence flanked by repeated sequences. The centromere-associated histone H3 variant Cnp1 (SpCENP-A) binds exclusively to central...
Genomewide analysis of nucleosome density histone acetylation and HDAC function in fission yeast
Wirén, Marianna, Silverstein, Rebecca A, Sinha, Indranil, Walfridsson, Julian, Lee, Hang-mao, Laurenson, Patricia, ...
We have conducted a genomewide investigation into the enzymatic specificity, expression profiles, and binding locations of four histone deacetylases (HDACs), representing the three different...
RNA Pol II subunit Rpb7 promotes centromeric transcription and RNAi-directed chromatin silencing
Djupedal, Ingela, Portoso, Manuela, Spåhr, Henrik, Bonilla, Carolina, Gustafsson, Claes M., Allshire, Robin C., ...
Fission yeast centromeric repeats are transcribed into small interfering RNA (siRNA) precursors (pre-siRNAs), which are processed by Dicer to direct heterochromatin formation. Recently, Rpb1 and Rpb2...
Opel, Michael, Lando, David, Bonilla, Carolina, Trewick, Sarah C., Boukaba, Abdelhalim, Walfridsson, Julian, ...
In order to gain a more global view of the activity of histone demethylases, we report here genome-wide studies of the fission yeast SWIRM and polyamine oxidase (PAO) domain homologues of mammalian...
Fagerström-Billai, Fredrik, Durand-Dubief, Mikaël, Ekwall, Karl, Wright, Anthony P. H.
The Saccharomyces cerevisiae Ssn6 and Tup1 proteins form a corepressor complex that is recruited to target genes by DNA-bound repressor proteins. Repression occurs via several mechanisms, including...
Interaction of Epe1 With the Heterochromatin Assembly Pathway in Schizosaccharomyces pombe
Isaac, Sara, Walfridsson, Julian, Zohar, Tal, Lazar, David, Kahan, Tamar, Ekwall, Karl, ...
Epe1 is a JmjC domain protein that antagonizes heterochromatization in Schizosaccharomyces pombe. Related JmjC domain proteins catalyze a histone demethylation reaction that depends on Fe(II) and...
Dunleavy, Elaine M., Pidoux, Alison L., Monet, Marie, Bonilla, Carolina, Richardson, William, Hamilton, Georgina L., ...
A defining feature of centromeres is the presence of the histone H3 variant CENP-ACnp1. It is not known how CENP-ACnp1 is specifically delivered to, and assembled into, centromeric chromatin. Through...
Façanha, Anna L. Okorokova, Appelgren, Henrik, Tabish, Mohammad, Okorokov, Lev, Ekwall, Karl
Here we describe the phenotypic characterization of the cta4+ gene, encoding a novel member of the P4 family of P-type ATPases of fission yeast. The cta4Δ mutant is temperature sensitive and cold...
Durand-Dubief, Mickaël, Sinha, Indranil, Fagerström-Billai, Fredrik, Bonilla, Carolina, Wright, Anthony, Grunstein, Michael, ...
Expression profiling, ChiP–CHIP and phenotypic analysis were used to investigate the functional relationships of class III NAD+-dependent HDACs (Sirtuins) in fission yeast. We detected significant...
A genome-wide role for CHD remodelling factors and Nap1 in nucleosome disassembly
Walfridsson, Julian, Khorosjutina, Olga, Matikainen, Paulina, Gustafsson, Claes M, Ekwall, Karl
Chromatin remodelling factors and histone chaperones were previously shown to cooperatively affect nucleosome assembly and disassembly processes in vitro. Here, we show that Schizosaccharomyces pombe...
Cell-cycle regulation of cohesin stability along fission yeast chromosomes
Bernard, Pascal, Schmidt, Christine Katrin, Vaur, Sabine, Dheur, Sonia, Drogat, Julie, Genier, Sylvie, ...
Sister chromatid cohesion is mediated by cohesin, but the process of cohesion establishment during S-phase is still enigmatic. In mammalian cells, cohesin binding to chromatin is dynamic in G1, but...
Buchanan, Luke, Durand-Dubief, Mickaël, Roguev, Assen, Sakalar, Cagri, Wilhelm, Brian, Strålfors, Annelie, ...
Eukaryotic genomes are repetitively packaged into chromatin by nucleosomes, however they are regulated by the differences between nucleosomes, which establish various chromatin states. Local...