Karl Swärd

Publication List Details

Period

1997 - 2007

Number

16

Co-Authors

Disproportionally low clearance of macromolecules from the plasma to the peritoneal cavity in a mouse model of peritoneal dialysis (2007)

Rippe, Anna, Rippe, Catarina, Swärd, Karl, Rippe, Bengt

Background. This study was performed to establish a model for quantitative measurements of a number of basic peritoneal transport parameters, particularly transperitoneal clearances (Cl) of...

Disproportionally low clearance of macromolecules from the plasma to the peritoneal cavity in a mouse model of peritoneal dialysis (PD) (2006)

Rippe, Anna, Rippe, Catarina, Swärd, Karl, Rippe, Bengt

Background. This study was performed to establish a model for quantitative measurements of a number of basic peritoneal transport parameters, particularly transperitoneal clearances (Cl) of...

Disproportionally low clearance of macromolecules from the plasma to the peritoneal cavity in a mouse model of peritoneal dialysis (PD) (2006)

Rippe, Anna, Rippe, Catarina, Swärd, Karl, Rippe, Bengt

Background. This study was performed to establish a model for quantitative measurements of a number of basic peritoneal transport parameters, particularly transperitoneal clearances (Cl) of...

Influence of mitochondrial inhibition on global and local [Ca(2+)](I) in rat tail artery. (2002)

Swärd, Karl, Dreja, Karl, Lindqvist, Anders, Persson, Erik, Hellstrand, Per

Inhibition of oxidative metabolism is often found to decrease contractility of systemic vascular smooth muscle, but not to reduce global [Ca(2+)](i). In the present study, we probe the hypothesis...

Effects of oxygen tension on energetics of cultured vascular smooth muscle. (2002)

Lindqvist, Anders, Dreja, Karl, Swärd, Karl, Hellstrand, Per

Chronic hypoxia is a clinically important condition known to cause vascular abnormalities. To investigate the cellular mechanisms involved, we kept rings of a rat tail artery for 4 days in hypoxic...

Cholesterol depletion disrupts caveolae and differentially impairs agonist-induced arterial contraction. (2002)

Dreja, Karl, Voldstedlund, Marianne, Vinten, Jørgen, Tranum-Jensen, Jørgen, Hellstrand, Per, Swärd, Karl

OBJECTIVE: This study assessed the role of cholesterol-rich membrane regions, including caveolae, in the regulation of arterial contractility. Methods and Results- Rat tail artery devoid of...

Modulation of the calcium-force relationship in smooth muscle by polyamines and metabolic inhibition (1997)

Swärd, Karl

The relationship between intracellular free calcium ([Ca2+]i) and force in smooth muscle was investigated in receptor-coupled permeabilized preparations and by fluorimetry of the calcium indicator...

Modulation of the calcium-force relationship in smooth muscle by polyamines and metabolic inhibition (1997)

Swärd, Karl

The relationship between intracellular free calcium ([Ca2+]i) and force in smooth muscle was investigated in receptor-coupled permeabilized preparations and by fluorimetry of the calcium indicator...

An assay to evaluate the long-term effects of inflammatory mediators on murine airway smooth muscle: evidence that TNFα up-regulates 5-HT2A-mediated contraction

Adner, Mikael, Rose, Andrew C, Zhang, Yaping, Swärd, Karl, Benson, Mikael, Uddman, Rolf, ...

Asthma research is arguably limited by an absence of appropriate animal models to study the pharmacology of inflammatory mediators that affect airway hyperresponsiveness and remodelling. Here we...

Inhibition of Rho-associated kinase blocks agonist-induced Ca2+ sensitization of myosin phosphorylation and force in guinea-pig ileum

Swärd, Karl, Dreja, Karl, Susnjar, Marija, Hellstrand, Per, Hartshorne, David J, Walsh, Michael P

Ca2+ sensitization of smooth muscle contraction involves the small GTPase RhoA, inhibition of myosin light chain phosphatase (MLCP) and enhanced myosin regulatory light chain (LC20) phosphorylation....