The C. elegans Opa1 Homologue EAT-3 is Essential for Resistance to Free Radicals (2008)
Takayuki Kanazawa, Mauro Zappaterra, Ayako Hasegawa, Ashley P Wright, Erin D Newman-Smith, Karolyn F Buttle, ...
The most prevalent form of hereditary blindness, Dominant Optic Atrophy, is caused by mutations in the mitochondrial dynamin family member Opa1. Mutations in Opa1 and a homologous protein in yeast...
Marsh, Brad J., Mastronarde, David N., Buttle, Karolyn F., Howell, Kathryn E., McIntosh, J. Richard
The positional relationships among all of the visible organelles in a densely packed region of cytoplasm from an insulin secreting, cultured mammalian cell have been analyzed in three dimensions...
Mootha, Vamsi K., Wei, Michael C., Buttle, Karolyn F., Scorrano, Luca, Panoutsakopoulou, Vily, Mannella, Carmen A., ...
Multiple apoptotic pathways release cytochrome c from the mitochondrial intermembrane space, resulting in the activation of downstream caspases. In vivo activation of Fas (CD95) resulted in...
Marsh, Brad J., Mastronarde, David N., Buttle, Karolyn F., Howell, Kathryn E., McIntosh, J. Richard
The positional relationships among all of the visible organelles in a densely packed region of cytoplasm from an insulin secreting, cultured mammalian cell have been analyzed in three dimensions...
Mootha, Vamsi K., Wei, Michael C., Buttle, Karolyn F., Scorrano, Luca, Panoutsakopoulou, Vily, Mannella, Carmen A., ...
Multiple apoptotic pathways release cytochrome c from the mitochondrial intermembrane space, resulting in the activation of downstream caspases. In vivo activation of Fas (CD95) resulted in...
Csordás, György, Renken, Christian, Várnai, Péter, Walter, Ludivine, Weaver, David, Buttle, Karolyn F., ...
The role of mitochondria in cell metabolism and survival is controlled by calcium signals that are commonly transmitted at the close associations between mitochondria and endoplasmic reticulum (ER)....
The C. elegans Opa1 Homologue EAT-3 Is Essential for Resistance to Free Radicals
Kanazawa, Takayuki, Zappaterra, Mauro D., Hasegawa, Ayako, Wright, Ashley P., Newman-Smith, Erin D., Buttle, Karolyn F., ...
The C. elegans eat-3 gene encodes a mitochondrial dynamin family member homologous to Opa1 in humans and Mgm1 in yeast. We find that mutations in the C. elegans eat-3 locus cause mitochondria to...
Chromosome Fragments Possessing Only One Kinetochore Can Congress to the Spindle Equator
Khodjakov, Alexey, Cole, Richard W., McEwen, Bruce F., Buttle, Karolyn F., Rieder, Conly L.
We used laser microsurgery to cut between the two sister kinetochores on bioriented prometaphase chromosomes to produce two chromosome fragments containing one kinetochore (CF1K). Each of these CF1Ks...
McEwen, Bruce F., Heagle, Amy B., Cassels, Grisel O., Buttle, Karolyn F., Rieder, Conly L.
Kinetochore microtubules (kMts) are a subset of spindle microtubules that bind directly to the kinetochore to form the kinetochore fiber (K-fiber). The K-fiber in turn interacts with the kinetochore...