Population pharmacokinetics of artesunate and amodiaquine in African children (2009)
Stepniewska, Kasia, Taylor, Walter, Sirima, Sodiomon B, Ouedraogo, Esperance B, Ouedraogo, Alphonse, Gansané, Adama, ...
Abstract Background Pharmacokinetic (PK) data on amodiaquine (AQ) and artesunate (AS) are limited in children, an important risk group for malaria. The aim of this study was to evaluate the PK...
Plasmodium falciparumgametocyte dynamics in areas of different malaria endemicity (2008)
Stepniewska, Kasia, Price, Ric N, Sutherland, Colin J, Drakeley, Chris J, Von Seidlein, Lorenz, Nosten, Francois, ...
Abstract Background The aim of this study was to identify and compare factors associated with Plasmodium falciparum gametocyte carriage in three regions of differing malaria endemicity. Methods...
Lee, Sue J, Stepniewska, Kasia, Anstey, Nicholas, Ashley, Elizabeth, Barnes, Karen, Binh, Tran, ...
Abstract Background Malaria is a very important cause of anaemia in tropical countries. Anaemia is assessed either by measurement of the haematocrit or the haemoglobin concentration. For comparisons...
World Antimalarial Resistance Network I: Clinical efficacy of antimalarial drugs (2007)
Price, Ric N, Dorsey, Grant, Ashley, Elizabeth A, Barnes, Karen I, Baird, J Kevin, D'Alessandro, Umberto, ...
Abstract The proliferation of antimalarial drug trials in the last ten years provides the opportunity to launch a concerted global surveillance effort to monitor antimalarial drug efficacy. The...
Stepniewska, Kasia, Chotivanich, Kesinee, Brockman, Alan, Day, Nicholas PJ, White, Nicholas J
Abstract Conventional methods of assessing in-vitro antimalarial drug-concentration effect relationships in field testing of fresh isolates assess each parasite isolate individually. This leads to...
Stepniewska, Kasia, White, Nicholas J
Abstract Background Treatments for uncomplicated falciparum malaria should have high cure rates. The World Health Organization has recently set a target cure rate of 95% assessed at 28 days. The use...
In Vivo Assessment of Drug Efficacy against Plasmodium falciparum Malaria: Duration of Follow-Up
Stepniewska, Kasia, Taylor, Walter R.J., Mayxay, Mayfong, Price, Ric, Smithuis, Frank, Guthmann, Jean-Paul, ...
To determine the optimum duration of follow-up for the assessment of drug efficacy against Plasmodium falciparum malaria, 96 trial arms from randomized controlled trials (RCTs) with follow-up of 28...
Chaowagul, Wipada, Chierakul, Wirongrong, Simpson, Andrew J., Short, Jennifer M., Stepniewska, Kasia, Maharjan, Bina, ...
Melioidosis (infection caused by Burkholderia pseudomallei) requires a prolonged course of oral antibiotics following initial intravenous therapy to reduce the risk of relapse after cessation of...
Ashley, Elizabeth A., Stepniewska, Kasia, Lindegårdh, Niklas, McGready, Rose, Hutagalung, Robert, Hae, Rae, ...
A fixed artesunate-mefloquine combination, comprising three daily doses of 8 mg of mefloquine/kg of body weight and 4 mg of artesunate/kg, has been developed recently. This study was designed to...
In Vivo Assessment of Drug Efficacy against Plasmodium falciparum Malaria: Duration of Follow-Up
Stepniewska, Kasia, Taylor, Walter R.J., Mayxay, Mayfong, Price, Ric, Smithuis, Frank, Guthmann, Jean-Paul, ...
To determine the optimum duration of follow-up for the assessment of drug efficacy against Plasmodium falciparum malaria, 96 trial arms from randomized controlled trials (RCTs) with follow-up of 28...
Chaowagul, Wipada, Chierakul, Wirongrong, Simpson, Andrew J., Short, Jennifer M., Stepniewska, Kasia, Maharjan, Bina, ...
Melioidosis (infection caused by Burkholderia pseudomallei) requires a prolonged course of oral antibiotics following initial intravenous therapy to reduce the risk of relapse after cessation of...
Ashley, Elizabeth A., Stepniewska, Kasia, Lindegårdh, Niklas, McGready, Rose, Hutagalung, Robert, Hae, Rae, ...
A fixed artesunate-mefloquine combination, comprising three daily doses of 8 mg of mefloquine/kg of body weight and 4 mg of artesunate/kg, has been developed recently. This study was designed to...
Stepniewska, Kasia, Chotivanich, Kesinee, Brockman, Alan, Day, Nicholas PJ, White, Nicholas J
Conventional methods of assessing in-vitro antimalarial drug-concentration effect relationships in field testing of fresh isolates assess each parasite isolate individually. This leads to systematic...
Caws, Maxine, Thwaites, Guy, Stepniewska, Kasia, Lan, Nguyen Thi Ngoc, Duyen, Nguyen Thi Hong, Phuong, Nguyen Thi, ...
Multidrug-resistant tuberculous meningitis is fatal without rapid diagnosis and use of second-line therapy. It is more common in human immunodeficiency virus (HIV)-positive patients. Beijing genotype...
Pandit, Anil, Arjyal, Amit, Day, Jeremy N., Paudyal, Buddhi, Dangol, Sabina, Zimmerman, Mark D., ...
Evaluation of the Wayson Stain for the Rapid Diagnosis of Melioidosis▿
Sheridan, Elizabeth A., Ramsay, Andrew R., Short, Jennifer M., Stepniewska, Kasia, Wuthiekanun, Vanaporn, Simpson, Andrew J. H.
World Antimalarial Resistance Network I: Clinical efficacy of antimalarial drugs
Price, Ric N, Dorsey, Grant, Ashley, Elizabeth A, Barnes, Karen I, Baird, J Kevin, D'Alessandro, Umberto, ...
The proliferation of antimalarial drug trials in the last ten years provides the opportunity to launch a concerted global surveillance effort to monitor antimalarial drug efficacy. The diversity of...
Caws, Maxine, Thwaites, Guy, Dunstan, Sarah, Hawn, Thomas R., Thi Ngoc Lan, Nguyen, Thuong, Nguyen Thuy Thuong, ...
The factors that govern the development of tuberculosis disease are incompletely understood. We hypothesized that some strains of Mycobacterium tuberculosis (M. tuberculosis) are more capable of...
Dolecek, Christiane, Phi La, Tran Thi, Rang, Nguyen Ngoc, Phuong, Le Thi, Vinh, Ha, Tuan, Phung Quoc, ...
Lee, Sue J, Stepniewska, Kasia, Anstey, Nicholas, Ashley, Elizabeth, Barnes, Karen, Binh, Tran Quang, ...
Taylor, Walter R. J., Thinh, Bui Nghia, Anh, Giang Thuc, Horby, Peter, Wertheim, Heiman, Lindegardh, Niklas, ...
In the absence of a parenteral drug, oral oseltamivir is currently recommended by the WHO for treating H5N1 influenza. Whether oseltamivir absorption is adequate in severe influenza is unknown. We...
Plasmodium falciparum gametocyte dynamics in areas of different malaria endemicity
Stepniewska, Kasia, Price, Ric N, Sutherland, Colin J, Drakeley, Chris J, Von Seidlein, Lorenz, Nosten, Francois, ...