Katharina Domschke

Reduced amygdala–prefrontal coupling in major depression: association with MAOA genotype and illness severity (2009)

Dannlowski, Udo, Ohrmann, Patricia, Konrad, Carsten, Domschke, Katharina, Bauer, Jochen, Kugel, Harald, ...

The amygdala plays a pivotal role in a cortico-limbic circuitry implicated in emotion processing and regulation. In the present study, functional connectivity of the amygdala with prefrontal areas...

A genomewide association study points to multiple loci that predict antidepressant drug treatment outcome in depression (2009)

Ising, Marcus, Lucae, Susanne, Binder, Elisabeth B., Bettecken, Thomas, Uhr, Manfred, Ripke, Stephan, ...

CONTEXT: The efficacy of antidepressant drug treatment in depression is unsatisfactory; 1 in 3 patients does not fully recover even after several treatment trials. Genetic factors and clinical...

Association of MAO-A variant with complicated grief in major depression (2007)

Kersting, Anette, Kroker, Kristin, Horstmann, Julia, Baune, Bernhard T., Hohoff, Christa, Mortensen, Lena Sünke, ...

Background/Aims: It has been suggested that monoamine oxidase A (MAO-A) activity is involved in the pathogenesis of major depression. Bereavement-related complicated grief significantly increases the...

Genomische Charakterisierung, systematisches Mutationsscreening und Assoziationsstudie des CREM-Gens bei Patienten mit Panikstörung (2004)

Domschke, Katharina

Panikstörung ist eine Angsterkrankung mit einer Heritabilität von ca. 48%. Knock-out Mäuse für das 'C-AMP Responsive Element Modulator' (CREM) Gen zeigen ein niedrigeres Angstniveau als...