Katharina Spanel-Borowski

Reduction in corpora lutea number in obese melanocortin-4-receptor-deficient mice (2009)

Sandrock, Mara, Schulz, Angela, Merkwitz, Claudia, Schöneberg, Torsten, Spanel-Borowski, Katharina, Ricken, Albert

Abstract Obese melanocortin-4-receptor-deficient (MC4R-/-) male mice are reported to have erectile dysfunction, while homozygous MC4R-/- female mice are apparently fertile. A recently established...

Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes (2008)

Spanel-Borowski, Katharina, Smith, Mark A., Simone, Cristiano, Simonsen, Anne, Simon, Hans-Uwe, ...

Research in autophagy continues to accelerate, and as a result many new scientists are entering the field. Accordingly, it is important to establish a standard set of criteria for monitoring...

Evidence of leptin expression in normal and polycystic human ovaries (2001)

Löffler, Sabine, Aust, Gabriela, Köhler, Uwe, Spanel-Borowski, Katharina

Leptin, the `obese' protein, is found in cultured granulosa cells derived from human pre-ovulatory follicles. However, the occurrence of leptin has not been studied in intact ovaries, either normal...

Eosinophils in the human corpus luteum: the role of RANTES and eotaxin in eosinophil attraction into periovulatory structures (2000)

Aust, Gabriela, Simchen, Cornelia, Heider, Ulrike, Hmeidan, Fayez A., Blumenauer, Veronika, Spanel-Borowski, Katharina

We evaluated the presence and number of eosinophils at varying stages in the human corpus luteum from 27 ovaries of women at reproductive age. Eosinophils preferentially accumulated in dilated...

Novel NKX2–5 Mutations in Diseased Heart Tissues of Patients with Cardiac Malformations

Reamon-Buettner, Stella Marie, Hecker, Hartmut, Spanel-Borowski, Katharina, Craatz, Steffen, Kuenzel, Eberhard, Borlak, Juergen

NKX2–5 is a homeodomain-containing transcription factor important in cardiac development. Familial mutations in the NKX2–5 gene are associated with cardiac abnormalities, but mutations are rare...

Reduction in corpora lutea number in obese melanocortin-4-receptor-deficient mice

Sandrock, Mara, Schulz, Angela, Merkwitz, Claudia, Schöneberg, Torsten, Spanel-Borowski, Katharina, Ricken, Albert

Obese melanocortin-4-receptor-deficient (MC4R-/-) male mice are reported to have erectile dysfunction, while homozygous MC4R-/- female mice are apparently fertile. A recently established obese mouse...