Yosaatmadja, Francisca, Andrews, Katherine T, Duffy, Michael F, Brown, Graham V, Beeson, James G, Rogerson, Stephen J
Abstract Background Malaria in pregnancy is characterized by accumulation of infected erythrocytes (IE) in the placenta. The key ligand identified as mediating this process is a Plasmodium falciparum...
RAP1 controls rhoptry targeting of RAP2 in the malaria parasite Plasmodium falciparum
Baldi, Deborah L., Andrews, Katherine T., Waller, Ross F., Roos, David S., Howard, Randall F., Crabb, Brendan S., ...
Rhoptry associated protein 1 (RAP1) and 2 (RAP2), together with a poorly described third protein RAP3, form the low molecular weight complex within the rhoptries of Plasmodium falciparum. These...
Direct Activation of Human Endothelial Cells by Plasmodium falciparum-Infected Erythrocytes
Viebig, Nicola K., Wulbrand, Ulrich, Förster, Reinhold, Andrews, Katherine T., Lanzer, Michael, Knolle, Percy A.
Cytoadherence of Plasmodium falciparum-infected erythrocytes (PRBC) to endothelial cells causes severe clinical disease, presumably as a of result perfusion failure and tissue hypoxia. Cytoadherence...
Andrews, Katherine T., Fairlie, David P., Madala, Praveen K., Ray, John, Wyatt, David M., Hilton, Petrina M., ...
Parasite resistance to antimalarial drugs is a serious threat to human health, and novel agents that act on enzymes essential for parasite metabolism, such as proteases, are attractive targets for...
Andrews, Katherine T., Klatt, Nicole, Adams, Yvonne, Mischnick, Petra, Schwartz-Albiez, Reinhard
Adhesion of Plasmodium falciparum-infected erythrocytes to placental chondroitin 4-sulfate (CSA) has been linked to the severe disease outcome of pregnancy-associated malaria. Soluble polysaccharides...
Adams, Yvonne, Freeman, Craig, Schwartz-Albiez, Reinhard, Ferro, Vito, Parish, Christopher R., Andrews, Katherine T.
A panel of sulfated oligosaccharides was tested for antimalarial activity and inhibition of adhesion to the placental malaria receptor chondroitin-4-sulfate (CSA). The heparan sulfate mimetic PI-88,...
RAP1 controls rhoptry targeting of RAP2 in the malaria parasite Plasmodium falciparum
Baldi, Deborah L., Andrews, Katherine T., Waller, Ross F., Roos, David S., Howard, Randall F., Crabb, Brendan S., ...
Rhoptry associated protein 1 (RAP1) and 2 (RAP2), together with a poorly described third protein RAP3, form the low molecular weight complex within the rhoptries of Plasmodium falciparum. These...
Direct Activation of Human Endothelial Cells by Plasmodium falciparum-Infected Erythrocytes
Viebig, Nicola K., Wulbrand, Ulrich, Förster, Reinhold, Andrews, Katherine T., Lanzer, Michael, Knolle, Percy A.
Cytoadherence of Plasmodium falciparum-infected erythrocytes (PRBC) to endothelial cells causes severe clinical disease, presumably as a of result perfusion failure and tissue hypoxia. Cytoadherence...
Andrews, Katherine T., Klatt, Nicole, Adams, Yvonne, Mischnick, Petra, Schwartz-Albiez, Reinhard
Adhesion of Plasmodium falciparum-infected erythrocytes to placental chondroitin 4-sulfate (CSA) has been linked to the severe disease outcome of pregnancy-associated malaria. Soluble polysaccharides...
Andrews, Katherine T., Fairlie, David P., Madala, Praveen K., Ray, John, Wyatt, David M., Hilton, Petrina M., ...
Parasite resistance to antimalarial drugs is a serious threat to human health, and novel agents that act on enzymes essential for parasite metabolism, such as proteases, are attractive targets for...
Adams, Yvonne, Freeman, Craig, Schwartz-Albiez, Reinhard, Ferro, Vito, Parish, Christopher R., Andrews, Katherine T.
A panel of sulfated oligosaccharides was tested for antimalarial activity and inhibition of adhesion to the placental malaria receptor chondroitin-4-sulfate (CSA). The heparan sulfate mimetic PI-88,...