Mason, Mike J, Fan, Guoping, Plath, Kathrin, Zhou, Qing, Horvath, Steve
Abstract Background Recent work has revealed that a core group of transcription factors (TFs) regulates the key characteristics of embryonic stem (ES) cells: pluripotency and self-renewal. Current...
Bradley E. Bernstein, Tarjei S. Mikkelsen, Xiaohui Xie, Michael Kamal, Dana J. Huebert, James Cuff, ...
The most highly conserved noncoding elements (HCNEs) in mammalian genomes cluster within regions enriched for genes encoding developmentally important transcription factors (TFs). This suggests that...
Zum Mechanismus der Translokation von Proteinen in das Endoplasmatische Retikulum der Hefe (1999)
In der Hefe Saccharomyces cerevisiae können Proteine entweder co- oder posttranslational durch die Membran des Endoplasmatischen Retikulum transportiert werden. Sie besitzen eine Signalsequenz, die...
Zum Mechanismus der Translokation von Proteinen in das Endoplasmatische Retikulum der Hefe (1999)
In der Hefe Saccharomyces cerevisiae können Proteine entweder co- oder posttranslational durch die Membran des Endoplasmatischen Retikulum transportiert werden. Sie besitzen eine Signalsequenz, die...
Zum Mechanismus der Translokation von Proteinen in das endoplasmatische Retikulum der Hefe / (1999)
Berlin, Humboldt-Universiẗat, Diss., 1999.
Plath, Kathrin, Wilkinson, Barrie M., Stirling, Colin J., Rapoport, Tom A.
Posttranslational translocation of prepro-α-factor (ppαF) across the yeast endoplasmic reticulum membrane begins with the binding of the signal sequence to the Sec complex, a membrane component...
Plath, Kathrin, Wilkinson, Barrie M., Stirling, Colin J., Rapoport, Tom A.
Posttranslational translocation of prepro-α-factor (ppαF) across the yeast endoplasmic reticulum membrane begins with the binding of the signal sequence to the Sec complex, a membrane component...
Plath, Kathrin, Talbot, Dale, Hamer, Karien M., Otte, Arie P., Yang, Thomas P., Jaenisch, Rudolf, ...
Polycomb group (PcG) proteins belonging to the polycomb (Pc) repressive complexes 1 and 2 (PRC1 and PRC2) maintain homeotic gene silencing. In Drosophila, PRC2 methylates histone H3 on lysine 27, and...
Plath, Kathrin, Rapoport, Tom A.
In posttranslational translocation in yeast, completed protein substrates are transported across the endoplasmic reticulum membrane through a translocation channel formed by the Sec complex. We have...
Post-Translational Regulation of Oct4 Transcriptional Activity
Saxe, Jonathan P., Tomilin, Alexey, Schöler, Hans R., Plath, Kathrin, Huang, Jing
Oct4 is a key component of the molecular circuitry which regulates embryonic stem cell proliferation and differentiation. It is essential for maintenance of undifferentiated, pluripotent cell...
X chromosome inactivation in the absence of Dicer
Kanellopoulou, Chryssa, Muljo, Stefan A., Dimitrov, Stoil D., Chen, Xi, Colin, Christian, Plath, Kathrin, ...
Dicer is central to the RNA interference (RNAi) pathway, because it is required for processing of double-stranded RNA (dsRNA) precursors into small RNA effector molecules. In principle, any long...