The effect of histones on initiation of E. coli RNA polymerase on T7 DNA (1978)
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Eaton, Kathryn A., Ringler, Susan R., Danon, Stephen J.
The goal of this study was to evaluate the role of host immunity in gastritis and epithelial damage due to Helicobacter pylori. Splenocytes from H. pylori-infected and uninfected C57BL/6 mice were...
Eaton, Kathryn A., Mefford, Megan E.
Vaccination suppresses Helicobacter pylori colonization but does not cure infection. Furthermore, postvaccination gastritis, likely induced by enhanced host response to residual colonization, may...
Role of Helicobacter pylori cag Region Genes in Colonization and Gastritis in Two Animal Models
Eaton, Kathryn A., Kersulyte, Dange, Mefford, Megan, Danon, Stephen J., Krakowka, Steven, Berg, Douglas E.
The Helicobacter pylori chromosomal region known as the cytotoxin-gene associated pathogenicity island (cag PAI) is associated with severe disease and encodes proteins that are believed to induce...
Josenhans, Christine, Eaton, Kathryn A., Thevenot, Tracy, Suerbaum, Sebastian
The genome of Helicobacter pylori contains numerous simple nucleotide repeats that have been proposed to have regulatory functions and to compensate for the conspicuous dearth of master regulatory...
Joyce, Elizabeth A., Gilbert, Joanne V., Eaton, Kathryn A., Plaut, Andrew, Wright, Andrew
Infection with Helicobacter pylori strains containing the cag Pathogenicity Island (cag PAI) is strongly correlated with the development of severe gastric disease, including gastric and duodenal...
In Vivo Complementation of ureB Restores the Ability of Helicobacter pylori To Colonize
Eaton, Kathryn A., Gilbert, Joanne V., Joyce, Elizabeth A., Wanken, Amy E., Thevenot, Tracy, Baker, Patrick, ...
The objective of this study was to determine (i) if complementation of ureB-negative Helicobacter pylori restores colonization and (ii) if urease is a useful reporter for promoter activity in vivo....
The Entner-Doudoroff Pathway Has Little Effect on Helicobacter pylori Colonization of Mice
Wanken, Amy E., Conway, Tyrrell, Eaton, Kathryn A.
Helicobacter pylori mutants deficient in 6-phosphogluconate dehydratase (6PGD) were constructed. Colonization densities were lower and minimum infectious doses were higher for mutant strains than for...
Dailidiene, Daiva, Dailide, Giedrius, Ogura, Keiji, Zhang, Maojun, Mukhopadhyay, Asish K., Eaton, Kathryn A., ...
Insights into bacterium-host interactions and genome evolution can emerge from comparisons among related species. Here we studied Helicobacter acinonychis (formerly H. acinonyx), a species closely...
Modulation of Host Immune Responses by the Cytolethal Distending Toxin of Helicobacter hepaticus
Pratt, Jason S., Sachen, Kacey L., Wood, Heather D., Eaton, Kathryn A., Young, Vincent B.
Persistent murine infection with Helicobacter hepaticus leads to chronic gastrointestinal inflammation and neoplasia in susceptible strains. To determine the role of the virulence factor cytolethal...
Eaton, Kathryn A., Benson, Lucy H., Haeger, Jennifer, Gray, Brian M.
Gastritis due to Helicobacter pylori is induced by a Th1-mediated response that is CD4 cell and gamma interferon (IFN-γ) dependent. T-bet is a transcription factor that directs differentiation of...
Eaton, Kathryn A., Ringler, Susan R., Danon, Stephen J.
The goal of this study was to evaluate the role of host immunity in gastritis and epithelial damage due to Helicobacter pylori. Splenocytes from H. pylori-infected and uninfected C57BL/6 mice were...
Eaton, Kathryn A., Mefford, Megan E.
Vaccination suppresses Helicobacter pylori colonization but does not cure infection. Furthermore, postvaccination gastritis, likely induced by enhanced host response to residual colonization, may...
Role of Helicobacter pylori cag Region Genes in Colonization and Gastritis in Two Animal Models
Eaton, Kathryn A., Kersulyte, Dange, Mefford, Megan, Danon, Stephen J., Krakowka, Steven, Berg, Douglas E.
The Helicobacter pylori chromosomal region known as the cytotoxin-gene associated pathogenicity island (cag PAI) is associated with severe disease and encodes proteins that are believed to induce...
Josenhans, Christine, Eaton, Kathryn A., Thevenot, Tracy, Suerbaum, Sebastian
The genome of Helicobacter pylori contains numerous simple nucleotide repeats that have been proposed to have regulatory functions and to compensate for the conspicuous dearth of master regulatory...
Joyce, Elizabeth A., Gilbert, Joanne V., Eaton, Kathryn A., Plaut, Andrew, Wright, Andrew
Infection with Helicobacter pylori strains containing the cag Pathogenicity Island (cag PAI) is strongly correlated with the development of severe gastric disease, including gastric and duodenal...
In Vivo Complementation of ureB Restores the Ability of Helicobacter pylori To Colonize
Eaton, Kathryn A., Gilbert, Joanne V., Joyce, Elizabeth A., Wanken, Amy E., Thevenot, Tracy, Baker, Patrick, ...
The objective of this study was to determine (i) if complementation of ureB-negative Helicobacter pylori restores colonization and (ii) if urease is a useful reporter for promoter activity in vivo....
The Entner-Doudoroff Pathway Has Little Effect on Helicobacter pylori Colonization of Mice
Wanken, Amy E., Conway, Tyrrell, Eaton, Kathryn A.
Helicobacter pylori mutants deficient in 6-phosphogluconate dehydratase (6PGD) were constructed. Colonization densities were lower and minimum infectious doses were higher for mutant strains than for...
Dailidiene, Daiva, Dailide, Giedrius, Ogura, Keiji, Zhang, Maojun, Mukhopadhyay, Asish K., Eaton, Kathryn A., ...
Insights into bacterium-host interactions and genome evolution can emerge from comparisons among related species. Here we studied Helicobacter acinonychis (formerly H. acinonyx), a species closely...
Modulation of Host Immune Responses by the Cytolethal Distending Toxin of Helicobacter hepaticus
Pratt, Jason S., Sachen, Kacey L., Wood, Heather D., Eaton, Kathryn A., Young, Vincent B.
Persistent murine infection with Helicobacter hepaticus leads to chronic gastrointestinal inflammation and neoplasia in susceptible strains. To determine the role of the virulence factor cytolethal...
Eaton, Kathryn A., Benson, Lucy H., Haeger, Jennifer, Gray, Brian M.
Gastritis due to Helicobacter pylori is induced by a Th1-mediated response that is CD4 cell and gamma interferon (IFN-γ) dependent. T-bet is a transcription factor that directs differentiation of...
Pathogenesis of Renal Disease Due to Enterohemorrhagic Escherichia coli in Germ-Free Mice▿
Eaton, Kathryn A., Friedman, David I., Francis, Gayle J., Tyler, Jessica S., Young, Vincent B., Haeger, Jennifer, ...
Enterohemorrhagic Escherichia coli (EHEC) is a food-borne pathogen that causes hemorrhagic colitis and acute renal failure. We used a germ-free mouse model to investigate the role of host factors,...
Alamuri, Praveen, Eaton, Kathryn A., Himpsl, Stephanie D., Smith, Sara N., Mobley, Harry L. T.
Complicated urinary tract infections (UTI) caused by Proteus mirabilis are associated with severe pathology in the bladder and kidney. To investigate the roles of two established cytotoxins, the HpmA...