Ian J. Donaldson, Michael Chapman, Sarah Kinston, Josette Renée L, Kathy Knezevic, Ie Piltz, ...
identification of cis-regulatory sequences controlling
Donaldson, Ian J., Chapman, Michael, Kinston, Sarah, Landry, Josette Renée, Knezevic, Kathy, Piltz, Sandie, ...
The development of blood has long served as a model for mammalian cell type specification and differentiation, and yet the underlying transcriptional networks remain ill defined. Characterization of...
Donaldson, Ian J., Chapman, Michael, Kinston, Sarah, Landry, Josette Renée, Knezevic, Kathy, Piltz, Sandie, ...
The development of blood has long served as a model for mammalian cell type specification and differentiation, and yet the underlying transcriptional networks remain ill defined. Characterisation of...
Göttgens, Berthold, Broccardo, Cyril, Sanchez, Maria-Jose, Deveaux, Sophie, Murphy, George, Göthert, Joachim R., ...
Analysis of cis-regulatory elements is central to understanding the genomic program for development. The scl/tal-1 transcription factor is essential for lineage commitment to blood cell formation and...
Göttgens, Berthold, Broccardo, Cyril, Sanchez, Maria-Jose, Deveaux, Sophie, Murphy, George, Göthert, Joachim R., ...
Analysis of cis-regulatory elements is central to understanding the genomic program for development. The scl/tal-1 transcription factor is essential for lineage commitment to blood cell formation and...
The SCL transcriptional network and BMP signaling pathway interact to regulate RUNX1 activity
Pimanda, John E., Donaldson, Ian J., Kinston, Sarah, Knezevic, Kathy, Huckle, Liz, ...
Hematopoietic stem cell (HSC) development is regulated by several signaling pathways and a number of key transcription factors, which include Scl/Tal1, Runx1, and members of the Smad family. However,...
Pimanda, John E., Ottersbach, Katrin, Knezevic, Kathy, Kinston, Sarah, Chan, Wan Y. I., Wilson, Nicola K., ...
Conservation of the vertebrate body plan has been attributed to the evolutionary stability of gene-regulatory networks (GRNs). We describe a regulatory circuit made up of Gata2, Fli1, and Scl/Tal1...