Karlsson, Jenny, Pütsep, Katrin, Chu, Hiutung, Kays, Robert J, Bevins, Charles L, Andersson, Mats
Abstract Background Enteric antimicrobial peptides secreted from Paneth cells, including α-defensins (in mice named cryptdins), are key effector molecules of innate immunity in the small intestine....
Developmental switch of intestinal antimicrobial peptide expression
Ménard, Sandrine, Förster, Valentina, Lotz, Michael, Gütle, Dominique, Duerr, Claudia U., Gallo, Richard L., ...
Paneth cell–derived enteric antimicrobial peptides provide protection from intestinal infection and maintenance of enteric homeostasis. Paneth cells, however, evolve only after the neonatal period,...