Katrina T. Forest

Aquifex aeolicus PilT, Homologue of a Surface Motility Protein, Is a Thermostable Oligomeric NTPase

Herdendorf, Timothy J., McCaslin, Darrell R., Forest, Katrina T.

Bacterial surface motility works by retraction of surface-attached type IV pili. This retraction requires the PilT protein, a member of a large family of putative NTPases from type II and IV...

Functional Dissection of a Conserved Motif within the Pilus Retraction Protein PilT†

Aukema, Kelly G., Kron, Erin M., Herdendorf, Timothy J., Forest, Katrina T.

PilT is a hexameric ATPase required for type IV pilus retraction in gram-negative bacteria. Retraction of type IV pili mediates intimate attachment to and signaling in host cells, surface motility,...

Aquifex aeolicus PilT, Homologue of a Surface Motility Protein, Is a Thermostable Oligomeric NTPase

Herdendorf, Timothy J., McCaslin, Darrell R., Forest, Katrina T.

Bacterial surface motility works by retraction of surface-attached type IV pili. This retraction requires the PilT protein, a member of a large family of putative NTPases from type II and IV...

Functional Dissection of a Conserved Motif within the Pilus Retraction Protein PilT†

Aukema, Kelly G., Kron, Erin M., Herdendorf, Timothy J., Forest, Katrina T.

PilT is a hexameric ATPase required for type IV pilus retraction in gram-negative bacteria. Retraction of type IV pili mediates intimate attachment to and signaling in host cells, surface motility,...

Conserved Regions from Neisseria gonorrhoeae Pilin Are Immunosilent and Not Immunosuppressive▿

Hansen, Johanna K., Demick, Karen P., Mansfield, John M., Forest, Katrina T.

PilE is the primary subunit of type IV pili from Neisseria gonorrhoeae and contains a surface-exposed hypervariable region thought to be one feature of pili that has prevented development of a...

3D structure/function analysis of PilX reveals how minor pilins can modulate the virulence properties of type IV pili

Helaine, Sophie, Dyer, David H., Nassif, Xavier, Pelicic, Vladimir, Forest, Katrina T.

Type IV pili (Tfp) are widespread filamentous bacterial organelles that mediate multiple virulence-related phenotypes. They are composed mainly of pilin subunits, which are processed before filament...

Conformational changes of glucose/galactose-binding protein illuminated by open, unliganded, and ultra-high-resolution ligand-bound structures

Borrok, M. Jack, Kiessling, Laura L., Forest, Katrina T.

D-Glucose/D-Galactose-binding protein (GGBP) mediates chemotaxis toward and active transport of glucose and galactose in a number of bacterial species. GGBP, like other periplasmic binding proteins,...

Extracellular Bacterial Pathogen Induces Host Cell Surface Reorganization to Resist Shear Stress

Mikaty, Guillain, Soyer, Magali, Mairey, Emilie, Henry, Nelly, Dyer, Dave, Forest, Katrina T., ...

Bacterial infections targeting the bloodstream lead to a wide array of devastating diseases such as septic shock and meningitis. To study this crucial type of infection, its specific environment...

Mutational Analysis of Deinococcus radiodurans Bacteriophytochrome Reveals Key Amino Acids Necessary for the Photochromicity and Proton Exchange Cycle of Phytochromes*S⃞

Wagner, Jeremiah R., Zhang, Junrui, Von Stetten, David, Günther, Mina, Murgida, Daniel H., Mroginski, Maria Andrea, ...

The ability of phytochromes (Phy) to act as photointerconvertible light switches in plants and microorganisms depends on key interactions between the bilin chromophore and the apoprotein that promote...

T-Cell Responses to the Trypanosome Variant Surface Glycoprotein Are Not Limited to Hypervariable Subregions▿

Dagenais, Taylor R., Demick, Karen P., Bangs, James D., Forest, Katrina T., Paulnock, Donna M., Mansfield, John M.

Variable subregions within the variant surface glycoprotein (VSG) coat displayed by African trypanosomes are predicted sites for T- and B-cell recognition. Hypervariable subregion 1 (HV-1) is...