Wnt signaling induces epithelial differentiation during cutaneous wound healing (2006)
Fathke, Carrie, Wilson, Lynne, Shah, Kavita, Kim, Brian, Hocking, Anne, Moon, Randall, ...
Abstract Background Cutaneous wound repair in adult mammals does not regenerate the original epithelial architecture and results in altered skin function. We propose that lack of regeneration may be...
Article Computer Simulations Improve University Instructional Laboratories 1 (2004)
Nicola J. Gibbons, Chris Evans, Annette Payne, Kavita Shah
Laboratory classes are commonplace and essential in biology departments but can sometimes be cumbersome, unreliable, and a drain on time and resources. As university intakes increase, pressure on...
Shah, Kavita, Liu, Yi, Deirmengian, Carl, Shokat, Kevan M.
Protein phosphorylation plays a central role in controlling many diverse signal transduction pathways in all cells. Novel protein kinases are identified at a rapid rate using homology cloning methods...
Provance, D. William, Gourley, Christopher R., Silan, Colleen M., Cameron, L. C., Shokat, Kevan M., Goldenring, James R., ...
Selective, in situ inhibition of individual unconventional myosins is a powerful approach to determine their specific physiological functions. Here, we report the engineering of a myosin Vb mutant...
Computer Simulations Improve University Instructional Laboratories1
Gibbons, Nicola J., Evans, Chris, Payne, Annette, Shah, Kavita, Griffin, Darren K.
Laboratory classes are commonplace and essential in biology departments but can sometimes be cumbersome, unreliable, and a drain on time and resources. As university intakes increase, pressure on...
The vast complexity of platelet-derived growth factor (PDGF)-induced downstream signaling pathways is well known, but the precise roles of critical players still elude us due to our lack of specific...
A Chemical-Genetic Strategy Implicates Myosin-1c in Adaptation by Hair Cells
Holt, Jeffrey R., Gillespie, Susan K.H., Provance, D. William, Shah, Kavita, Shokat, Kevan M., Corey, David P., ...
Myosin-1c (also known as myosin-Iβ) has been proposed to mediate the slow component of adaptation by hair cells, the sensory cells of the inner ear. To test this hypothesis, we mutated tyrosine-61...
Wnt signaling induces epithelial differentiation during cutaneous wound healing
Fathke, Carrie, Wilson, Lynne, Shah, Kavita, Kim, Brian, Hocking, Anne, Moon, Randall, ...
Shah, Kavita, Liu, Yi, Deirmengian, Carl, Shokat, Kevan M.
Protein phosphorylation plays a central role in controlling many diverse signal transduction pathways in all cells. Novel protein kinases are identified at a rapid rate using homology cloning methods...
Provance, D. William, Gourley, Christopher R., Silan, Colleen M., Cameron, L. C., Shokat, Kevan M., Goldenring, James R., ...
Selective, in situ inhibition of individual unconventional myosins is a powerful approach to determine their specific physiological functions. Here, we report the engineering of a myosin Vb mutant...
Computer Simulations Improve University Instructional Laboratories1
Gibbons, Nicola J., Evans, Chris, Payne, Annette, Shah, Kavita, Griffin, Darren K.
Laboratory classes are commonplace and essential in biology departments but can sometimes be cumbersome, unreliable, and a drain on time and resources. As university intakes increase, pressure on...
The vast complexity of platelet-derived growth factor (PDGF)-induced downstream signaling pathways is well known, but the precise roles of critical players still elude us due to our lack of specific...
Wnt signaling induces epithelial differentiation during cutaneous wound healing
Fathke, Carrie, Wilson, Lynne, Shah, Kavita, Kim, Brian, Hocking, Anne, Moon, Randall, ...
c-Abl phosphorylates Dok1 to promote filopodia during cell spreading
Woodring, Pamela J., Meisenhelder, Jill, Johnson, Sam A., Zhou, Guo-Lei, Field, Jeffrey, Shah, Kavita, ...
Filopodia are dynamic F-actin structures that cells use to explore their environment. c-Abl tyrosine kinase promotes filopodia during cell spreading through an unknown mechanism that does not require...
Novel Genetic Tools Reveal Cdk5's Major Role in Golgi Fragmentation in Alzheimer's Disease
Sun, Kai-Hui, De Pablo, Yolanda, Vincent, Fabien, Johnson, Emmanuel O., Chavers, Angela K., Shah, Kavita
Golgi fragmentation is a common feature in multiple neurodegenerative diseases; however, the precise mechanism that causes fragmentation remains obscure. A potential link between Cdk5 and Golgi...