Kay Nieselt

Prequips--an extensible software platform for integration, visualization and analysis of LC-MS/MS proteomics data (2009)

Gehlenborg, Nils, Yan, Wei, Lee, Inyoul Y., Yoo, Hyuntae, Nieselt, Kay, Hwang, Daehee, ...

Summary: We describe an integrative software platform, Prequips, for comparative proteomics-based systems biology analysis that: (i) integrates all information generated from mass spectrometry...

BIOINFORMATICSAPPLICATIONSNOTE Mayday- a microarray data analysis workbench (2008)

Janko Dietzsch, Nils Gehlenborg, Kay Nieselt

Mayday is a workbench for visualization, analysis and storage of microarray data. It features a graphical user interface and supports the development and integration of existing and new analysis...

GeneMining in Mayday, a feature selection framework for binary classification (2008)

Stephan Symons, Christian Schillinger, Janko Dietzsch, Florian Battke, Kay Nieselt

The microarray technology has become a standard method for broad scale gene expression analysis. With increasingly large array and experiment designs, data analysis software must keep pace with this...

Comparative Analysis of Structured RNAs in S. cerevisiae Indicates a Multitude of Different Functions (2008)

Stephan Steigele, Wolfgang Huber, Claudia Fried, Peter F. Stadler, Kay Nieselt

Background: Non-coding RNAs (ncRNAs) are in emerging focus for both computational analysis and experimental research resulting in a growing number of novel, non-protein coding transcripts with often...

Comparative analysis of structured RNAs in S. cerevisiaeindicates a multitude of different functions (2007)

Steigele, Stephan, Huber, Wolfgang, Stocsits, Claudia, Stadler, Peter F, Nieselt, Kay

Abstract Background Non-coding RNAs (ncRNAs) are an emerging focus for both computational analysis and experimental research, resulting in a growing number of novel, non-protein coding transcripts...

On the maximal cliques in c-max-tolerance graphs and their application in clustering molecular sequences (2006)

Lehmann, Katharina A, Kaufmann, Michael, Steigele, Stephan, Nieselt, Kay

Abstract Given a set S of n locally aligned sequences, it is a needed prerequisite to partition it into groups of very similar sequences to facilitate subsequent computations, such as the generation...

Functional evaluation of domain-domain interactions and human protein interaction networks (2006)

Schlicker, Andreas, Huthmacher, Carola, Ramírez, Fidel, Lengauer, Thomas, Albrecht, Mario, Huson, Daniel, ...

Large amounts of protein and domain interaction data are being produced by experimental high-throughput techniques and computational approaches. To gain insight into the value of the provided data,...

Mayday-a microarray data analysis workbench (2006)

Dietzsch, Janko, Gehlenborg, Nils, Nieselt, Kay

Mayday is a workbench for visualization, analysis and storage of microarray data. It features a graphical user interface and supports the development and integration of existing and new analysis...

Gene expression Mayday-a microarray data analysis workbench (2005)

Janko Dietzsch, Nils Gehlenborg, Kay Nieselt

Mayday is a workbench for visualization, analysis and storage of microarray data. It features a graphical user interface and supports the development and integration of existing and new analysis...

Open reading frames provide a rich pool of potential natural antisense transcripts in fungal genomes (2005)

Steigele, Stephan, Nieselt, Kay

Natural antisense transcripts are reported from all kingdoms of life and several recent reports of genomewide screens indicate that they are widely distributed. These transcripts seem to be involved...

DIALIGN P: Fast pair-wise and multiple sequence alignment using parallel processors (2004)

Schmollinger, Martin, Nieselt, Kay, Kaufmann, Michael, Morgenstern, Burkhard

Abstract Background Parallel computing is frequently used to speed up computationally expensive tasks in Bioinformatics. Results Herein, a parallel version of the multi-alignment program DIALIGN is...

BioMed Central (2004)

Bmc Bioinformatics, Martin Schmollinger, Kay Nieselt, Michael Kaufmann, Burkhard Morgenstern, Michael Kaufmann, ...

Software DIALIGN P: Fast pair-wise and multiple sequence alignment using parallel processors

Open reading frames provide a rich pool of potential natural antisense transcripts in fungal genomes

Steigele, Stephan, Nieselt, Kay

Natural antisense transcripts are reported from all kingdoms of life and several recent reports of genomewide screens indicate that they are widely distributed. These transcripts seem to be involved...

On the maximal cliques in c-max-tolerance graphs and their application in clustering molecular sequences

Lehmann, Katharina A, Kaufmann, Michael, Steigele, Stephan, Nieselt, Kay

Given a set S of n locally aligned sequences, it is a needed prerequisite to partition it into groups of very similar sequences to facilitate subsequent computations, such as the generation of a...

Open reading frames provide a rich pool of potential natural antisense transcripts in fungal genomes

Steigele, Stephan, Nieselt, Kay

Natural antisense transcripts are reported from all kingdoms of life and several recent reports of genomewide screens indicate that they are widely distributed. These transcripts seem to be involved...

On the maximal cliques in c-max-tolerance graphs and their application in clustering molecular sequences

Lehmann, Katharina A, Kaufmann, Michael, Steigele, Stephan, Nieselt, Kay

Given a set S of n locally aligned sequences, it is a needed prerequisite to partition it into groups of very similar sequences to facilitate subsequent computations, such as the generation of a...

Chromatin modifications induced by PML-RARα repress critical targets in leukemogenesis as analyzed by ChIP-Chip

Hoemme, Claudia, Peerzada, Abdul, Behre, Gerhard, Wang, Yipeng, McClelland, Michael, Nieselt, Kay, ...

The translocation t(15;17) generates the chimeric PML-RARα transcription factor that is the initiating event of acute promyelocytic leukemia. A global view of PML-RARα transcriptional functions was...