Kazuhiro Nouso

A case of hepatocellular carcinoma with skin injury of the upper abdominal wall after transcatheter arterial chemoembolization: a case report (2009)

Kanzaki, Hiromitsu, Nouso, Kazuhiro, Miyahara, Koji, Kajikawa, Naoko, Kobayashi, Sayo, Sakakihara, Ichiro, ...

Abstract Introduction Transcatheter arterial chemoembolization has been widely used to treat advanced hepatocellular carcinoma that cannot be treated by local ablation therapies or surgical...

Twist expression promotes migration and invasion in hepatocellular carcinoma (2009)

Matsuo, Noriyuki, Shiraha, Hidenori, Fujikawa, Tatsuya, Takaoka, Nobuyuki, Ueda, Naoki, Tanaka, Shigetomi, ...

Abstract Background Twist, a transcription factor of the basic helix-loop-helix class, is reported to regulate cancer metastasis. It is known to induce epithelial-mesenchymal transition (EMT). In...

Immunohistochemical studies of PIVKA-II in hepatocellular carcinoma by indirect immunofluorescence (2007)

Kuwahara, Naoaki, Higashi, Toshihiro, Nouso, Kazuhiro, Ito, Toshio, Tsuji, Takao

Tissue PIVKA-II was examined in 32 hepatocellular carcinomas and 2 metastatic liver tumors using indirect immunofluorescence, and the results were compared with the size, histological grading and...

Cathepsin B in the Growth of Colorectal Cancer: Increased Activity of Cathepsin B in Human Colorectal Cancer (2007)

Satoh, Yasumasa, Higashi, Toshihiro, Nouso, Kazuhiro, Shiota, Tetsuya, Kinugasa, Nobuyuki, Yoshida, Keigo, ...

Cathepsin B, a thiol protease, is involved in cancer metastasis. To clarify the role of cathepsin B in tumor progression in human colorectal cancer, the relationship between its activity,...

Cathepsin B in the Growth of Colorectal Cancer: Suppressive Effect of Leupeptin on the Growth of DMH-Induced Rat Colon Neoplasm (2007)

Satoh, Yasumasa, Higashi, Toshihiro, Nouso, Kazuhiro, Shiota, Tetsuya, Kinugasa, Nobuyuki, Yoshida, Keigo, ...

Cathepsin B, a thiol protease, has been reported to be involved in cancer progression and metastasis. The suppressive effects of two kinds of protease inhibitors, leupeptin and dietary camostate...

Usefulness of indocyanine green injection during ultrasound-guided liver biopsy for the diagnosis of small hepatocellular carcinoma. (2007)

Kimura, Yoshihiro, Higashi, Toshihiro, Kuwahara, Naoaki, Nouso, Kazuhiro, Ohguchi, Shouhei, Hino, Naoki, ...

To diagnose hepatocellular carcinoma (HCC) functionally and immediately, we examined the usefulness of indocyanine green (ICG) injection during ultrasound-guided liver biopsy. Liver specimens were...

Recombinant mouse cytochromes P1-450 and P3-450: enzymatic characterization of the hemoprotein expressed in human cells infected with recombinant vaccinia virus. (2007)

Nouso, Kazuhiro, Battula, Narayama, Thorgeirsson, Snorri S, Higashi, Toshihiro, Tsuji, Takao

We expressed mouse cytochrome P1-450 and P3-450 using recombinant vaccinia virus gene expression system in HeLa cells that were devoid of significant basal levels of P-450. HeLa cells were infected...

Ultrasonographic characteristics of small hepatocellular carcinoma. (2007)

Higashi, Toshihiro, Tobe, Kazuo, Asano, Ken-ichiro, Ikeda, Hiroshi, Ohsawa, Toshiya, Iwasaki, Yoshiaki, ...

The ultrasonographic characteristics of hepatocellular carcinomas (HCC) were investigated. Four typical features of HCCs, "mosaic internal echo pattern", "halo", "lateral shadow" and "posterior echo...

Hepatitis C virus quasispecies in cancerous and noncancerous hepatic lesions: the core protein-encoding region. (2006)

Alam, Shahjalal S., Nakamura, Takashi, Naganuma, Atsushi, Nozaki, Akito, Nouso, Kazuhiro, Shimomura, Hiroyuki, ...

We have shown that highly proofreading DNA polymerase is required for the polymerase chain reaction in the genetic analysis of hepatitis C virus (HCV). To clarify the status of HCV quasispecies in...

Effects of zinc deficiency/zinc supplementation on ammonia metabolism in patients with decompensated liver cirrhosis. (2006)

Yoshida, Yasuhiro, Higashi, Toshihiro, Nouso, Kazuhiro, Nakatsukasa, Harushige, Nakamura, Shin-ichiro, Watanabe, Akiharu, ...

Hepatic encephalopathy is one of the major complications in decompensated liver cirrhosis. The current study was conducted to clarify the mechanisms of zinc deficiency in liver cirrhosis and its...

Functional promoter upstream p53 regulatory sequence of IGFBP3that is silenced by tumor specific methylation (2005)

Hanafusa, Tadashi, Shinji, Toshiyuki, Shiraha, Hidenori, Nouso, Kazuhiro, Iwasaki, Yoshiaki, Yumoto, Eichiro, ...

Abstract Background Insulin-like growth factor binding protein (IGFBP)-3 functions as a carrier of insulin-like growth factors (IGFs) in circulation and a mediator of the growth suppression signal in...

Functional promoter upstream p53 regulatory sequence of IGFBP3 (2004)

Hanafusa, Tadashi, Shinji, Toshiyuki, Shiraha, Hidenori, Nouso, Kazuhiro, Iwasaki, Yoshiaki, Yumoto, Eichiro, ...

Background: Insulin-like growth factor binding protein (IGFBP)-3 functions as a carrier of insulinlike growth factors (IGFs) in circulation and a mediator of the growth suppression signal in cells....

Functional promoter upstream p53 regulatory sequence of IGFBP3 (2004)

Hanafusa, Tadashi, Shinji, Toshiyuki, Shiraha, Hidenori, Nouso, Kazuhiro, Iwasaki, Yoshiaki, Yumoto, Eichiro, ...

Background: Insulin-like growth factor binding protein (IGFBP)-3 functions as a carrier of insulinlike growth factors (IGFs) in circulation and a mediator of the growth suppression signal in cells....