BIOINFORMATICS ORIGINAL PAPER (2008)
Genome Analysis, Noriyuki Kitagawa, Takanori Washio, Shunichi Kosugi, Tomoya Yamashita, Kenji Higashi, ...
Vol. 21 no. 9 2005, pages 1758–1763 doi:10.1093/bioinformatics/bti253 Computational analysis suggests that alternative first exons are involved in tissue-specific transcription in rice (Oryza...
Kitagawa, Noriyuki, Washio, Takanori, Kosugi, Shunichi, Yamashita, Tomoya, Higashi, Kenji, Yanagawa, Hiroshi, ...
Motivation: Transcription start site selection and alternative splicing greatly contribute to diversifying gene expression. Recent studies have revealed the existence of alternative first exons, but...
Kitagawa, Noriyuki, Washio, Takanori, Kosugi, Shunichi, Yamashita, Tomoya, Higashi, Kenji, Yanagawa, Hiroshi, ...
Motivation: Transcription start site selection and alternative splicing greatly contribute to diversifying gene expression. Recent studies have revealed the existence of alternative first exons, but...
Nagata, Toshifumi, Iizumi, Shigemi, Sato, Kouji, Ooka, Hisako, Kawai, Jun, Carninci, Piero, ...
We obtained 32K full-length cDNA sequence data from the rice full-length cDNA project and performed a homology search against NCBI GenBank data. We have also searched homologs of Arabidopsis and...
Nagata, Toshifumi, Iizumi, Shigemi, Satoh, Kouji, Ooka, Hisako, Kawai, Jun, Carninci, Piero, ...
We obtained 32K full-length cDNA sequence data from the rice full-length cDNA project and performed a homology search against NCBI GenBank data. We have also searched homologs of Arabidopsis and...
Nagata, Toshifumi, Iizumi, Shigemi, Satoh, Kouji, Ooka, Hisako, Kawai, Jun, Carninci, Piero, ...
We obtained 32K full-length cDNA sequence data from the rice full-length cDNA project and performed a homology search against NCBI GenBank data. We have also searched homologs of Arabidopsis and...
Nagata, Toshifumi, Iizumi, Shigemi, Sato, Kouji, Ooka, Hisako, Kawai, Jun, Carninci, Piero, ...
We obtained 32K full-length cDNA sequence data from the rice full-length cDNA project and performed a homology search against NCBI GenBank data. We have also searched homologs of Arabidopsis and...
Nagata, Toshifumi, Iizumi, Shigemi, Satoh, Kouji, Ooka, Hisako, Kawai, Jun, Carninci, Piero, ...
We obtained 32K full-length cDNA sequence data from the rice full-length cDNA project and performed a homology search against NCBI GenBank data. We have also searched homologs of Arabidopsis and...
Antisense transcripts with rice full-length cDNAs (2003)
Osato, Naoki, Yamada, Hitomi, Satoh, Kouji, Ooka, Hisako, Yamamoto, Makoto, Suzuki, Kohji, ...
Abstract Background Natural antisense transcripts control gene expression through post-transcriptional gene silencing by annealing to the complementary sequence of the sense transcript. Because many...
Comprehensive Analysis of NAC Family Genes in Oryza sativa and Arabidopsis thaliana (2003)
Ooka, Hisako, Satoh, Kouji, Doi, Koji, Nagata, Toshifumi, Otomo, Yasuhiro, Murakami, Kazuo, ...
The NAC domain was originally characterized from consensus sequences from petunia NAM and from Arabidopsis ATAF1, ATAF2, and CUC2. Genes containing the NAC domain (NAC family genes) are plant...
Genomics Approach to Abscisic Acid- and Gibberellin-responsive Genes in Rice (2003)
Yazaki, Junshi, Kishimoto, Naoki, Nagata, Yuko, Ishikawa, Masahiro, Fujii, Fumiko, Hashimoto, Akiko, ...
We used an 8987-EST collection to construct a cDNA microarray system with various genomics information (full-length cDNA, expression profile, high accuracy genome sequence, phenotype, genetic map,...
Wavelet profiles: Their application in Oryza sativa DNA sequence analysis (2002)
Nobuyuki Kawagashira, Yasuhiro Ohtomo, Kazuo Murakami, Kenichi Matsubara, Jun Kawai, Piero Carninci, ...
Here we introduce our application of the wavelet analysis method to DNA sequences. In the signal processing field, Fourier transform is popular for analyzing wave data. However, although this method...
Kasai, Kazuo, Shin, Hye-Won, Shinotsuka, Chisa, Murakami, Kazuo, Nakayamat, Kazuhisa
Dynamins are a family of {small tilde}100-kDa GTPases that are thought to play a pivotal role in the formation of endocytic coated vesicles. There are three dynamin genes in mammals: dynamin I is...
Shin, Hye-Won, Shinotsuka, Chisa, Torii, Seiji, Murakami, Kazuo, Nakayama, Kazuhisa
The dynamin family of GTP-binding proteins are implicated in vesicular transport. These include mammalian dynamins I, II, III, and yeast Vps1p and Dnm1p. Dynamin is involved in the formation of...
Hosaka, Masahiro, Toda, Kyoko, Takatsu, Hiroyuki, Torii, Seiji, Murakami, Kazuo, Nakayama, Kazuhisa
ADP-ribosylation factors (ARFs) are a family of small GTP-binding proteins that are proposed to be involved in the formation of coated transport vesicles. Although six ARF sequences have been...
Expression of BMP-2,4 Genes during Early Development in Xenopus (1995)
Toshiyuki Yamagishi, Shin-ichiro Nishimatsu, Shintaro Nomura, Makoto Asashima, Kazuo Murakami, Naoto Ueno
The transforming growth factor-β (TGF-β) family has been implicated in the regulation of cell differentiation during early development. Bone morphogenetic proteins (BMPs) are thought to play...
Takahashi, Senye, Hatsuzawa, Kiyotaka, Watanabe, Toshio, Murakami, Kazuo, Nakayama, Kazuhisa
We have recently presented some sequence rules that govern the endoproteolytic processing of precursor proteins within the constitutive secretory pathway [Watanabe, T. et al. (1992) J. BioL Chem....
Nakagawa, Tsutomu, Hosaka, Masahiro, Torii, Seiji, Watanabe, Toshio, Murakami, Kazuo, Nakayama, Kazuhisa
We used the polymerase chain reaction to identify a mouse cDNA which represented a new member of a growing class of mammalian endoproteases homologous to the yeast Kex2 protease involved in the...
Comparative study of renin expression in the coagulating glands of C57BL/6 and Balb/c mice (1992)
KON, YASUHIRO, ENDOH, DAIJI, FUKAMIZU, AKIYOSHI, MURAKAMI, KAZUO, HASHIMOTO, YOSHIHARU, SUGIMURA, MAKOTO, ...
The comparative localisation of renin in the genital organs, especially in the coagulating glands of male mice of the strains C57BL/6 and Balb/c, was investigated using immunocytochemical,...
Comparative study of renin expression in the coagulating glands of C57BL/6 and Balb/c mice (1992)
KON, YASUHIRO, ENDOH, DAIJI, FUKAMIZU, AKIYOSHI, MURAKAMI, KAZUO, HASHIMOTO, YOSHIHARU, SUGIMURA, MAKOTO
The comparative localisation of renin in the genital organs, especially in the coagulating glands of male mice of the strains C57BL/6 and Balb/c, was investigated using immunocytochemical,...
Comparative study of renin expression in the coagulating glands of C57BL/6 and Balb/c mice (1992)
KON, YASUHIRO, ENDOH, DAIJI, FUKAMIZU, AKIYOSHI, MURAKAMI, KAZUO, HASHIMOTO, YOSHIHARU, SUGIMURA, MAKOTO
The comparative localisation of renin in the genital organs, especially in the coagulating glands of male mice of the strains C57BL/6 and Balb/c, was investigated using immunocytochemical,...
Tarnura, Kouichi, Tanimoto, Keiji, Murakami, Kazuo, Fukamizu, Akiyoshi
Renin, a key enzyme controlling blood pressure, is produced mainly in the kidney. To identify the transcriptional regulatory elements of the mouse Ren-1c gene, the promoter regions were fused to the...
Hatsuzawa, Kiyotaka, Murakami, Kazuo, Nakayama, Kazuhisa
We have recently shown that furin, a mammalian homologue of the yeast precursor-processing endoprotease Kex2, is involved in precursor cleavage at sites marked by the Arg-X-Lys/Arg-Arg motif...
Nakayama, Kazuhisa, Hosaka, Masahiro, Hatsuzawa, Kiyotaka, Murakami, Kazuo
We cloned and sequenced a cDNA from a library of mouse pituitary AtT-20 cells which are known to cleave an endogenous and various foreign prohormones at dibasic sites. This cDNA encodes a novel...
Identification of the Active Site of Human Renin with Use of New Fluorogenic Peptides (1991)
Nakamura, Nobuko, Satomura, Shinji, Matsuura, Shuji, Murakami, Kazuo
Fluorogenic peptide substrates were synthesized in which amino acid residues corresponded to the C-terminal and the N-terminal sides of the site of human angiotensinogen cleaved by renin. Compared...
Nagahama, Masami, Ikemizu, Jo, Misumi, Yoshio, Ikehara, Yukio, Murakami, Kazuo, Nakayama, Kazuhisa
It is well known that precursor cleavage at paired basic amino acids (e.g., Lys-Arg, Arg-Arg) within the regulated secretory pathway is one of the key steps to produce bioactive peptides. On the...
Yamauchi, Takeshi, Nagahama, Masami, Watanabe, Toshio, Ishizuka, Yasuyuki, Hori, Hitoshi, Murakami, Kazuo
Human prorenin is an inactive zymogen comprising 43 amino acid residues at the amino terminus of human renin. The aim of this work was to determine why prorenin is inactive at neutral pH. Eighteen...
Ishizuka, Yasuyuki, Iizumi, Shinji, Akiyama, Fumiaki, Hori, Hitoshi, Poorman, Roger A., Lobl, Tomas J., ...
Monoclonal antibodies were raised against a synthetic peptide (43 amino acid residues) that corresponds to the complete profragment of human prorenin. Seven monoclonal antibodies were chosen for...
Mouse spleen derived cDNA clones containing per repeat sequence (1988)
Nishimatsu, Shin-ichiro, Murakami, Kazuo, Mitsui, Youji, Ishida, Norio
KON, Yasuhiro, HASHIMOTO, Yoshiharu, KITAGAWA, Hiroshi, KUDO, Norio, MURAKAMI, Kazuo
Intrarenal distribution of renin-cotaining cells in 13 mammals and 2 fowls was immunohistochemically demonstrated. The immunoreactive cells were found as swollen epithelioid cells localized in...
Synthesis and Characterization of Human Prorenin in Escherichia coli (1986)
IMAI, Takashi, CHO, Takeshi, TAKAMATSU, Hiroyuki, HORI, Hitoshi, SAITO, Michiya, MASUDA, Tsutomu, ...
DNA sequences encoding Ile-Glu-Gly-Arg and human prorenin were joined and placed under the transcriptional control of the Escherichia coli trp promoter-operator in the expression vector pTR501. E....
Activation of Kidney Prorenin by Kidney Cathepsin B Isozymes (1982)
TAKAHASHI, Saori, MURAKAMI, Kazuo, MIYAKE, Yoshihiro
Kidney prorenin was converted to a form of active renin by kidney cathepsin B isozymes. The three isozymes showed similar catalytic behavior for prorenin. The optimal pH for the activation was in the...
SUZUKI, Fumiaki, NAKAMURA, Yukio, NAGATA, Yukio, OHSAWA, Tamiko, MURAKAMI, Kazuo
A pressor enzyme, renin, was purified about 60-fold by chromatography on an affinity column including pepstatin-aminohexyl-agarose with a high yield of 83% from the homogenate of adult mouse...
Purification and Characterization of Porcine Kidney Cathepsin B (1981)
TAKAHASHI, Saori, MURAKAMI, Kazuo, MIYAKE, Yoshihiro
Three types of cathepsin B were purified from porcine kidney by a procedure involving ammonium sulfate fractionation, acetone fractionation, pH-gradient elution from CM-cellulose, gel filtration,...
Antisense transcripts with rice full-length cDNAs
Osato, Naoki, Yamada, Hitomi, Satoh, Kouji, Ooka, Hisako, Yamamoto, Makoto, Suzuki, Kohji, ...
In this study, 687 sense-antisense transcript pairs from 32,127 full-length rice cDNA sequences were identified by aligning the cDNA sequences with rice genome sequences. The large number of pairs...
Angiotensin II plays a pathogenic role in immune-mediated renal injury in mice
Hisada, Yutaka, Sugaya, Takeshi, Yamanouchi, Masaya, Uchida, Hiromi, Fujimura, Hisako, Sakurai, Hiroaki, ...
Several lines of evidence show the importance of angiotensin II (AII) in renal injuries, especially when hemodynamic abnormalities are involved. To elucidate the role of AII in immune-mediated renal...
Antisense transcripts with rice full-length cDNAs
Osato, Naoki, Yamada, Hitomi, Satoh, Kouji, Ooka, Hisako, Yamamoto, Makoto, Suzuki, Kohji, ...
In this study, 687 sense-antisense transcript pairs from 32,127 full-length rice cDNA sequences were identified by aligning the cDNA sequences with rice genome sequences. The large number of pairs...
Angiotensin II plays a pathogenic role in immune-mediated renal injury in mice
Hisada, Yutaka, Sugaya, Takeshi, Yamanouchi, Masaya, Uchida, Hiromi, Fujimura, Hisako, Sakurai, Hiroaki, ...
Several lines of evidence show the importance of angiotensin II (AII) in renal injuries, especially when hemodynamic abnormalities are involved. To elucidate the role of AII in immune-mediated renal...
Satoh, Kouji, Doi, Koji, Nagata, Toshifumi, Kishimoto, Naoki, Suzuki, Kohji, Otomo, Yasuhiro, ...
Rice (Oryza sativa L.) is a model organism for the functional genomics of monocotyledonous plants since the genome size is considerably smaller than those of other monocotyledonous plants. Although...