Hao, Ke, Chudin, Eugene, McElwee, Joshua, Schadt, Eric E
Abstract Background Although high-throughput genotyping arrays have made whole-genome association studies (WGAS) feasible, only a small proportion of SNPs in the human genome are actually surveyed in...
Mapping the Genetic Architecture of Gene Expression in Human Liver (2008)
Eric E. Schadt, Cliona Molony, Eugene Chudin, Ke Hao, Xia Yang, Pek Y. Lum, ...
Genetic variants that are associated with common human diseases do not lead directly to disease, but instead act on intermediate, molecular phenotypes that in turn induce changes in higher-order...
Rameen Beroukhim, Ming Lin, Yuhyun Park, Ke Hao, Xiaojun Zhao, Levi A. Garraway, ...
Loss of heterozygosity (LOH) of chromosomal regions bearing tumor suppressors is a key event in the evolution of epithelial and mesenchymal tumors. Identification of these regions usually relies on...
Rameen Beroukhim, Ming Lin, Yuhyun Park, Ke Hao, Xiaojun Zhao, Levi Alec Garraway, ...
Loss of heterozygosity (LOH) of chromosomal regions bearing tumor suppressors is a key event in the evolution of epithelial and mesenchymal tumors. Identification of these regions usually relies on...
Comparative linkage analysis and visualization of high-density oligonucleotide SNP array data (2005)
Leykin, Igor, Hao, Ke, Cheng, Junsheng, Meyer, Nicole, Pollak, Martin R, Smith, Richard JH, ...
Abstract Background The identification of disease-associated genes using single nucleotide polymorphisms (SNPs) has been increasingly reported. In particular, the Affymetrix Mapping 10 K SNP...
Hao, Ke, Wang, Xiaobin, Niu, Tianhua, Xu, Xin, Li, Ang, Chang, Weili, ...
Preterm delivery (PTD) is the leading cause of infant mortality and morbidity worldwide. The etiology of PTD is largely unknown but is believed to be complex, encompassing multiple genetic and...
Hao, Ke, Wang, Xiaobin, Niu, Tianhua, Xu, Xin, Li, Ang, Chang, Weili, ...
Preterm delivery (PTD) is the leading cause of infant mortality and morbidity worldwide. The etiology of PTD is largely unknown but is believed to be complex, encompassing multiple genetic and...
Hao, Ke, Wang, Xiaobin, Niu, Tianhua, Xu, Xin, Li, Ang, Chang, Weili, ...
Preterm delivery (PTD) is the leading cause of infant mortality and morbidity worldwide. The etiology of PTD is largely unknown but is believed to be complex, encompassing multiple genetic and...
Comparative linkage analysis and visualization of high-density oligonucleotide SNP array data
Leykin, Igor, Hao, Ke, Cheng, Junsheng, Meyer, Nicole, Pollak, Martin R, Smith, Richard JH, ...
Inferring Loss-of-Heterozygosity from Unpaired Tumors Using High-Density Oligonucleotide SNP Arrays
Beroukhim, Rameen, Lin, Ming, Park, Yuhyun, Hao, Ke, Zhao, Xiaojun, Garraway, Levi A, ...
Loss of heterozygosity (LOH) of chromosomal regions bearing tumor suppressors is a key event in the evolution of epithelial and mesenchymal tumors. Identification of these regions usually relies on...
Comparative linkage analysis and visualization of high-density oligonucleotide SNP array data
Leykin, Igor, Hao, Ke, Cheng, Junsheng, Meyer, Nicole, Pollak, Martin R, Smith, Richard JH, ...
Inferring Loss-of-Heterozygosity from Unpaired Tumors Using High-Density Oligonucleotide SNP Arrays
Beroukhim, Rameen, Lin, Ming, Park, Yuhyun, Hao, Ke, Zhao, Xiaojun, Garraway, Levi A, ...
Loss of heterozygosity (LOH) of chromosomal regions bearing tumor suppressors is a key event in the evolution of epithelial and mesenchymal tumors. Identification of these regions usually relies on...
Mapping the Genetic Architecture of Gene Expression in Human Liver
Schadt, Eric E, Molony, Cliona, Chudin, Eugene, Hao, Ke, Yang, Xia, Lum, Pek Y, ...
Genetic variants that are associated with common human diseases do not lead directly to disease, but instead act on intermediate, molecular phenotypes that in turn induce changes in higher-order...
Calibrating the Performance of SNP Arrays for Whole-Genome Association Studies
Hao, Ke, Schadt, Eric E., Storey, John D.
To facilitate whole-genome association studies (WGAS), several high-density SNP genotyping arrays have been developed. Genetic coverage and statistical power are the primary benchmark metrics in...