Ke Hu

Organizational Changes of the Daughter Basal Complex during the Parasite Replication of Toxoplasma gondii (2008)

Ke Hu

The apicomplexans are a large group of parasitic protozoa, many of which are important human and animal pathogens, including Plasmodium falciparum and Toxoplasma gondii. These parasites cause disease...

Hepatitis C virus cell-cell transmission in hepatoma cells in the presence of neutralizing antibodies (2008)

Timpe, Jennifer M., Stamataki, Zania, Jennings, Adam, Hu, Ke, Farquhar, Michelle J., Harris, Helen J., ...

Hepatitis C virus (HCV) infection of Huh-7.5 hepatoma cells results in focal areas of infection where transmission is potentiated by cell-cell contact. To define route(s) of transmission, HCV was...

Cytoskeletal Components of an Invasion Machine—The Apical Complex of Toxoplasma gondii (2006)

Ke Hu, Jeff Johnson, Laurence Florens, Martin Fraunholz, Sapna Suravajjala, Camille DiLullo, ...

The apical complex of Toxoplasma gondii is widely believed to serve essential functions in both invasion of its host cells (including human cells), and in replication of the parasite. The...

Building a parasite: The study of the cell division and cytoskeleton of Toxoplasma gondii (2002)

Hu, Ke

Toxoplasma gondii and other members of the phylum Apicomplexa divide by assembling daughters within the mother on a scaffold consisting of cytoskeletal elements and flattened membrane vesicles....

Daughter Cell Assembly in the Protozoan Parasite Toxoplasma gondii

Hu, Ke, Mann, Tara, Striepen, Boris, Beckers, Con J. M., Roos, David S., Murray, John M.

The phylum Apicomplexa includes thousands of species of obligate intracellular parasites, many of which are significant human and/or animal pathogens. Parasites in this phylum replicate by assembling...

Measuring tubulin content in Toxoplasma gondii: A comparison of laser-scanning confocal and wide-field fluorescence microscopy

Swedlow, Jason R., Hu, Ke, Andrews, Paul D., Roos, David S., Murray, John M.

Toxoplasma gondii is an intracellular parasite that proliferates within most nucleated cells, an important human pathogen, and a model for the study of human and veterinary parasitic infections. We...

Cytoskeletal Components of an Invasion Machine—The Apical Complex of Toxoplasma gondii

Hu, Ke, Johnson, Jeff, Florens, Laurence, Fraunholz, Martin, Suravajjala, Sapna, DiLullo, Camille, ...

The apical complex of Toxoplasma gondii is widely believed to serve essential functions in both invasion of its host cells (including human cells), and in replication of the parasite. The...

Daughter Cell Assembly in the Protozoan Parasite Toxoplasma gondii

Hu, Ke, Mann, Tara, Striepen, Boris, Beckers, Con J. M., Roos, David S., Murray, John M.

The phylum Apicomplexa includes thousands of species of obligate intracellular parasites, many of which are significant human and/or animal pathogens. Parasites in this phylum replicate by assembling...

Measuring tubulin content in Toxoplasma gondii: A comparison of laser-scanning confocal and wide-field fluorescence microscopy

Swedlow, Jason R., Hu, Ke, Andrews, Paul D., Roos, David S., Murray, John M.

Toxoplasma gondii is an intracellular parasite that proliferates within most nucleated cells, an important human pathogen, and a model for the study of human and veterinary parasitic infections. We...

Cytoskeletal Components of an Invasion Machine—The Apical Complex of Toxoplasma gondii

Hu, Ke, Johnson, Jeff, Florens, Laurence, Fraunholz, Martin, Suravajjala, Sapna, DiLullo, Camille, ...

The apical complex of Toxoplasma gondii is widely believed to serve essential functions in both invasion of its host cells (including human cells), and in replication of the parasite. The...

Identification of PhIL1, a Novel Cytoskeletal Protein of the Toxoplasma gondii Pellicle, through Photosensitized Labeling with 5-[125I]Iodonaphthalene-1-Azide

Gilk, Stacey D., Raviv, Yossef, Hu, Ke, Murray, John M., Beckers, Con J. M., Ward, Gary E.

The pellicle of the protozoan parasite Toxoplasma gondii is a unique triple bilayer structure, consisting of the plasma membrane and two tightly apposed membranes of the underlying inner membrane...

Organizational Changes of the Daughter Basal Complex during the Parasite Replication of Toxoplasma gondii

Hu, Ke

The apicomplexans are a large group of parasitic protozoa, many of which are important human and animal pathogens, including Plasmodium falciparum and Toxoplasma gondii. These parasites cause disease...

Effect of Cell Polarization on Hepatitis C Virus Entry▿

Mee, Christopher J., Grove, Joe, Harris, Helen J., Hu, Ke, Balfe, Peter, McKeating, Jane A.

The primary reservoir for hepatitis C virus (HCV) replication in vivo is believed to be hepatocytes within the liver. Three host cell molecules have been reported to be important entry factors for...

A novel polymer of tubulin forms the conoid of Toxoplasma gondii

Hu, Ke, Roos, David S., Murray, John M.

Toxoplasma gondii is an obligatory intracellular parasite, an important human pathogen, and a convenient laboratory model for many other human and veterinary pathogens in the phylum Apicomplexa, such...

CD81 and Claudin 1 Coreceptor Association: Role in Hepatitis C Virus Entry▿ †

Harris, Helen J., Farquhar, Michelle J., Mee, Christopher J., Davis, Christopher, Reynolds, Gary M., Jennings, Adam, ...

Hepatitis C virus (HCV) is an enveloped positive-stranded RNA hepatotropic virus. HCV pseudoparticles infect liver-derived cells, supporting a model in which liver-specific molecules define HCV...

TgICMAP1 Is a Novel Microtubule Binding Protein in Toxoplasma gondii

Heaslip, Aoife T., Ems-McClung, Stephanie C., Hu, Ke

The microtubule cytoskeleton provides essential structural support for all eukaryotic cells and can be assembled into various higher order structures that perform drastically different functions....