Keiji Ogura

Reduction in Mutation Frequency by Very Low-Dose Gamma Irradiation of Drosophila melanogaster Germ Cells (2009)

Keiji Ogura, Junji Magae, Yasushi Kawakami, Takao Koana

Ogura, K., Magae, J., Kawakami, Y. and Koana, T. Reduction in Mutation Frequency by Very Low-Dose Gamma Irradiation of Drosophila melanogaster Germ Cells. Radiat. Res. 171, 1–8 (2009).To determine...

Oral bisphosphonate prevents bone loss in androgen deprivation therapy for nonmetastatic prostate cancer (2008)

Kawahara, Takashi, Kobayashi, Takashi, Nishizawa, Koji, Kobori, Go, Mitsumori, Kenji, Ogura, Keiji

We studied the short-term efficacy of alendronate, an oral bisphosphonates, on bone mineral density (BMD) during androgen deprivation therapy (ADT) in 45 nonmetastatic prostate cancer patients at the...

Rapid Detection of Mutations in the 23S rRNA Gene of Helicobacter pylori That Confers Resistance to Clarithromycin Treatment to the Bacterium

Matsumura, Masayuki, Hikiba, Yoko, Ogura, Keiji, Togo, Goichi, Tsukuda, Izumi, Ushikawa, Kenji, ...

We developed a new method capable of detecting point mutations in the 23S rRNA gene of Helicobacter pylori using a LightCycler. Our method can detect a mutation in this gene in less than 1 h and can...

Detection of Clarithromycin-Resistant Helicobacter pylori Strains by a Preferential Homoduplex Formation Assay

Maeda, Shin, Yoshida, Haruhiko, Matsunaga, Hironari, Ogura, Keiji, Kawamata, Osamu, Shiratori, Yasushi, ...

It has been shown that resistance to clarithromycin, a major cause of failure in Helicobacter pylori eradication therapy, is associated with point mutations in the 23S rRNA gene. We sought to apply...

Determination of Helicobacter pylori Virulence by Simple Gene Analysis of the cag Pathogenicity Island

Ikenoue, Tsuneo, Maeda, Shin, Ogura, Keiji, Akanuma, Masao, Mitsuno, Yuzo, Imai, Yasuo, ...

Nucleic acid amplification was performed for five loci in the cag pathogenicity island (PAI) of Helicobacter pylori (comprising cagA, the cagA promoter region, cagE, cagT, and the left end of cagII...

Helicobacter pylori Activates the Cyclin D1 Gene through Mitogen- Activated Protein Kinase Pathway in Gastric Cancer Cells

Hirata, Yoshihiro, Maeda, Shin, Mitsuno, Yuzo, Akanuma, Masao, Yamaji, Yutaka, Ogura, Keiji, ...

Helicobacter pylori induces cellular proliferation in host cells, but the mechanism remains unclear. Thus, we examined the effect of H. pylori on cyclin D1, an important regulator of the cell cycle,...

Helicobacter acinonychis: Genetic and Rodent Infection Studies of a Helicobacter pylori-Like Gastric Pathogen of Cheetahs and Other Big Cats

Dailidiene, Daiva, Dailide, Giedrius, Ogura, Keiji, Zhang, Maojun, Mukhopadhyay, Asish K., Eaton, Kathryn A., ...

Insights into bacterium-host interactions and genome evolution can emerge from comparisons among related species. Here we studied Helicobacter acinonychis (formerly H. acinonyx), a species closely...

Helicobacter pylori Induces IκB Kinase α Nuclear Translocation and Chemokine Production in Gastric Epithelial Cells

Hirata, Yoshihiro, Maeda, Shin, Ohmae, Tomoya, Shibata, Wataru, Yanai, Ayako, Ogura, Keiji, ...

NF-κB is an important transcriptional factor that is involved in multiple cellular responses, such as inflammation and antiapoptosis. IκB kinase α (IKKα) and IKKβ, which are critical regulators...

Rapid Detection of Mutations in the 23S rRNA Gene of Helicobacter pylori That Confers Resistance to Clarithromycin Treatment to the Bacterium

Matsumura, Masayuki, Hikiba, Yoko, Ogura, Keiji, Togo, Goichi, Tsukuda, Izumi, Ushikawa, Kenji, ...

We developed a new method capable of detecting point mutations in the 23S rRNA gene of Helicobacter pylori using a LightCycler. Our method can detect a mutation in this gene in less than 1 h and can...

Detection of Clarithromycin-Resistant Helicobacter pylori Strains by a Preferential Homoduplex Formation Assay

Maeda, Shin, Yoshida, Haruhiko, Matsunaga, Hironari, Ogura, Keiji, Kawamata, Osamu, Shiratori, Yasushi, ...

It has been shown that resistance to clarithromycin, a major cause of failure in Helicobacter pylori eradication therapy, is associated with point mutations in the 23S rRNA gene. We sought to apply...

Determination of Helicobacter pylori Virulence by Simple Gene Analysis of the cag Pathogenicity Island

Ikenoue, Tsuneo, Maeda, Shin, Ogura, Keiji, Akanuma, Masao, Mitsuno, Yuzo, Imai, Yasuo, ...

Nucleic acid amplification was performed for five loci in the cag pathogenicity island (PAI) of Helicobacter pylori (comprising cagA, the cagA promoter region, cagE, cagT, and the left end of cagII...

Helicobacter pylori Activates the Cyclin D1 Gene through Mitogen- Activated Protein Kinase Pathway in Gastric Cancer Cells

Hirata, Yoshihiro, Maeda, Shin, Mitsuno, Yuzo, Akanuma, Masao, Yamaji, Yutaka, Ogura, Keiji, ...

Helicobacter pylori induces cellular proliferation in host cells, but the mechanism remains unclear. Thus, we examined the effect of H. pylori on cyclin D1, an important regulator of the cell cycle,...

Helicobacter acinonychis: Genetic and Rodent Infection Studies of a Helicobacter pylori-Like Gastric Pathogen of Cheetahs and Other Big Cats

Dailidiene, Daiva, Dailide, Giedrius, Ogura, Keiji, Zhang, Maojun, Mukhopadhyay, Asish K., Eaton, Kathryn A., ...

Insights into bacterium-host interactions and genome evolution can emerge from comparisons among related species. Here we studied Helicobacter acinonychis (formerly H. acinonyx), a species closely...

Helicobacter pylori Induces IκB Kinase α Nuclear Translocation and Chemokine Production in Gastric Epithelial Cells

Hirata, Yoshihiro, Maeda, Shin, Ohmae, Tomoya, Shibata, Wataru, Yanai, Ayako, Ogura, Keiji, ...

NF-κB is an important transcriptional factor that is involved in multiple cellular responses, such as inflammation and antiapoptosis. IκB kinase α (IKKα) and IKKβ, which are critical regulators...

Quantitative Effect of luxS Gene Inactivation on the Fitness of Helicobacter pylori▿

Lee, Woo-Kon, Ogura, Keiji, Loh, John T., Cover, Timothy L., Berg, Douglas E.

Furanone metabolites called AI-2 (autoinducer 2), used by some bacterial species for signaling and cell density-regulated changes in gene expression, are made while regenerating S-adenosyl methionine...

Virulence Factors of Helicobacter pylori Responsible for Gastric Diseases in Mongolian Gerbil

Ogura, Keiji, Maeda, Shin, Nakao, Masafumi, Watanabe, Takeshi, Tada, Mayumi, Kyutoku, Toshimasa, ...

Helicobacter pylori infection induces various gastroduodenal diseases. We examined the role of two genes, vacA and cagE, in the gastric pathogenesis induced by H. pylori using a long-term (62 wk)...

Activation of IκB Kinase β and NF-κB Is Essential for Helicobacter pylori-Induced Chronic Gastritis in Mongolian Gerbils▿

Yanai, Ayako, Maeda, Shin, Shibata, Wataru, Hikiba, Yohko, Sakamoto, Kei, Nakagawa, Hayato, ...

The Mongolian gerbil model of Helicobacter pylori infection resembles human gastritis. In this study, we investigated the role of NF-κB activation in H. pylori-infected gerbils. Activated...

A case of rectal Dieulafoy’s ulcer and successful endoscopic band ligation

Yoshikumi, Yukako, Mashima, Hirosato, Suzuki, Junko, Yamaji, Yutaka, Okamoto, Makoto, Ogura, Keiji, ...

Dieulafoy’s ulcer is a rare cause of gastrointestinal bleeding. The lesion is usually located in the stomach, although it may occur anywhere in the gastrointestinal tract. A 44-year-old man was...