Complete blockage of the mevalonate pathway results in male gametophyte lethality (2009)
Suzuki, Masashi, Nakagawa, Shoko, Kamide, Yukiko, Kobayashi, Keiko, Ohyama, Kiyoshi, Hashinokuchi, Hiromi, ...
Plants have two isoprenoid biosynthetic pathways: the cytosolic mevalonate (MVA) pathway and the plastidic 2-C-methyl-D-erythritol 4-phosphate (MEP) pathway. Since the discovery of the MEP pathway,...
Layla Parker-Katiraee, Andrew R. Carson, Takahiro Yamada, Philippe Arnaud, Robert Feil, ...
Imprinted genes are expressed in a parent-of-origin manner and are located in clusters throughout the genome. Aberrations in the expression of imprinted genes on human Chromosome 7 have been...
Layla Parker-Katiraee, Andrew R Carson, Takahiro Yamada, Philippe Arnaud, Robert Feil, ...
Imprinted genes are expressed in a parent-of-origin manner and are located in clusters throughout the genome. Aberrations in the expression of imprinted genes on human chromosome 7 have been...
Kobayashi, Keiko, Suzuki, Masashi, Tang, Jianwei, Nagata, Noriko, Ohyama, Kiyoshi, Seki, Hikaru, ...
Higher plants have two metabolic pathways for isoprenoid biosynthesis: the cytosolic mevalonate (MVA) pathway and the plastidal non-mevalonate (MEP) pathway. Despite the compartmentalization of these...
Geib, Dona J., Millstein, Mark., Epuré, Serban., Wright, Richard., Rubin, Cynthia Beth., Koen, Viktor., ...
Leonardo - Volume 34, Number 5, October 2001
Yoshino-Yasuda, Izumi, Kobayashi, Keiko, Akiyama, Masashi, Itoh, Hirotaka, Tomomura, Akito, Saheki, Takeyori
As reported previously, caldecrin, a serum calcium-decreasing factor, from pancreas was found to be a serine protease, but the proteolytic activity was not necessary for its serum calcium decreasing...
Kawachi, Hiroyuki, Atomi, Haruyuki, Ueda, Mitsuyoshi, Hashimoto, Noriko, Kobayashi, Keiko, Yoshida, Tomoko, ...
In an n-alkane-assimilating yeast, Candida tropicalis, carnitine acetyltransferase (CAT; EC 2.3.1.7) was localized in both peroxisomes and mitochondria. Both CATs were encoded by one gene, CT-CAT,...
Purification and Characterization of Thrombopoietin (1995)
Kato, Takashi, Ogami, Kinya, Shimada, Yoshihiro, Iwamatsu, Akihiro, Sohma, Yoshiaki, Akahori, Hiromichi, ...
A thrombopoietic factor, termed thrombopoietin (TPO), was highly purified directly from the plasma of sublethally irradiated 1, 100 rats by measuring the production of megakaryo-cytes from a highly...
Amino Acid Sequence of Rat Argininosuccinate Lyase Deduced from cDNA (1988)
Amaya, Yoshihiro, Matsubasa, Tadashi, Takiguchi, Masaki, Kobayashi, Keiko, Saheki, Takeyori, Kawamoto, Susumu, ...
Argininosuccinate lyase [EC 4.3.2.1] is an enzyme of the urea cycle in the liver of ureotelic animals. The enzymes of the urea cycle, including argininosuccinate lyase, are regulated developmentally...
End Group Analysis of the Cytosolic and Mitochondrial Fumarases from Rat Liver (1983)
KOBAYASHI, Keiko, TUBOI, Syozo
Some molecular properties of the cytosolic and mitochondrial fumarases were compared. The carboxyl(C)-terminal amino acid of both the cytosolic and mitochondrial fumarases of rat liver cell was...
Studies on the Turnover Rates of Cytosolic and Mitochondrial Fumarases in Rat Liver (1982)
KOBAYASHI, Keiko, KAMIMURA, Tadashi, TUBOI, Syozo
The turnover rates of mitochondrial and cytosolic fumarase in the rat liver were determined by injecting L-[U-14C]leucine and following the decay of specific radioactivity incorporated into...
KOBAYASHI, Keiko, YAMANISHI, Tomoko, TUBOI, Syozo
Fumarases located in the cytosolic and mitochondrial fractions were separately purified and crystallized from rat liver. Polyacrylamide gel electrophoresis of these two crystallized fumarases in the...
KOBAYASHI, Keiko, KATUNUMA, Nobuhiko
The kinetic constants of a serine protease from the muscle layer of rat small intestine for three ester substrates were compared with those reported for bovine chymotrypsin A. The Km values for...
Selective Cleavage of Peptide Bonds by a Serine Protease from Rat Skeletal Muscle (1978)
KOBAYASHI, Keiko, SANADA, Yukihiro, KATUNUMA, Nobuhiko
The selective cleavage of peptide bonds by a serine protease from skeletal muscle (SK-protease) was examined using glucagon and neurotensin as substrates. Among the peptide bonds cleaved in these...
KATO, Kanefusa, HAMAGUCHI, Yoshitaka, OKAWA, Sachiyo, ISHIKAWA, Eiji, KOBAYASHI, Keiko, KATUNUMA, Nobuhiko
Rabbit antibody IgG was bound onto aminoalkylsilyl or plain glass rods by simple adsorption. For comparison, rabbit antibody IgG was also bound onto glutaraldehyde-activated aminoalkylsilyl glass...
KATO, Kanefusa, HAMAGUCHI, Yoshitaka, OKAWA, Sachiyo, ISHIKAWA, Eiji, KOBAYASHI, Keiko, KATUNUMA, Nobuhiko
A highly sensitive sandwich enzymoimmunoassay of macromolecular antigens using the Fab' of rabbit antibody coupled to -β-D-galactosidase together with rabbit antibody IgG loaded on silicone pieces...
KOBAYASHI, Keiko, KITO, Kiyoaki, KATUNUMA, Nobuhiko
The turnover rates of ornithine aminotransferase in the liver and kidney of control rats and those treated with estrogen were determined by injecting L-[14C]leucine (U) and following the decay of...
KOBAYASHI, Keiko, MORRIS, Harold P., KATUNUMA, Nobuhiko
The ornithine aminotransferase [EC 2.6.1.13] content of Morris hepatoma 44 is about 15 times higher than that in normal liver. The turnover rates of ornithine aminotransferase in hepatoma 44 and host...
HAMAGUCHI, Yoshitaka, KATO, Kanefusa, FUKUI, Hideo, SHIRAKAWA, Isao, ISHIKAWA, Eiji, KOBAYASHI, Keiko, ...
A macromolecular antigen, ornithine δ-aminotransferase [EC 2. 6.1.13] from rat liver (OAT) was assayed by the sandwich procedure using a rabbit (anti-OAT) Fab'-β-D-galactosidase complex and rabbit...
MATSUDA, Yoshiko, KURODA, Yasuhiro, KOBAYASHI, Keiko, KATUNUMA, Nobuhiko
The mechanisms regulating serine, glycine, and glutamine metabolism were compared in ureotelic animals and uricotelic animals. The activities of five enzymes (glutaminase [EC 3.5.1.2], glutamine...
Characterization of the Enzymatic Component of Clostridium perfringens Iota-Toxin
Nagahama, Masahiro, Sakaguchi, Yoshihiko, Kobayashi, Keiko, Ochi, Sadayuki, Sakurai, Jun
The iotaa component (ia) of Clostridium perfringens ADP ribosylates nonmuscle β/γ actin and skeletal muscle α-actin. Replacement of Arg-295 in ia with alanine led to a complete loss of...
Binding Component of Clostridium perfringens Iota-Toxin Induces Endocytosis in Vero Cells
Nagahama, Masahiro, Nagayasu, Koichi, Kobayashi, Keiko, Sakurai, Jun
Clostridium perfringens iota-toxin is a binary toxin consisting of two individual proteins, the binding component (Ib) and the enzyme component (Ia). Wild-type Ib bound to Vero cells at 4 and 37°C...
Nishioka, Michiho, Kohno, Takashi, Tani, Masachika, Yanaihara, Nozomu, Tomizawa, Yoshio, Otsuka, Ayaka, ...
Loss of heterozygosity on chromosome 22q has been detected in approximately 60% of advanced nonsmall cell lung carcinoma (NSCLC) as well as small cell lung carcinoma (SCLC), suggesting the presence...
Sinasac, David S., Moriyama, Mitsuaki, Jalil, M. Abdul, Begum, Laila, Li, Meng Xian, Iijima, Mikio, ...
Adult-onset type II citrullinemia (CTLN2) is an autosomal recessive disease caused by mutations in SLC25A13, the gene encoding the mitochondrial aspartate/glutamate carrier citrin. The absence of...
Binding and Internalization of Clostridium perfringens Iota-Toxin in Lipid Rafts
Nagahama, Masahiro, Yamaguchi, Akiwo, Hagiyama, Tohko, Ohkubo, Noriko, Kobayashi, Keiko, Sakurai, Jun
Clostridium perfringens iota-toxin is a binary toxin composed of an enzymatic component (Ia) and a binding component (Ib). The oligomer of Ib formed in membranes induces endocytosis. We examined the...
Characterization of the Enzymatic Component of Clostridium perfringens Iota-Toxin
Nagahama, Masahiro, Sakaguchi, Yoshihiko, Kobayashi, Keiko, Ochi, Sadayuki, Sakurai, Jun
The iotaa component (ia) of Clostridium perfringens ADP ribosylates nonmuscle β/γ actin and skeletal muscle α-actin. Replacement of Arg-295 in ia with alanine led to a complete loss of...
Binding Component of Clostridium perfringens Iota-Toxin Induces Endocytosis in Vero Cells
Nagahama, Masahiro, Nagayasu, Koichi, Kobayashi, Keiko, Sakurai, Jun
Clostridium perfringens iota-toxin is a binary toxin consisting of two individual proteins, the binding component (Ib) and the enzyme component (Ia). Wild-type Ib bound to Vero cells at 4 and 37°C...
Nishioka, Michiho, Kohno, Takashi, Tani, Masachika, Yanaihara, Nozomu, Tomizawa, Yoshio, Otsuka, Ayaka, ...
Loss of heterozygosity on chromosome 22q has been detected in approximately 60% of advanced nonsmall cell lung carcinoma (NSCLC) as well as small cell lung carcinoma (SCLC), suggesting the presence...
Sinasac, David S., Moriyama, Mitsuaki, Jalil, M. Abdul, Begum, Laila, Li, Meng Xian, Iijima, Mikio, ...
Adult-onset type II citrullinemia (CTLN2) is an autosomal recessive disease caused by mutations in SLC25A13, the gene encoding the mitochondrial aspartate/glutamate carrier citrin. The absence of...
Binding and Internalization of Clostridium perfringens Iota-Toxin in Lipid Rafts
Nagahama, Masahiro, Yamaguchi, Akiwo, Hagiyama, Tohko, Ohkubo, Noriko, Kobayashi, Keiko, Sakurai, Jun
Clostridium perfringens iota-toxin is a binary toxin composed of an enzymatic component (Ia) and a binding component (Ib). The oligomer of Ib formed in membranes induces endocytosis. We examined the...
Parker-Katiraee, Layla, Carson, Andrew R, Yamada, Takahiro, Arnaud, Philippe, Feil, Robert, Abu-Amero, Sayeda N, ...
Imprinted genes are expressed in a parent-of-origin manner and are located in clusters throughout the genome. Aberrations in the expression of imprinted genes on human Chromosome 7 have been...
An Alternative Approach to the Monitoring of Respiration by Dynamic Air-Pressure Sensor
Takarada, Tohru, Kawahara, Michio, Irifune, Masahiro, Endo, Chie, Shimizu, Yoshitaka, Kobayashi, Keiko, ...
Monitoring and assessing of patient respiratory function during conscious sedation are important because many drugs used for conscious sedation produce respiratory depression and subsequent...
Complete blockage of the mevalonate pathway results in male gametophyte lethality
Suzuki, Masashi, Nakagawa, Shoko, Kamide, Yukiko, Kobayashi, Keiko, Ohyama, Kiyoshi, Hashinokuchi, Hiromi, ...
Plants have two isoprenoid biosynthetic pathways: the cytosolic mevalonate (MVA) pathway and the plastidic 2-C-methyl-D-erythritol 4-phosphate (MEP) pathway. Since the discovery of the MEP pathway,...